EDITORIAL

Gary C. Sieck

HIGHLIGHTED TOPIC: Pulmonary Circulation and Hypoxia
J Appl Physiol 98: 1-2, 2005; doi:10.1152/japplphysiol.01123.2004 [Full Text] [PDF]  

INVITED REVIEW

Christian K. Roberts and R. James Barnard

Effects of exercise and diet on chronic disease
J Appl Physiol 98: 3-30, 2005; doi:10.1152/japplphysiol.00852.2004 [Abstract] [Full Text] [PDF]  

INVITED COMMENTARY

B. A. J. Reddi and R. H. S. Carpenter

Venous excess: a new approach to cardiovascular control and its teaching
J Appl Physiol 98: 356-364, 2005. First published August 20, 2004; doi:10.1152/japplphysiol.00535.2004 [Abstract] [Full Text] [PDF]  

HISTORICAL PERSPECTIVES

John B. West

Robert Boyle’s landmark book of 1660 with the first experiments on rarified air
J Appl Physiol 98: 31-39, 2005; doi:10.1152/japplphysiol.00759.2004 [Abstract] [Full Text] [PDF]  

REPORT

Kari K. Kalliokoski, Juhani Knuuti, and Pirjo Nuutila

Relationship between muscle blood flow and oxygen uptake during exercise in endurance-trained and untrained men
J Appl Physiol 98: 380-383, 2005. First published September 3, 2004; doi:10.1152/japplphysiol.01306.2003 [Abstract] [Full Text] [PDF]  

ARTICLES

Ellen M. Evans, Susan B. Racette, Linda R. Peterson, Dennis T. Villareal, Jeffrey S. Greiwe, and John O. Holloszy

Aerobic power and insulin action improve in response to endurance exercise training in healthy 77–87 yr olds
J Appl Physiol 98: 40-45, 2005; doi:10.1152/japplphysiol.00928.2004 [Abstract] [Full Text] [PDF]  

F. Haddad, K. M. Baldwin, and P. A. Tesch

Pretranslational markers of contractile protein expression in human skeletal muscle: effect of limb unloading plus resistance exercise
J Appl Physiol 98: 46-52, 2005. First published August 6, 2004; doi:10.1152/japplphysiol.00553.2004 [Abstract] [Full Text] [PDF]  

Luciana L. Farias, Débora S. Faffe, Débora G. Xisto, Maria Cristina E. Santana, Roberta Lassance, Luiz Felipe M. Prota, Marcelo B. Amato, Marcelo M. Morales, Walter A. Zin, and Patricia R. M. Rocco

Positive end-expiratory pressure prevents lung mechanical stress caused by recruitment/derecruitment
J Appl Physiol 98: 53-61, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00118.2004 [Abstract] [Full Text] [PDF]  

Werner Lang and Rolf Zander

Prediction of dilutional acidosis based on the revised classical dilution concept for bicarbonate
J Appl Physiol 98: 62-71, 2005; doi:10.1152/japplphysiol.00292.2004 [Abstract] [Full Text] [PDF]  

Zoran Valic, John B. Buckwalter, and Philip S. Clifford

Muscle blood flow response to contraction: influence of venous pressure
J Appl Physiol 98: 72-76, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00151.2004 [Abstract] [Full Text] [PDF]  

Hong Kan, Dale Birkle, Abnash C. Jain, Conard Failinger, Sherry Xie, and Mitchell S. Finkel

p38 MAP kinase inhibitor reverses stress-induced cardiac myocyte dysfunction
J Appl Physiol 98: 77-82, 2005. First published October 1, 2004; doi:10.1152/japplphysiol.00171.2004 [Abstract] [Full Text] [PDF]  

C. Reboul, S. Tanguy, J. M. Juan, M. Dauzat, and P. Obert

Cardiac remodeling and functional adaptations consecutive to altitude training in rats: implications for sea level aerobic performance
J Appl Physiol 98: 83-92, 2005. First published July 30, 2004; doi:10.1152/japplphysiol.00214.2004 [Abstract] [Full Text] [PDF]  

Anne K. Hansen, Christian P. Fischer, Peter Plomgaard, Jesper Løvind Andersen, Bengt Saltin, and Bente Klarlund Pedersen

Skeletal muscle adaptation: training twice every second day vs. training once daily
J Appl Physiol 98: 93-99, 2005. First published September 10, 2004; doi:10.1152/japplphysiol.00163.2004 [Abstract] [Full Text] [PDF]  

Tanya L. Pehleman, Sandra J. Peters, George J. F. Heigenhauser, and Lawrence L. Spriet

Enzymatic regulation of glucose disposal in human skeletal muscle after a high-fat, low-carbohydrate diet
J Appl Physiol 98: 100-107, 2005. First published August 13, 2004; doi:10.1152/japplphysiol.00686.2004 [Abstract] [Full Text] [PDF]  

