INVITED EDITORIAL

Joost G. van den Aardweg

Respiratory variability after opioids: see it happen
J Appl Physiol 106: 1029-1030, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.00155.2009 [Full Text] [PDF]  

Philip N. Ainslie

Have a safe night: intimate protection against cerebral hyperperfusion during REM sleep
J Appl Physiol 106: 1031-1033, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.00091.2009 [Full Text] [PDF]  

H. Thomas Robertson

Does hypoxic vasoconstriction influence the normal distribution of human pulmonary blood flow?
J Appl Physiol 106: 1034-1035, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.00015.2009 [Full Text] [PDF]  

Nancy R. Rodriguez

Making room for protein in approaches to muscle recovery from endurance exercise
J Appl Physiol 106: 1036-1037, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.00046.2009 [Full Text] [PDF]  

ARTICLES

G. D. Mitsis, R. J. M. Governo, R. Rogers, and K. T. S. Pattinson

The effect of remifentanil on respiratory variability, evaluated with dynamic modeling
J Appl Physiol 106: 1038-1049, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.90769.2008 [Abstract] [Full Text] [PDF]  

Priscila A. Cassaglia, Robert I. Griffiths, and Adrian M. Walker

Cerebral sympathetic nerve activity has a major regulatory role in the cerebral circulation in REM sleep
J Appl Physiol 106: 1050-1056, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91349.2008 [Abstract] [Full Text] [PDF]  

T. J. Arai, A. C. Henderson, D. J. Dubowitz, D. L. Levin, P. J. Friedman, R. B. Buxton, G. K. Prisk, and S. R. Hopkins

Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans
J Appl Physiol 106: 1057-1064, 2009. First published December 4, 2008; doi:10.1152/japplphysiol.90759.2008 [Abstract] [Full Text] [PDF]  

Noortje T. L. Van Duijnhoven, Thomas W. J. Janssen, Daniel J. Green, Christopher T. Minson, Maria T. E. Hopman, and Dick H. J. Thijssen

Effect of functional electrostimulation on impaired skin vasodilator responses to local heating in spinal cord injury
J Appl Physiol 106: 1065-1071, 2009. First published February 19, 2009; doi:10.1152/japplphysiol.91611.2008 [Abstract] [Full Text] [PDF]  

Steven W. Copp, Robert T. Davis, David C. Poole, and Timothy I. Musch

Reproducibility of endurance capacity and O_2peak in male Sprague-Dawley rats
J Appl Physiol 106: 1072-1078, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91566.2008 [Abstract] [Full Text] [PDF]  

Sudip Bajpeyi, Charles J. Tanner, Cris A. Slentz, Brian D. Duscha, Jennifer S. McCartney, Robert C. Hickner, William E. Kraus, and Joseph A. Houmard

Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation
J Appl Physiol 106: 1079-1085, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.91262.2008 [Abstract] [Full Text] [PDF]  

Yvonne Mounier, Vincent Tiffreau, Valérie Montel, Bruno Bastide, and Laurence Stevens

Phenotypical transitions and Ca²⁺ activation properties in human muscle fibers: effects of a 60-day bed rest and countermeasures
J Appl Physiol 106: 1086-1099, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.90695.2008 [Abstract] [Full Text] [PDF]  

A. Guadalupe-Grau, J. Perez-Gomez, H. Olmedillas, J. Chavarren, C. Dorado, A. Santana, J. A. Serrano-Sanchez, and J. A. L. Calbet

Strength training combined with plyometric jumps in adults: sex differences in fat-bone axis adaptations
J Appl Physiol 106: 1100-1111, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.91469.2008 [Abstract] [Full Text] [PDF]  

Gary J. Hodges, Caroline Chiu, Wojciech A. Kosiba, Kun Zhao, and John M. Johnson

The effect of microdialysis needle trauma on cutaneous vascular responses in humans
J Appl Physiol 106: 1112-1118, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.91508.2008 [Abstract] [Full Text] [PDF]  

Tadashi Suga, Koichi Okita, Noriteru Morita, Takashi Yokota, Kagami Hirabayashi, Masahiro Horiuchi, Shingo Takada, Tomohiro Takahashi, Masashi Omokawa, Shintaro Kinugawa, and Hiroyuki Tsutsui

Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction
J Appl Physiol 106: 1119-1124, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.90368.2008 [Abstract] [Full Text] [PDF]  

Jian Cui, Manabu Shibasaki, Scott L. Davis, David A. Low, David M. Keller, and Craig G. Crandall

