ESSAYS ON APS CLASSIC PAPERS

K. M. Baldwin

Editorial Focus  Comments on Classical Papers
J Appl Physiol 99: 1241-1242, 2005; doi:10.1152/classicessays.00036.2005 [Abstract] [Full Text] [PDF]  

EDITORIAL

Susan Redline and Judith Neubauer

Beyond the Fat Boy: the intertwining pathophysiologies of sleep apnea
J Appl Physiol 99: 1243-1244, 2005; doi:10.1152/japplphysiol.00840.2005 [Full Text] [PDF]  

INVITED EDITORIAL

Thomas Clanton

Yet another oxygen paradox
J Appl Physiol 99: 1245-1246, 2005; doi:10.1152/japplphysiol.00609.2005 [Full Text] [PDF]  

José Magalhães, António Ascensão, José M. C. Soares, Rita Ferreira, Maria J. Neuparth, Franklim Marques, and José A. Duarte

Acute and severe hypobaric hypoxia increases oxidative stress and impairs mitochondrial function in mouse skeletal muscle
J Appl Physiol 99: 1247-1253, 2005. First published May 19, 2005; doi:10.1152/japplphysiol.01324.2004 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY

Eloi F. Rosa, Antonio C. Silva, Silvia S. M. Ihara, Oswaldo A. Mora, Jeannine Aboulafia, and Viviane L. A. Nouailhetas

Habitual exercise program protects murine intestinal, skeletal, and cardiac muscles against aging
J Appl Physiol 99: 1569-1575, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.00417.2005 [Abstract] [Full Text] [PDF]  

Carlos L. del Rio, Patrick I. McConnell, Bradley D. Clymer, Roger Dzwonczyk, Robert E. Michler, George E. Billman, and Michael B. Howie

Early time course of myocardial electrical impedance during acute coronary artery occlusion in pigs, dogs, and humans
J Appl Physiol 99: 1576-1581, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.00830.2004 [Abstract] [Full Text] [PDF]  

Donna R. Hill, Marianne E. Brunner, Deborah C. Schmitz, Catherine C. Davis, Janine A. Flood, Patrick M. Schlievert, Sherry Z. Wang-Weigand, and Thomas W. Osborn

In vivo assessment of human vaginal oxygen and carbon dioxide levels during and post menses
J Appl Physiol 99: 1582-1591, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.01422.2004 [Abstract] [Full Text] [PDF]  

ARTICLES

Keith Stokes, Mary Nevill, Jan Frystyk, Henryk Lakomy, and George Hall

Human growth hormone responses to repeated bouts of sprint exercise with different recovery periods between bouts
J Appl Physiol 99: 1254-1261, 2005. First published May 26, 2005; doi:10.1152/japplphysiol.00839.2004 [Abstract] [Full Text] [PDF]  

Fabrizio Racca, Lorenzo Appendini, Cesare Gregoretti, Elisa Stra, Antonio Patessio, Claudio F. Donner, and V. Marco Ranieri

Effectiveness of mask and helmet interfaces to deliver noninvasive ventilation in a human model of resistive breathing
J Appl Physiol 99: 1262-1271, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.01363.2004 [Abstract] [Full Text] [PDF]  

Jennifer Rogers and Don D. Sheriff

Is there a threshold duration of vascular occlusion for hindlimb reactive hyperemia?
J Appl Physiol 99: 1272-1277, 2005; doi:10.1152/japplphysiol.00428.2005 [Abstract] [Full Text] [PDF]  

L. E. Young, K. Rogers, and J. L. N. Wood

Left ventricular size and systolic function in Thoroughbred racehorses and their relationships to race performance
J Appl Physiol 99: 1278-1285, 2005. First published May 26, 2005; doi:10.1152/japplphysiol.01319.2004 [Abstract] [Full Text] [PDF]  

Richard M. Effros, Barry Peterson, Richard Casaburi, Jennifer Su, Marshall Dunning, John Torday, Julie Biller, and Reza Shaker

Epithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects
J Appl Physiol 99: 1286-1292, 2005. First published May 26, 2005; doi:10.1152/japplphysiol.00362.2005 [Abstract] [Full Text] [PDF]  

