Journal of Applied Physiology -- Table of Contents (May 2008, 104, (5))

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INVITED EDITORIAL

William G. Schrage: Not a search in vein: novel stimulus for vascular dysfunction after simulated microgravity
J Appl Physiol 104: 1257-1258, 2008. First published February 14, 2008; doi:10.1152/japplphysiol.00174.2008 [Full Text] [PDF]

William P. Santamore and Alfred A. Bove: Why are arteries the size they are?
J Appl Physiol 104: 1259-1259, 2008. First published March 20, 2008; doi:10.1152/japplphysiol.90391.2008 [Full Text] [PDF]

David F. Donnelly: Assisting Mother Nature in postnatal chemoreceptor maturation
J Appl Physiol 104: 1260-1261, 2008; doi:10.1152/japplphysiol.90312.2008 [Full Text] [PDF]

Michael D. Delp: Unraveling the complex web of impaired wound healing with mechanical unloading and physical deconditioning
J Appl Physiol 104: 1262-1263, 2008. First published March 20, 2008; doi:10.1152/japplphysiol.90393.2008 [Full Text] [PDF]

Henriette Pilegaard and Erik A. Richter: PGC-1 ${alpha}$ : important for exercise performance?
J Appl Physiol 104: 1264-1265, 2008; doi:10.1152/japplphysiol.90346.2008 [Full Text] [PDF]

INVITED REVIEWS

Ghassan S. Kassab, Jose A. Navia, Keith March, and Jenny Susana Choy: Coronary venous retroperfusion: an old concept, a new approach
J Appl Physiol 104: 1266-1272, 2008. First published February 21, 2008; doi:10.1152/japplphysiol.00063.2008 [Abstract] [Full Text] [PDF]

ARTICLES

Bradley J. Behnke, David C. Zawieja, Anatoliy A. Gashev, Chester A. Ray, and Michael D. Delp: Diminished mesenteric vaso- and venoconstriction and elevated plasma ANP and BNP with simulated microgravity
J Appl Physiol 104: 1273-1280, 2008. First published January 24, 2008; doi:10.1152/japplphysiol.00954.2006 [Abstract] [Full Text] [PDF]

Jenny Susana Choy and Ghassan S. Kassab: Scaling of myocardial mass to flow and morphometry of coronary arteries
J Appl Physiol 104: 1281-1286, 2008. First published March 6, 2008; doi:10.1152/japplphysiol.01261.2007 [Abstract] [Full Text] [PDF]

Anita Pawar, Ying-Jie Peng, Frank J. Jacono, and Nanduri R. Prabhakar: Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia
J Appl Physiol 104: 1287-1294, 2008. First published January 10, 2008; doi:10.1152/japplphysiol.00644.2007 [Abstract] [Full Text] [PDF]

Katherine A. Radek, Lisa A. Baer, Jennifer Eckhardt, Luisa A. DiPietro, and Charles E. Wade: Mechanical unloading impairs keratinocyte migration and angiogenesis during cutaneous wound healing
J Appl Physiol 104: 1295-1303, 2008. First published February 21, 2008; doi:10.1152/japplphysiol.00977.2007 [Abstract] [Full Text] [PDF]

Jennifer A. Calvo, Thomas G. Daniels, Xiaomei Wang, Angelika Paul, Jiandie Lin, Bruce M. Spiegelman, Susan C. Stevenson, and Shamina M. Rangwala: Muscle-specific expression of PPAR ${gamma}$ coactivator-1 ${alpha}$ improves exercise performance and increases peak oxygen uptake
J Appl Physiol 104: 1304-1312, 2008. First published January 31, 2008; doi:10.1152/japplphysiol.01231.2007 [Abstract] [Full Text] [PDF]

Thomas P. J. Solomon, Sakita N. Sistrun, Raj K. Krishnan, Luis F. Del Aguila, Christine M. Marchetti, Susan M. O'Carroll, Valerie B. O'Leary, and John P. Kirwan: Exercise and diet enhance fat oxidation and reduce insulin resistance in older obese adults
J Appl Physiol 104: 1313-1319, 2008. First published March 6, 2008; doi:10.1152/japplphysiol.00890.2007 [Abstract] [Full Text] [PDF]

Taija Finni, Marko Havu, Shantanu Sinha, Jussi-Pekka Usenius, and Sulin Cheng: Mechanical behavior of the quadriceps femoris muscle tendon unit during low-load contractions
J Appl Physiol 104: 1320-1328, 2008. First published March 13, 2008; doi:10.1152/japplphysiol.01069.2007 [Abstract] [Full Text] [PDF] [Supplemental Video]

