Table 1.

Training data and metabolic measurements

All SubjectsHigh-Intensity GroupModerate-Intensity GroupLow-Intensity Group
T1 T2 T3 T1T2 T3 T1 T2 T3 T1 T2 T3
n 21 21 21 9 9 9 10 10 10 2 22
Age, yr 50.5 ± 8.5 60.2* ± 8.8 70.4 ± 8.8 51.2 ± 7.6 60.4* ± 8.5 70.4 ± 8.5 49.5 ± 10.3 59.5* ± 10.3 69.8 ± 10.2 52.5 ± 2.1 62.5* ± 2.1 73.5 ± 2.1
Follow-up, yr 9.8 ± 1.4 20.0 ± 1.3 9.2 ± 1.9 19.3 ± 1.7 10.1 ± 0.7 20.4 ± 0.7 10.6 ± 0.1 20.9 ± 0
Mileage, miles/wk 32.8 ± 23.8 27.1 ± 15.2 18.2* ± 11.7 38.3 ± 24.3 34.4 ± 18.9 21.9 ± 15.2 30.6 ± 25.5 23.5 ± 8.5 17.0* ± 7.6 18.8 ± 5.3 12.0 ± 4.2 7.5 ± 0.7
Pace, min/miles 7.9 ± 1.3 8.6 ± 1.6 10.41-153 ± 3.2 7.9 ± 1.4 8.3 ± 1.5 9.5 ± 1.3 7.9 ± 1.4 8.7 ± 1.8 10.0 ± 3.4 7.4 ± 0.1 8.8 ± 0.4 16.3 ± 1.8
HRrest, beats/min 49 ± 8 48 ± 8 52 ± 8 46 ± 7 47 ± 9 50 ± 10 52 ± 8 49 ± 7 54 ± 5 50 ± 3 48 ± 11 56 ± 8
HRmax, beats/min 174 ± 10 167* ± 10 161* ± 9 173 ± 13 165* ± 10 160 ± 9 177 ± 8 171* ± 9 162 ± 9 166 ± 6 159 ± 8 163 ± 3
o 2 max
 l/min 3.792 ± 0.615 3.465 ± 0.545 2.8631-153 ± 0.715 3.643 ± 0.470 3.390* ± 0.440 2.849 ± 0.526 3.930 ± 0.750 3.593* ± 0.663 3.009 ± 0.875 3.770 ± 0.580 3.165* ± 0.199 2.197 ± 0.008
 ml ⋅ kg−1 ⋅ min−1 54.3 ± 8.0 50.1* ± 7.0 40.5 ± 8.9 55.4 ± 8.7 52.1* ± 6.8 43.2 ± 6.3 54.2 ± 7.7 50.0* ± 6.9 40.8 ± 9.5 50.0 ± 8.7 42.3* ± 1.3 27.0 ± 0.1
 ml ⋅ kg FFW−1 ⋅ min−1 61.7 ± 7.5 58.7 ± 6.8 48.71-153 ± 9.8 61.6 ± 9.0 59.7 ± 7.3 51.1 ± 8.5 62.3 ± 6.4 59.2* ± 6.4 49.3 ± 10.0 59.0 ± 9.6 51.4* ± 1.7 34.5 ± 0.2
O2 pulse, ml/beat 21.9 ± 3.7 20.8 ± 3.3 17.81-153 ± 4.7 21.2 ± 3.0 20.5 ± 2.3 17.8 ± 3.2 22.3 ± 4.6 21.1 ± 4.4 18.6 ± 5.9 22.7 ± 2.7 20.0 ± 0.3 13.5 ± 0.3
e max, l/minbtps 144.0 ± 23.4 151.4 ± 20.0 117.4 ± 24.7 143.0 ± 19.4 148.6 ± 18.3 117.5 ± 14.7 145.5 ± 29.8 154.6 ± 23.9 122.3 ± 31.1 142.0 ± 15.6 147.9 ± 2.7 92.2 ± 14.4
RER 1.11 ± 0.07 1.11 ± 0.05 1.13 ± 0.07 1.10 ± 0.08 1.11 ± 0.06 1.12 ± 0.05 1.11 ± 0.07 1.09 ± 0.05 1.14 ± 0.08 1.14 ± 0.01 1.14 ± 0.02 1.15 ± 0.06
Perceived exertion 19.1 ± 0.8 19.2 ± 0.8 19.3 ± 0.7 19.1 ± 0.3 19.0 ± 0.9 19.2 ± 1.0 18.5 ± 0.7 19.5 ± 0.7
  • Values are means ± SD; n, no. of subjects exceptn = 20 for all subjects and 8 for high-intensity group initial evaluation (T1) respiratory exchange ratio (RER) and n = 20 for all subjects and 9 for moderate-intensity group T1 resting heart rate (HRrest) and maximal ventilation (V˙e max). T2, 10-yr follow-up; T3, 20-yr follow-up; HRmax, maximal HR;V˙o 2 max, maximal O2 uptake; FFW, fat-free weight. Significant difference (P ≤ 0.05):

  • * from T1;

  • T2 vs. T3;

  • T1 vs. T3 and T2 vs. T3.

  • F1-153 Group by time interaction.