Table 1.
Normoxia (21%)Hypoxia (12.5%)
VO2, ml/min, STPD3,685 (728)2,893 (630)
Cardiac output, l/min24.9 (5.1)24.6 (5.4)
Intrapulmonary shunt, %0.2 (0.7)0.1 (0.3)
AaDO2, Torr19 (10)21 (7)
AaDO2 from Shunt, Torr1.40.1
% of AaDO2 from shunt7.40.005
  • Values in parentheses are SD. Metabolic and gas exchange data during very heavy exercise in normoxia (n = 64) and hypoxia (n = 57) from previously published studies (5, 6, 11–13). In all cases the measured intrapulmonary shunt measured by the multiple inert gas technique was less than 1% of cardiac output and had a minimal effect on pulmonary gas exchange.