Apiradee Thammanomai, Lauren E. Hueser, Arnab Majumdar, Erzsébet Bartolák-Suki, and Béla Suki: Design of a new variable-ventilation method optimized for lung recruitment in mice
J Appl Physiol 104: 1329-1340, 2008. First published March 13, 2008; doi:10.1152/japplphysiol.01002.2007 [Abstract] [Full Text] [PDF]

Gaspar R. Chiappa, Audrey Borghi-Silva, Leonardo F. Ferreira, Claúdia Carrascosa, Cristino Carneiro Oliveira, Joyce Maia, Ana Cristina Gimenes, Fernando Queiroga, Jr, Danilo Berton, Eloara M. V. Ferreira, Luis Eduardo Nery, and J. Alberto Neder: Kinetics of muscle deoxygenation are accelerated at the onset of heavy-intensity exercise in patients with COPD: relationship to central cardiovascular dynamics
J Appl Physiol 104: 1341-1350, 2008. First published March 20, 2008; doi:10.1152/japplphysiol.01364.2007 [Abstract] [Full Text] [PDF]

Jianguo Zhuang, Fadi Xu, and Donald T. Frazier: Hyperventilation evoked by activation of the vicinity of the caudal inferior olivary nucleus depends on the fastigial nucleus in anesthetized rats
J Appl Physiol 104: 1351-1358, 2008. First published March 20, 2008; doi:10.1152/japplphysiol.00824.2007 [Abstract] [Full Text] [PDF]

Craig D. Tokuno, S. Jayne Garland, Mark G. Carpenter, Alf Thorstensson, and Andrew G. Cresswell: Sway-dependent modulation of the triceps surae H-reflex during standing
J Appl Physiol 104: 1359-1365, 2008. First published March 27, 2008; doi:10.1152/japplphysiol.00857.2007 [Abstract] [Full Text] [PDF]

Marcella A. Raney and Lorraine P. Turcotte: Evidence for the involvement of CaMKII and AMPK in Ca²⁺-dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle
J Appl Physiol 104: 1366-1373, 2008. First published February 28, 2008; doi:10.1152/japplphysiol.01282.2007 [Abstract] [Full Text] [PDF]

Colin N. Young, Raju Y. Prasad, Adam M. Fullenkamp, Michael E. Stillbower, William B. Farquhar, and David G. Edwards: Ultrasound assessment of popliteal vein compliance during a short deflation protocol
J Appl Physiol 104: 1374-1380, 2008. First published February 28, 2008; doi:10.1152/japplphysiol.00825.2007 [Abstract] [Full Text] [PDF]

Robert H. Brown, David W. Kaczka, Katherine Fallano, Sining Chen, and Wayne Mitzner: Temporal variability in the responses of individual canine airways to methacholine
J Appl Physiol 104: 1381-1386, 2008. First published February 28, 2008; doi:10.1152/japplphysiol.01348.2007 [Abstract] [Full Text] [PDF]

D. H. J. Thijssen, M. Kooijman, P. C. E. de Groot, M. W. P. Bleeker, P. Smits, D. J. Green, and M. T. E. Hopman: Endothelium-dependent and -independent vasodilation of the superficial femoral artery in spinal cord-injured subjects
J Appl Physiol 104: 1387-1393, 2008. First published February 28, 2008; doi:10.1152/japplphysiol.01039.2007 [Abstract] [Full Text] [PDF]

David F. Donnelly: Spontaneous action potential generation due to persistent sodium channel currents in simulated carotid body afferent fibers
J Appl Physiol 104: 1394-1401, 2008. First published February 28, 2008; doi:10.1152/japplphysiol.01169.2007 [Abstract] [Full Text] [PDF]

Kathy L. Ryan, William H. Cooke, Caroline A. Rickards, Keith G. Lurie, and Victor A. Convertino: Breathing through an inspiratory threshold device improves stroke volume during central hypovolemia in humans
J Appl Physiol 104: 1402-1409, 2008. First published February 28, 2008; doi:10.1152/japplphysiol.00439.2007 [Abstract] [Full Text] [PDF]

Eloi F. Rosa, Edna Freymüller, Silvia S. M. Ihara, Jeannine Aboulafia, and Viviane L. A. Nouailhetas: Damaging effects of intense repetitive treadmill running on murine intestinal musculature
J Appl Physiol 104: 1410-1417, 2008. First published February 28, 2008; doi:10.1152/japplphysiol.00377.2007 [Abstract] [Full Text] [PDF]