Michiel W. P. Bleeker, Patricia C. E. De Groot, Gerard A. Rongen, Jörn Rittweger, Dieter Felsenberg, Paul Smits, and Maria T. E. Hopman

Vascular adaptation to deconditioning and the effect of an exercise countermeasure: results of the Berlin Bed Rest study
J Appl Physiol 99: 1293-1300, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.00118.2005 [Abstract] [Full Text] [PDF]  

André De Troyer, Matteo Cappello, and Pierre Scillia

Effect of inflation on the interaction between the left and right hemidiaphragms
J Appl Physiol 99: 1301-1307, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.00192.2005 [Abstract] [Full Text] [PDF]  

Douglas A. Syme, Kristin Evashuk, Benjamin Grintuch, Enrico L. Rezende, and Theodore Garland, Jr.

Contractile abilities of normal and "mini" triceps surae muscles from mice (Mus domesticus) selectively bred for high voluntary wheel running
J Appl Physiol 99: 1308-1316, 2005. First published June 9, 2005; doi:10.1152/japplphysiol.00369.2005 [Abstract] [Full Text] [PDF]  

Maarten W. Peeters, Martine A. Thomis, Hermine H. M. Maes, Gaston P. Beunen, Ruth J. F. Loos, Albrecht L. Claessens, and Robert Vlietinck

Genetic and environmental determination of tracking in static strength during adolescence
J Appl Physiol 99: 1317-1326, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.00021.2005 [Abstract] [Full Text] [PDF]  

Nicolette C. Bishop, Gary J. Walker, Lee A. Bowley, Kate F. Evans, Karen Molyneux, Fiona A. Wallace, and Alice C. Smith

Lymphocyte responses to influenza and tetanus toxoid in vitro following intensive exercise and carbohydrate ingestion on consecutive days
J Appl Physiol 99: 1327-1335, 2005. First published May 26, 2005; doi:10.1152/japplphysiol.00038.2005 [Abstract] [Full Text] [PDF]  

S. A. Evans, A. D. Parsons, and J. M. Overton

Homeostatic responses to caloric restriction: influence of background metabolic rate
J Appl Physiol 99: 1336-1342, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.01380.2004 [Abstract] [Full Text] [PDF]  

David Ricart-Jané, Pilar Cejudo-Martín, Julia Peinado-Onsurbe, M. Dolores López-Tejero, and Miquel Llobera

Changes in lipoprotein lipase modulate tissue energy supply during stress
J Appl Physiol 99: 1343-1351, 2005. First published June 9, 2005; doi:10.1152/japplphysiol.00971.2004 [Abstract] [Full Text] [PDF]  

Timothy A. Butterfield, Timothy R. Leonard, and Walter Herzog

Differential serial sarcomere number adaptations in knee extensor muscles of rats is contraction type dependent
J Appl Physiol 99: 1352-1358, 2005. First published June 9, 2005; doi:10.1152/japplphysiol.00481.2005 [Abstract] [Full Text] [PDF]  

Laura J. Cluberton, Sean L. McGee, Robyn M. Murphy, and Mark Hargreaves

Effect of carbohydrate ingestion on exercise-induced alterations in metabolic gene expression
J Appl Physiol 99: 1359-1363, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.00197.2005 [Abstract] [Full Text] [PDF]  

Cindy Thamrin, Peter D. Sly, and Zoltán Hantos

Broadband frequency dependence of respiratory impedance in rats
J Appl Physiol 99: 1364-1371, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.00383.2005 [Abstract] [Full Text] [PDF]  

A. Marcuello, J. González-Alonso, J. A. L. Calbet, R. Damsgaard, M. J. López-Pérez, and C. Díez-Sánchez

Skeletal muscle mitochondrial DNA content in exercising humans
J Appl Physiol 99: 1372-1377, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.00289.2005 [Abstract] [Full Text] [PDF]  

Jason D. Gardner, Gregory L. Brower, and Joseph S. Janicki

Effects of dietary phytoestrogens on cardiac remodeling secondary to chronic volume overload in female rats
J Appl Physiol 99: 1378-1383, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.01141.2004 [Abstract] [Full Text] [PDF]  

Motohiko Miyachi, Hirofumi Tanaka, Hiroshi Kawano, Mayumi Okajima, and Izumi Tabata