Jorge A. Guzman, Mathew S. Dikin, and James A. Kruse

Lingual, splanchnic, and systemic hemodynamic and carbon dioxide tension changes during endotoxic shock and resuscitation
J Appl Physiol 98: 108-113, 2005. First published July 30, 2004; doi:10.1152/japplphysiol.00243.2004 [Abstract] [Full Text] [PDF]  

Stephen Chad Kanick, William J. Doyle, Samir N. Ghadiali, and William J. Federspiel

On morphometric measurement of oxygen diffusing capacity in middle ear gas exchange
J Appl Physiol 98: 114-119, 2005. First published August 13, 2004; doi:10.1152/japplphysiol.00203.2004 [Abstract] [Full Text] [PDF]  

Kevin G. Keenan, Dario Farina, Katrina S. Maluf, Roberto Merletti, and Roger M. Enoka

Influence of amplitude cancellation on the simulated surface electromyogram
J Appl Physiol 98: 120-131, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00894.2004 [Abstract] [Full Text] [PDF]  

Sean Walsh, Joseph M. Zmuda, Jane A. Cauley, Patrick R. Shea, E. Jeffrey Metter, Ben F. Hurley, Robert E. Ferrell, and Stephen M. Roth

Androgen receptor CAG repeat polymorphism is associated with fat-free mass in men
J Appl Physiol 98: 132-137, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00537.2004 [Abstract] [Full Text] [PDF]  

Kwang-Jin Kim, Zea Borok, Carsten Ehrhardt, Brigham C. Willis, Claus-Michael Lehr, and Edward D. Crandall

Estimation of paracellular conductance of primary rat alveolar epithelial cell monolayers
J Appl Physiol 98: 138-143, 2005. First published July 23, 2004; doi:10.1152/japplphysiol.00478.2004 [Abstract] [Full Text] [PDF]  

R. Arieli, O. Ertracht, I. Oster, A. Vitenstein, and Y. Adir

Effects of nitrogen and helium on CNS oxygen toxicity in the rat
J Appl Physiol 98: 144-150, 2005. First published August 20, 2004; doi:10.1152/japplphysiol.00506.2004 [Abstract] [Full Text] [PDF]  

Jorge M. Serrador, Farzaneh A. Sorond, Mitul Vyas, Margaret Gagnon, Ikechukwu D. Iloputaife, and Lewis A. Lipsitz

Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains
J Appl Physiol 98: 151-159, 2005. First published September 10, 2004; doi:10.1152/japplphysiol.00471.2004 [Abstract] [Full Text] [PDF]  

Michelle C. Venables, Juul Achten, and Asker E. Jeukendrup

Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study
J Appl Physiol 98: 160-167, 2005. First published August 27, 2004; doi:10.1152/japplphysiol.00662.2003 [Abstract] [Full Text] [PDF]  

Dustin S. Hittel, William E. Kraus, Chuck J. Tanner, Joseph A. Houmard, and Eric P. Hoffman

Exercise training increases electron and substrate shuttling proteins in muscle of overweight men and women with the metabolic syndrome
J Appl Physiol 98: 168-179, 2005. First published September 3, 2004; doi:10.1152/japplphysiol.00331.2004 [Abstract] [Full Text] [PDF]  

Nausherwan K. Burki, Wheeler J. Dale, and Lu-Yuan Lee

Intravenous adenosine and dyspnea in humans
J Appl Physiol 98: 180-185, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00913.2004 [Abstract] [Full Text] [PDF]  

R. J. Aughey, C. J. Gore, A. G. Hahn, A. P. Garnham, S. A. Clark, A. C. Petersen, A. D. Roberts, and M. J. McKenna

Chronic intermittent hypoxia and incremental cycling exercise independently depress muscle in vitro maximal Na⁺-K⁺-ATPase activity in well-trained athletes
J Appl Physiol 98: 186-192, 2005. First published March 19, 2004; doi:10.1152/japplphysiol.01335.2003 [Abstract] [Full Text] [PDF]  

David N. Proctor, Khoi U. Le, and Samuel J. Ridout

Age and regional specificity of peak limb vascular conductance in men
J Appl Physiol 98: 193-202, 2005. First published September 3, 2004; doi:10.1152/japplphysiol.00704.2004 [Abstract] [Full Text] [PDF]  

Christian K. Roberts, R. James Barnard, Ram K. Sindhu, Michael Jurczak, Ashkan Ehdaie, and Nosratola D. Vaziri

A high-fat, refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression
J Appl Physiol 98: 203-210, 2005. First published August 27, 2004; doi:10.1152/japplphysiol.00463.2004 [Abstract] [Full Text] [PDF]  