Whole body heat stress attenuates baroreflex control of muscle sympathetic nerve activity during postexercise muscle ischemia
J Appl Physiol 106: 1125-1131, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.00135.2008 [Abstract] [Full Text] [PDF]  

Fangping Chen, Hong Kan, Gerry Hobbs, and Mitchell S. Finkel

p38 MAP kinase inhibitor reverses stress-induced myocardial dysfunction in vivo
J Appl Physiol 106: 1132-1141, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.90542.2008 [Abstract] [Full Text] [PDF]  

You Shuei Lin, Ruei-Lung Lin, Mauo-Ying Bien, Ching-Yin Ho, and Yu Ru Kou

Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors
J Appl Physiol 106: 1142-1152, 2009. First published January 8, 2009; doi:10.1152/japplphysiol.91229.2008 [Abstract] [Full Text] [PDF]  

Andrew W. Subudhi, Brittany R. Miramon, Matthew E. Granger, and Robert C. Roach

Frontal and motor cortex oxygenation during maximal exercise in normoxia and hypoxia
J Appl Physiol 106: 1153-1158, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91475.2008 [Abstract] [Full Text] [PDF]  

Scott Trappe, David Costill, Philip Gallagher, Andrew Creer, Jim R. Peters, Harlan Evans, Danny A. Riley, and Robert H. Fitts

Exercise in space: human skeletal muscle after 6 months aboard the International Space Station
J Appl Physiol 106: 1159-1168, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91578.2008 [Abstract] [Full Text] [PDF]  

Huub Maas, Robert J. Gregor, Emma F. Hodson-Tole, Brad J. Farrell, and Boris I. Prilutsky

Distinct muscle fascicle length changes in feline medial gastrocnemius and soleus muscles during slope walking
J Appl Physiol 106: 1169-1180, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.01306.2007 [Abstract] [Full Text] [PDF]  

Jennifer L. Robbins, Brian D. Duscha, Daniel R. Bensimhon, Karlman Wasserman, James E. Hansen, Joseph A. Houmard, Brian H. Annex, and William E. Kraus

A sex-specific relationship between capillary density and anaerobic threshold
J Appl Physiol 106: 1181-1186, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.90947.2008 [Abstract] [Full Text] [PDF]  

Vernon G. Coffey, Henriette Pilegaard, Andrew P. Garnham, Brendan J. O'Brien, and John A. Hawley

Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle
J Appl Physiol 106: 1187-1197, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.91221.2008 [Abstract] [Full Text] [PDF]  

Graydon H. Raymer, Howard J. Green, Don A. Ranney, Greg D. Marsh, and R. Terry Thompson

Muscle metabolism and acid-base status during exercise in forearm work-related myalgia measured with ³¹P-MRS
J Appl Physiol 106: 1198-1206, 2009. First published December 26, 2008; doi:10.1152/japplphysiol.90925.2008 [Abstract] [Full Text] [PDF]  

Peter J. Fagenholz, Jonathan A. Gutman, Alice F. Murray, Vicki E. Noble, Carlos A. Camargo, Jr., and N. Stuart Harris

Optic nerve sheath diameter correlates with the presence and severity of acute mountain sickness: evidence for increased intracranial pressure
J Appl Physiol 106: 1207-1211, 2009. First published December 31, 2008; doi:10.1152/japplphysiol.01188.2007 [Abstract] [Full Text] [PDF]  

Qiuli Liu, Charles Fehring, Timothy F. Lowry, and Margaret T. T. Wong-Riley

Postnatal development of metabolic rate during normoxia and acute hypoxia in rats: implication for a sensitive period
J Appl Physiol 106: 1212-1222, 2009. First published December 31, 2008; doi:10.1152/japplphysiol.90949.2008 [Abstract] [Full Text] [PDF]  

Z. Song, K. A. Harris, and B. T. Thach

Laryngeal constriction during hypoxic gasping and its role in improving autoresuscitation in two mouse strains
J Appl Physiol 106: 1223-1226, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.91192.2008 [Abstract] [Full Text] [PDF]  

Kevin S. Heffernan, Jacob J. Sosnoff, Edward Ofori, Sae Young Jae, Tracy Baynard, Scott R. Collier, Stella Goulopoulou, Arturo Figueroa, Jeffrey A. Woods, Kenneth H. Pitetti, and Bo Fernhall

Complexity of force output during static exercise in individuals with Down syndrome
J Appl Physiol 106: 1227-1233, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.90555.2008 [Abstract] [Full Text] [PDF]  