Lack of age-related decreases in basal whole leg blood flow in resistance-trained men
J Appl Physiol 99: 1384-1390, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.00061.2005 [Abstract] [Full Text] [PDF]  

Jennifer L. Losapio, Randy S. Sprague, Andrew J. Lonigro, and Alan H. Stephenson

5,6-EET-induced contraction of intralobar pulmonary arteries depends on the activation of Rho-kinase
J Appl Physiol 99: 1391-1396, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.00473.2005 [Abstract] [Full Text] [PDF]  

Hiroshi Hasegawa, Romain Meeusen, Sophie Sarre, Marc Diltoer, Maria Francesca Piacentini, and Yvette Michotte

Acute dopamine/norepinephrine reuptake inhibition increases brain and core temperature in rats
J Appl Physiol 99: 1397-1401, 2005. First published May 26, 2005; doi:10.1152/japplphysiol.00435.2005 [Abstract] [Full Text] [PDF]  

Kevin E. Finucane, Janine A. Panizza, and Bhajan Singh

Efficiency of the normal human diaphragm with hyperinflation
J Appl Physiol 99: 1402-1411, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.01165.2004 [Abstract] [Full Text] [PDF]  

Christopher R. Woodman, Mark A. Thompson, James R. Turk, and M. Harold Laughlin

Endurance exercise training improves endothelium-dependent relaxation in brachial arteries from hypercholesterolemic male pigs
J Appl Physiol 99: 1412-1421, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00293.2005 [Abstract] [Full Text] [PDF]  

Titus Kuehne, B. Kelly Gleason, Maythem Saeed, Daniel Turner, Jochen Weil, David F. Teitel, Charles B. Higgins, and Phillip Moore

Combined pulmonary stenosis and insufficiency preserves myocardial contractility in the developing heart of growing swine at midterm follow-up
J Appl Physiol 99: 1422-1427, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00324.2005 [Abstract] [Full Text] [PDF]  

James A. Kuzman, Tracy A. Thomas, Kathryn A. Vogelsang, Suleman Said, Brent E. Anderson, and A. Martin Gerdes

Effects of induced hyperthyroidism in normal and cardiomyopathic hamsters
J Appl Physiol 99: 1428-1433, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00515.2005 [Abstract] [Full Text] [PDF]  

Ümit Kemal Sentürk, Filiz Gündüz, Oktay Kuru, Günnur Koçer, Yasar Gül Özkaya, Akin Yesilkaya, Melek Bor-Küçükatay, Murat Üyüklü, Özlem Yalçin, and Oguz K. Baskurt

Exercise-induced oxidative stress leads hemolysis in sedentary but not trained humans
J Appl Physiol 99: 1434-1441, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.01392.2004 [Abstract] [Full Text] [PDF]  

Naoyuki Hayashi, Satoshi Koba, and Takayoshi Yoshida

Disuse atrophy increases the muscle mechanoreflex in rats
J Appl Physiol 99: 1442-1445, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00180.2005 [Abstract] [Full Text] [PDF]  

Arthur J. Cheng and Charles L. Rice

Fatigue and recovery of power and isometric torque following isotonic knee extensions
J Appl Physiol 99: 1446-1452, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00452.2005 [Abstract] [Full Text] [PDF]  

Graeme R. Polglase, Colin J. Morley, Kelly J. Crossley, Peter Dargaville, Richard Harding, David L. Morgan, and Stuart B. Hooper

Positive end-expiratory pressure differentially alters pulmonary hemodynamics and oxygenation in ventilated, very premature lambs
J Appl Physiol 99: 1453-1461, 2005. First published May 12, 2005; doi:10.1152/japplphysiol.00055.2005 [Abstract] [Full Text] [PDF]  

Nicole D. Paterson, John M. Kowalchuk, and Donald H. Paterson

Effects of prior heavy-intensity exercise during single-leg knee extension on O₂ kinetics and limb blood flow
J Appl Physiol 99: 1462-1470, 2005. First published May 12, 2005; doi:10.1152/japplphysiol.00173.2005 [Abstract] [Full Text] [PDF]  

Coert J. Zuurbier, Cihan Demirci, Anneke Koeman, Hans Vink, and Can Ince

Short-term hyperglycemia increases endothelial glycocalyx permeability and acutely decreases lineal density of capillaries with flowing red blood cells
J Appl Physiol 99: 1471-1476, 2005. First published July 14, 2005; doi:10.1152/japplphysiol.00436.2005 [Abstract] [Full Text] [PDF]  