John K. Petrella, Jeong-su Kim, S. Craig Tuggle, Samuel R. Hall, and Marcas M. Bamman

Age differences in knee extension power, contractile velocity, and fatigability
J Appl Physiol 98: 211-220, 2005. First published September 3, 2004; doi:10.1152/japplphysiol.00294.2004 [Abstract] [Full Text] [PDF]  

Christopher I. Morse, Jeanette M. Thom, Karen M. Birch, and Marco V. Narici

Tendon elongation influences the amplitude of interpolated doublets in the assessment of activation in elderly men
J Appl Physiol 98: 221-226, 2005. First published September 3, 2004; doi:10.1152/japplphysiol.00774.2004 [Abstract] [Full Text] [PDF]  

Jos. J. de Koning, Carl Foster, Joanne Lampen, Floor Hettinga, and Maarten F. Bobbert

Experimental evaluation of the power balance model of speed skating
J Appl Physiol 98: 227-233, 2005; doi:10.1152/japplphysiol.01095.2003 [Abstract] [Full Text] [PDF]  

Richard A. Meiss and Ramana M. Pidaparti

Active and passive components in the length-dependent stiffness of tracheal smooth muscle during isotonic shortening
J Appl Physiol 98: 234-241, 2005. First published August 27, 2004; doi:10.1152/japplphysiol.00574.2004 [Abstract] [Full Text] [PDF]  

Kristy M. Ainslie, Jeffrey S. Garanich, Randal O. Dull, and John M. Tarbell

Vascular smooth muscle cell glycocalyx influences shear stress-mediated contractile response
J Appl Physiol 98: 242-249, 2005. First published August 20, 2004; doi:10.1152/japplphysiol.01006.2003 [Abstract] [Full Text] [PDF]  

Trent Stellingwerff, Lee Glazier, Matthew J. Watt, Paul J. LeBlanc, George J. F. Heigenhauser, and Lawrence L. Spriet

Effects of hyperoxia on skeletal muscle carbohydrate metabolism during transient and steady-state exercise
J Appl Physiol 98: 250-256, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00897.2004 [Abstract] [Full Text] [PDF]  

R. Bryan S. Klassen, Patricia L. Allen, Vecihi Batuman, Kimberly Crenshaw, and Timothy G. Hammond

Light chains are a ligand for megalin
J Appl Physiol 98: 257-263, 2005. First published July 30, 2004; doi:10.1152/japplphysiol.01090.2003 [Abstract] [Full Text] [PDF]  

Bruce M. Damon and John C. Gore

Physiological basis of muscle functional MRI: predictions using a computer model
J Appl Physiol 98: 264-273, 2005. First published August 27, 2004; doi:10.1152/japplphysiol.00369.2004 [Abstract] [Full Text] [PDF]  

Bhajan Singh, Janine A. Panizza, and Kevin E. Finucane

Diaphragm electromyogram root mean square response to hypercapnia and its intersubject and day-to-day variation
J Appl Physiol 98: 274-281, 2005. First published September 10, 2004; doi:10.1152/japplphysiol.01380.2003 [Abstract] [Full Text] [PDF]  

Yoshichika Yoshioka, Hiroshi Oikawa, Shigeru Ehara, Takashi Inoue, Akira Ogawa, Yoshiyuki Kanbara, and Manabu Kubokawa

Noninvasive measurement of temperature and fractional dissociation of imidazole in human lower leg muscles using ¹H-nuclear magnetic resonance spectroscopy
J Appl Physiol 98: 282-287, 2005. First published September 24, 2004; doi:10.1152/japplphysiol.00437.2004 [Abstract] [Full Text] [PDF]  

Redouane Fodil, Lydia Brugel-Ribere, Céline Croce, Gabriela Sbirlea-Apiou, Christian Larger, Jean-François Papon, Christophe Delclaux, André Coste, Daniel Isabey, and Bruno Louis

Inspiratory flow in the nose: a model coupling flow and vasoerectile tissue distensibility
J Appl Physiol 98: 288-295, 2005. First published August 27, 2004; doi:10.1152/japplphysiol.00625.2004 [Abstract] [Full Text] [PDF]  

L. J. Rubin, L. Magliola, X. Feng, A. W. Jones, and C. C. Hale

Metabolic activation of AMP kinase in vascular smooth muscle
J Appl Physiol 98: 296-306, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00075.2004 [Abstract] [Full Text] [PDF]  

Neeti Pathare, Glenn A. Walter, Jennifer E. Stevens, Zhaohui Yang, Enyi Okerke, John D. Gibbs, John L. Esterhai, Mark T. Scarborough, C. Parker Gibbs, H. Lee Sweeney, and Krista Vandenborne

