Table 1.

Body composition, aerobic fitness, leptinemia, and insulin sensitivity

VariableEucaloric GroupHypocaloric Group
Age, yr66±167±1
Weight, kg96.2±5.492.9±5.195.3±4.787.4±4.2
BMI, kg/m234.7±1.633.5±1.533.6±1.330.8±1.2
FM, kg42.3±2.440.1±2.6*37.6±2.831.6±2.6
FFM, kg54.4±3.553.0±3.057.7±3.455.8±3.3
WC, cm117±4113±3*113±3107±3
o2 max, ml·kg FFM−1·min−134.6±1.038.3±1.436.3±1.240.1±1.2*
Leptin, ng/ml25.8±3.922.4±3.5*20.4±4.512.6±2.7
Adiponectin, μg/ml7.66±1.166.85±1.657.60±0.926.57±0.93
Clamp M, mg·kg FFM−1·min−12.97±0.434.21±0.66*2.92±0.344.68±0.56
  • Values are means ± SE. Volunteers underwent a 12-wk aerobic exercise training intervention with either a eucaloric (∼1,900 kcal/day) or a hypocaloric (∼1,300 kcal/day) diet. BMI, body mass index; FM, fat mass; FFM, fat-free mass; WC, waist circumference; V̇o2 max, maximal oxygen uptake during exhaustive exercise; Clamp M, mean glucose disposal rate during the last 30 min of a hyperinsulinemic euglycemic clamp.

  • * Significant differences from baseline: P < 0.05,

  • Significant differences from baseline: P < 0.01,

  • Significant differences from baseline: P < 0.001.

  • Group × time interactions were found with weight, BMI, FM, and leptin (all P < 0.05).