Laura Bennet, Jenny A. Westgate, Yung-Chi ("Jack") Liu, Guido Wassink, and Alistair J. Gunn

Fetal acidosis and hypotension during repeated umbilical cord occlusions are associated with enhanced chemoreflex responses in near-term fetal sheep
J Appl Physiol 99: 1477-1482, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00431.2005 [Abstract] [Full Text] [PDF]  

Martin V. Sale and John G. Semmler

Age-related differences in corticospinal control during functional isometric contractions in left and right hands
J Appl Physiol 99: 1483-1493, 2005. First published June 9, 2005; doi:10.1152/japplphysiol.00371.2005 [Abstract] [Full Text] [PDF]  

Hui Zhong, Roland R. Roy, Boonclaire Siengthai, and V. Reggie Edgerton

Effects of inactivity on fiber size and myonuclear number in rat soleus muscle
J Appl Physiol 99: 1494-1499, 2005. First published June 30, 2005; doi:10.1152/japplphysiol.00394.2005 [Abstract] [Full Text] [PDF]  

H.-M. Schiøtz Thorud, E. Verburg, P. K. Lunde, T. A. Strømme, I. Sjaastad, and O. M. Sejersted

Temperature-dependent skeletal muscle dysfunction in rats with congestive heart failure
J Appl Physiol 99: 1500-1507, 2005. First published June 2, 2005; doi:10.1152/japplphysiol.00807.2004 [Abstract] [Full Text] [PDF]  

Justin Reis, Lianqin Zhang, Steve Cala, Korinne N. Jew, Lisa C. Mace, Linda Chung, Russell L. Moore, and Yuk-Chow Ng

Expression of phospholemman and its association with Na⁺-K⁺-ATPase in skeletal muscle: effects of aging and exercise training
J Appl Physiol 99: 1508-1515, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.00375.2005 [Abstract] [Full Text] [PDF]  

Yutaka Kano, Danielle J. Padilla, Brad J. Behnke, K. Sue Hageman, Timothy I. Musch, and David C. Poole

Effects of eccentric exercise on microcirculation and microvascular oxygen pressures in rat spinotrapezius muscle
J Appl Physiol 99: 1516-1522, 2005. First published June 30, 2005; doi:10.1152/japplphysiol.00069.2005 [Abstract] [Full Text] [PDF]  

Mette S. Olufsen, Johnny T. Ottesen, Hien T. Tran, Laura M. Ellwein, Lewis A. Lipsitz, and Vera Novak

Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation
J Appl Physiol 99: 1523-1537, 2005. First published April 28, 2005; doi:10.1152/japplphysiol.00177.2005 [Abstract] [Full Text] [PDF]  

M. Tartas, P. Bouyé, A. Koïtka, V. Jaquinandi, L. Tan, J. L. Saumet, and P. Abraham

Cathodal current-induced vasodilation to single application and the amplified response to repeated application in humans rely on aspirin-sensitive mechanisms
J Appl Physiol 99: 1538-1544, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00258.2005 [Abstract] [Full Text] [PDF]  

William B. Farquhar, Erin E. Paul, Allen V. Prettyman, and Michael E. Stillabower

Blood pressure and hemodynamic responses to an acute sodium load in humans
J Appl Physiol 99: 1545-1551, 2005. First published June 23, 2005; doi:10.1152/japplphysiol.00262.2005 [Abstract] [Full Text] [PDF]  

Niels J. Christensen, Martina Heer, Krassimira Ivanova, and Peter Norsk

Sympathetic nervous activity decreases during head-down bed rest but not during microgravity
J Appl Physiol 99: 1552-1557, 2005. First published June 16, 2005; doi:10.1152/japplphysiol.00017.2005 [Abstract] [Full Text] [PDF]  

Jesper Lundbye Jensen, Peter C. D. Marstrand, and Jens B. Nielsen

Motor skill training and strength training are associated with different plastic changes in the central nervous system
J Appl Physiol 99: 1558-1568, 2005. First published May 12, 2005; doi:10.1152/japplphysiol.01408.2004 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