Changes in inorganic phosphate and force production in human skeletal muscle after cast immobilization
J Appl Physiol 98: 307-314, 2005. First published August 27, 2004; doi:10.1152/japplphysiol.00612.2004 [Abstract] [Full Text] [PDF]  

Timothy P. Gavin, Howard W. Stallings, III, Kevin A. Zwetsloot, Lenna M. Westerkamp, Nicholas A. Ryan, Rebecca A. Moore, Walter E. Pofahl, and Robert C. Hickner

Lower capillary density but no difference in VEGF expression in obese vs. lean young skeletal muscle in humans
J Appl Physiol 98: 315-321, 2005. First published August 6, 2004; doi:10.1152/japplphysiol.00353.2004 [Abstract] [Full Text] [PDF]  

Stephen P. Chen, Beiyun Zhou, Brigham C. Willis, Argelia J. Sandoval, Janice M. Liebler, Kwang-Jin Kim, David K. Ann, Edward D. Crandall, and Zea Borok

Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells
J Appl Physiol 98: 322-328, 2005. First published September 10, 2004; doi:10.1152/japplphysiol.00681.2004 [Abstract] [Full Text] [PDF]  

Daniel Miller, Kevin Forrester, Catherine Leonard, Paul Salo, and Robert C. Bray

ACL deficiency impairs the vasoconstrictive efficacy of neuropeptide Y and phenylephrine in articular tissues: a laser speckle perfusion imaging study
J Appl Physiol 98: 329-333, 2005. First published September 3, 2004; doi:10.1152/japplphysiol.00514.2004 [Abstract] [Full Text] [PDF]  

Jeong-su Kim, Kenneth W. Hinchcliff, Mamoru Yamaguchi, Laurie A. Beard, Chad D. Markert, and Steven T. Devor

Exercise training increases oxidative capacity and attenuates exercise-induced ultrastructural damage in skeletal muscle of aged horses
J Appl Physiol 98: 334-342, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00172.2003 [Abstract] [Full Text] [PDF]  

Renaud Tamisier, Amit Anand, Luz M. Nieto, David Cunnington, and J. Woodrow Weiss

Arterial pressure and muscle sympathetic nerve activity are increased after two hours of sustained but not cyclic hypoxia in healthy humans
J Appl Physiol 98: 343-349, 2005. First published September 24, 2004; doi:10.1152/japplphysiol.00495.2004 [Abstract] [Full Text] [PDF]  

Erin A. Turvey, George J. F. Heigenhauser, Michelle Parolin, and Sandra J. Peters

Elevated n-3 fatty acids in a high-fat diet attenuate the increase in PDH kinase activity but not PDH activity in human skeletal muscle
J Appl Physiol 98: 350-355, 2005. First published September 17, 2004; doi:10.1152/japplphysiol.00604.2004 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY

B. Matrot, E. Durand, S. Dauger, G. Vardon, C. Gaultier, and J. Gallego

Automatic classification of activity and apneas using whole body plethysmography in newborn mice
J Appl Physiol 98: 365-370, 2005; doi:10.1152/japplphysiol.00803.2004 [Abstract] [Full Text] [PDF]  

Tomoji Mashimo, Birger Voigt, Takashi Kuramoto, and Tadao Serikawa

Rat Phenome Project: The untapped potential of existing rat strains
J Appl Physiol 98: 371-379, 2005; doi:10.1152/japplphysiol.01006.2004 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

John T. Reeves and Robert F. Grover

Historical Perspective  Insights by Peruvian scientists into the pathogenesis of human chronic hypoxic pulmonary hypertension
J Appl Physiol 98: 384-389, 2005; doi:10.1152/japplphysiol.00677.2004 [Abstract] [Full Text] [PDF]  

Rohit Moudgil, Evangelos D. Michelakis, and Stephen L. Archer

Invited Review  Hypoxic pulmonary vasoconstriction
J Appl Physiol 98: 390-403, 2005; doi:10.1152/japplphysiol.00733.2004 [Abstract] [Full Text] [PDF]  

Gregory B. Waypa and Paul T. Schumacker

Invited Review  Hypoxic pulmonary vasoconstriction: redox events in oxygen sensing
J Appl Physiol 98: 404-414, 2005; doi:10.1152/japplphysiol.00722.2004 [Abstract] [Full Text] [PDF]  

Joseph R. H. Mauban, Carmelle V. Remillard, and Jason X.-J. Yuan

Invited Review  Hypoxic pulmonary vasoconstriction: role of ion channels
J Appl Physiol 98: 415-420, 2005; doi:10.1152/japplphysiol.00732.2004 [Abstract] [Full Text] [PDF]  

CORRIGENDA

Corrigendum
J Appl Physiol 98: 421-421, 2005; doi:10.1152/japplphysiol.01180.2004 [Full Text] [PDF]  

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