Andrew T. Lovering, Lee M. Romer, Hans C. Haverkamp, David F. Pegelow, John S. Hokanson, and Marlowe W. Eldridge: Intrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humans
J Appl Physiol 104: 1418-1425, 2008. First published February 21, 2008; doi:10.1152/japplphysiol.00208.2007 [Abstract] [Full Text] [PDF]

Danny J. Eckert, R. Doug McEvoy, Kate E. George, Kieron J. Thomson, and Peter G. Catcheside: Effects of hypoxia on genioglossus and scalene reflex responses to brief pulses of negative upper-airway pressure during wakefulness and sleep in healthy men
J Appl Physiol 104: 1426-1435, 2008. First published February 21, 2008; doi:10.1152/japplphysiol.01056.2007 [Abstract] [Full Text] [PDF]

Frédéric N. Daussin, Joffrey Zoll, Elodie Ponsot, Stéphane P. Dufour, Stéphane Doutreleau, Evelyne Lonsdorfer, Renée Ventura-Clapier, Bertrand Mettauer, François Piquard, Bernard Geny, and Ruddy Richard: Training at high exercise intensity promotes qualitative adaptations of mitochondrial function in human skeletal muscle
J Appl Physiol 104: 1436-1441, 2008. First published February 21, 2008; doi:10.1152/japplphysiol.01135.2007 [Abstract] [Full Text] [PDF]

Bryan J. Taylor and Lee M. Romer: Effect of expiratory muscle fatigue on exercise tolerance and locomotor muscle fatigue in healthy humans
J Appl Physiol 104: 1442-1451, 2008. First published March 6, 2008; doi:10.1152/japplphysiol.00428.2007 [Abstract] [Full Text] [PDF]

Micah J. Drummond, Hans C. Dreyer, Bart Pennings, Christopher S. Fry, Shaheen Dhanani, Edgar L. Dillon, Melinda Sheffield-Moore, Elena Volpi, and Blake B. Rasmussen: Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging
J Appl Physiol 104: 1452-1461, 2008. First published March 6, 2008; doi:10.1152/japplphysiol.00021.2008 [Abstract] [Full Text] [PDF]

J. L. Wright and A. Churg: Short-term exposure to cigarette smoke induces endothelial dysfunction in small intrapulmonary arteries: analysis using guinea pig precision cut lung slices
J Appl Physiol 104: 1462-1469, 2008. First published March 20, 2008; doi:10.1152/japplphysiol.00520.2007 [Abstract] [Full Text] [PDF]

Adlah Sukkar, John Jenkins, Jesús Sánchez, and Elizabeth M. Wagner: Inhibition of CXCR₂ attenuates bronchial angiogenesis in the ischemic rat lung
J Appl Physiol 104: 1470-1475, 2008. First published March 6, 2008; doi:10.1152/japplphysiol.00974.2007 [Abstract] [Full Text] [PDF]

David J. Kosek and Marcas M. Bamman: Modulation of the dystrophin-associated protein complex in response to resistance training in young and older men
J Appl Physiol 104: 1476-1484, 2008. First published March 20, 2008; doi:10.1152/japplphysiol.00708.2007 [Abstract] [Full Text] [PDF]

Cynthia M. Otto, Klaus Markstaller, Osamu Kajikawa, Jens Karmrodt, Rebecca S. Syring, Birgit Pfeiffer, Virginia P. Good, Charles W. Frevert, and James E. Baumgardner: Spatial and temporal heterogeneity of ventilator-associated lung injury after surfactant depletion
J Appl Physiol 104: 1485-1494, 2008. First published March 6, 2008; doi:10.1152/japplphysiol.01089.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]

Seth-Emil T. Bartel, Susan E. Haywood, Jason C. Woods, Yulin V. Chang, Christopher Menard, Dmitriy A. Yablonskiy, David S. Gierada, and Mark S. Conradi: Role of collateral paths in long-range diffusion in lungs
J Appl Physiol 104: 1495-1503, 2008. First published February 21, 2008; doi:10.1152/japplphysiol.01005.2007 [Abstract] [Full Text] [PDF]

INNOVATIVE METHODOLOGY

Leszek Kalinowski, Lawrence W. Dobrucki, David F. Meoli, Donald P. Dione, Mehran M. Sadeghi, Joseph A. Madri, and Albert J. Sinusas: Targeted imaging of hypoxia-induced integrin activation in myocardium early after infarction
J Appl Physiol 104: 1504-1512, 2008. First published March 20, 2008; doi:10.1152/japplphysiol.00861.2007 [Abstract] [Full Text] [PDF]