Terry Young, Paul E. Peppard, and Shahrad Taheri

Invited Review  Excess weight and sleep-disordered breathing
J Appl Physiol 99: 1592-1599, 2005; doi:10.1152/japplphysiol.00587.2005 [Abstract] [Full Text] [PDF]  

Sanjay R. Patel

Invited Review  Shared genetic risk factors for obstructive sleep apnea and obesity
J Appl Physiol 99: 1600-1606, 2005; doi:10.1152/japplphysiol.00501.2005 [Abstract] [Full Text] [PDF]  

James E. Fewell, Vienna K. Y. Ng, and Chunfen Zhang

Prior exposure to hypoxic-induced apnea impairs protective responses of newborn rats in an exposure-dependent fashion: influence of normoxic recovery time
J Appl Physiol 99: 1607-1612, 2005. First published June 9, 2005; doi:10.1152/japplphysiol.01267.2004 [Abstract] [Full Text] [PDF]  

Cris A. Slentz, Lori B. Aiken, Joseph A. Houmard, Connie W. Bales, Johanna L. Johnson, Charles J. Tanner, Brian D. Duscha, and William E. Kraus

Inactivity, exercise, and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount
J Appl Physiol 99: 1613-1618, 2005. First published July 7, 2005; doi:10.1152/japplphysiol.00124.2005 [Abstract] [Full Text] [PDF]  

POINT-COUNTERPOINT COMMENTS

David S. Celermajer

Brachial artery FMD with 5-minute distal cuff occlusion—a useful pathophysiological test after all!
J Appl Physiol 99: 1619-1619, 2005; doi:10.1152/japplphysiol.00726.2005 [Abstract] [Full Text] [PDF]  

Beth A. Parker and David N. Proctor

Flow-mediated dilation
J Appl Physiol 99: 1620-1620, 2005; doi:10.1152/japplphysiol.00864.2005 [Abstract] [Full Text] [PDF]  

Clare E. Austin

Flow-mediated dilation does/does not reflect nitric oxide-mediated endothelial function
J Appl Physiol 99: 1621-1621, 2005; doi:10.1152/japplphysiol.00817.2005 [Abstract] [Full Text] [PDF]  

Axel Linke, Sandra Erbs, and Rainer Hambrecht

Flow-mediated vasodilation partially reflects nitric oxide-mediated endothelial function
J Appl Physiol 99: 1622-1622, 2005; doi:10.1152/japplphysiol.00805.2005 [Abstract] [Full Text] [PDF]  

Robinson Joannides and Jeremy Bellien

Flow-mediated dilatation revisited
J Appl Physiol 99: 1623-1623, 2005; doi:10.1152/japplphysiol.00880.2005 [Abstract] [Full Text] [PDF]  

D. Walter Wray and Russell S. Richardson

In FMD, NO is actually "the middle man"
J Appl Physiol 99: 1624-1624, 2005; doi:10.1152/japplphysiol.00875.2005 [Abstract] [Full Text] [PDF]  

Mark A. Creager

Flow-mediated vasodilation is mediated by endothelium-derived nitric oxide
J Appl Physiol 99: 1625-1625, 2005; doi:10.1152/japplphysiol.00829.2005 [Abstract] [Full Text] [PDF]  

Gail D. Thomas

Flow-mediated dilation and biological variability
J Appl Physiol 99: 1626-1626, 2005; doi:10.1152/japplphysiol.00839.2005 [Abstract] [Full Text] [PDF]  

Hirofumi Tanaka

FMD vs. pharmacological approaches for endothelial function
J Appl Physiol 99: 1627-1627, 2005; doi:10.1152/japplphysiol.00387.2005 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR

David T. Martin, Marc J. Quod, Christopher J. Gore, and Edward F. Coyle

Has Armstrong's cycle efficiency improved?
J Appl Physiol 99: 1628-1629, 2005; doi:10.1152/japplphysiol.00507.2005 [Abstract] [Full Text] [PDF]  

Yorck Olaf Schumacher, Stefan Vogt, Kai Roecker, Andreas Schmid, and Edward F. Coyle

Scientific considerations for physiological evaluations of elite athletes
J Appl Physiol 99: 1630-1631, 2005; doi:10.1152/japplphysiol.00563.2005 [Abstract] [Full Text] [PDF]  

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