HIGHLIGHTED TOPICS

Paul A. Gray: Transcription factors and the genetic organization of brain stem respiratory neurons
J Appl Physiol 104: 1513-1521, 2008. First published January 24, 2008; doi:10.1152/japplphysiol.01383.2007 [Abstract] [Full Text] [PDF]

C. Gaultier and J Gallego: Neural control of breathing: insights from genetic mouse models
J Appl Physiol 104: 1522-1530, 2008. First published January 24, 2008; doi:10.1152/japplphysiol.01266.2007 [Abstract] [Full Text] [PDF]

POINT-COUNTERPOINT

Michael Hughes and John B. West: Point:Counterpoint: Gravity is/is not the major factor determining the distribution of blood flow in the human lung
J Appl Physiol 104: 1531-1533, 2008. First published November 15, 2007; doi:10.1152/japplphysiol.01092.2007 [Full Text] [PDF] [Correction]

Robb Glenny: Counterpoint: Gravity is not the major factor determining the distribution of blood flow in the healthy human lung
J Appl Physiol 104: 1533-1535, 2008; doi:10.1152/japplphysiol.01092.2007a [Full Text] [PDF]

: Rebuttal from Drs. Hughes and West
J Appl Physiol 104: 1535-1535, 2008; doi:10.1152/japplphysiol.01092.2007b [Full Text] [PDF]

: Rebuttal from Dr. Glenny
J Appl Physiol 104: 1535-1536, 2008; doi:10.1152/japplphysiol.01092.2007c [Full Text] [PDF]

Michael Hughes and John B. West: Last Word on Point:Counterpoint: Gravity is/is not the major factor determining the distribution of blood flow in the human lung
J Appl Physiol 104: 1539-1539, 2008; doi:10.1152/japplphysiol.90374.2008 [Full Text] [PDF]

Robb Glenny: Last Word on Point:Counterpoint: Gravity is/is not the major factor determining the distribution of blood flow in the human lung
J Appl Physiol 104: 1540-1540, 2008. First published March 27, 2008; doi:10.1152/japplphysiol.90403.2008 [Full Text] [PDF]

POINT-COUNTERPOINT COMMENTS

Peter D. Wagner, Wiltz W. Wagner, Jr., Susan R. Hopkins, G. Kim Prisk, Kelly S. Burrowes, and Merryn H. Tawhai: Gravity is/is not the major factor determining the distribution of blood flow in the human lung
J Appl Physiol 104: 1537-1538, 2008; doi:10.1152/japplphysiol.90402.2008 [Full Text] [PDF]

LETTERS TO THE EDITOR

Claudio Marabotti, Remo Bedini, and Antonio L'Abbate: Right ventricular volume determination: not a matter for echocardiography
J Appl Physiol 104: 1547-1547, 2008; doi:10.1152/japplphysiol.00065.2008 [Full Text] [PDF]

Ralph Potkin, Robert Siegel, and Victor Cheng: Reply from Potkin, Siegel, and Chen
J Appl Physiol 104: 1548-1548, 2008; doi:10.1152/japplphysiol.00101.2008 [Full Text] [PDF]

VIEWPOINT

Mark Hargreaves: Fatigue mechanisms determining exercise performance: integrative physiology is systems biology
J Appl Physiol 104: 1541-1542, 2008. First published January 31, 2008; doi:10.1152/japplphysiol.00088.2008 [Full Text] [PDF]

Markus Amann, Samuele M. Marcora, Lars Nybo, Todd A. Duhamel, Timothy David Noakes, Vincent Jaquinandi, Jean Louis Saumet, Pierre Abraham, Bill T. Ameredes, Mark Burnley, Andrew M. Jones, Simon C. Gandevia, Jane E. Butler, and Janet L. Taylor: Commentaries on Viewpoint: Fatigue mechanisms determining exercise performance: Integrative physiology is systems physiology
J Appl Physiol 104: 1543-1546, 2008; doi:10.1152/japplphysiol.90427.2008 [Full Text] [PDF]

Cover

Cover: The April through June 2008 Highlighted Topics series examines the Neural Control of Perinatal Respiration in a series of review articles written by a panel of international experts. This series was conceived and edited by Guest Editor Dr. John Greer and Coordinating Associate Editor Dr. Ralph Fregosi. We acknowledge Steve Graepel, illustrator of the cover design. This illustration is copyrighted by Steve Graepel and reproduced with permission.