Ivan T. Demchenko, Alex Ruehle, Barry W. Allen, Richard D. Vann, and Claude A. Piantadosi

Phosphodiesterase-5 inhibitors oppose hyperoxic vasoconstriction and accelerate seizure development in rats exposed to hyperbaric oxygen
J Appl Physiol 106: 1234-1242, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91407.2008 [Abstract] [Full Text] [PDF]  

Thomas Kjeld, Frank C. Pott, and Niels H. Secher

Facial immersion in cold water enhances cerebral blood velocity during breath-hold exercise in humans
J Appl Physiol 106: 1243-1248, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.90370.2008 [Abstract] [Full Text] [PDF]  

Anthony D. Kay and Anthony J. Blazevich

Moderate-duration static stretch reduces active and passive plantar flexor moment but not Achilles tendon stiffness or active muscle length
J Appl Physiol 106: 1249-1256, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91476.2008 [Abstract] [Full Text] [PDF]  

Neil R. Gleason, George Gallos, Yi Zhang, and Charles W. Emala

The GABA_A agonist muscimol attenuates induced airway constriction in guinea pigs in vivo
J Appl Physiol 106: 1257-1263, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91314.2008 [Abstract] [Full Text] [PDF]  

Andreas D. Flouris and Stephen S. Cheung

Influence of thermal balance on cold-induced vasodilation
J Appl Physiol 106: 1264-1271, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91426.2008 [Abstract] [Full Text] [PDF]  

Didier Delignières and Kjerstin Torre

Fractal dynamics of human gait: a reassessment of the 1996 data of Hausdorff et al.
J Appl Physiol 106: 1272-1279, 2009. First published February 19, 2009; doi:10.1152/japplphysiol.90757.2008 [Abstract] [Full Text] [PDF]  

Chun-Hong Shao, Xander H. T. Wehrens, Todd A. Wyatt, Sheeva Parbhu, George J. Rozanski, Kaushik P. Patel, and Keshore R. Bidasee

Exercise training during diabetes attenuates cardiac ryanodine receptor dysregulation
J Appl Physiol 106: 1280-1292, 2009. First published January 8, 2009; doi:10.1152/japplphysiol.91280.2008 [Abstract] [Full Text] [PDF]  

Lisa Campana, Jennifer Kenyon, Sanaz Zhalehdoust-Sani, Yang-Sheng Tzeng, Yanping Sun, Mitchell Albert, and Kenneth R. Lutchen

Probing airway conditions governing ventilation defects in asthma via hyperpolarized MRI image functional modeling
J Appl Physiol 106: 1293-1300, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91428.2008 [Abstract] [Full Text] [PDF]  

César Osorio-Fuentealba, Juan Antonio Valdés, Denise Riquelme, Jorge Hidalgo, Cecilia Hidalgo, and María Angélica Carrasco

Hypoxia stimulates via separate pathways ERK phosphorylation and NF-B activation in skeletal muscle cells in primary culture
J Appl Physiol 106: 1301-1310, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91224.2008 [Abstract] [Full Text] [PDF]  

Rosa Burdi, Jean-François Rolland, Bodvael Fraysse, Karina Litvinova, Anna Cozzoli, Viviana Giannuzzi, Antonella Liantonio, Giulia Maria Camerino, Valeriana Sblendorio, Roberta Francesca Capogrosso, Beniamino Palmieri, Francesca Andreetta, Paolo Confalonieri, Leonarda De Benedictis, Monica Montagnani, and Annamaria De Luca

Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests
J Appl Physiol 106: 1311-1324, 2009. First published January 8, 2009; doi:10.1152/japplphysiol.90985.2008 [Abstract] [Full Text] [PDF]  

Carolina D. Garciarena, Claudia I. Caldiz, Enrique L. Portiansky, Gladys E. Chiappe de Cingolani, and Irene L. Ennis

Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart
J Appl Physiol 106: 1325-1331, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91300.2008 [Abstract] [Full Text] [PDF]  

T. Finni, V. Kovanen, P. H. A. Ronkainen, E. Pöllänen, G. R. Bashford, J. Kaprio, M. Alén, U. M. Kujala, and S. Sipilä

Combination of hormone replacement therapy and high physical activity is associated with differences in Achilles tendon size in monozygotic female twin pairs
J Appl Physiol 106: 1332-1337, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.91439.2008 [Abstract] [Full Text] [PDF]  

Marisa Garcia and Ghassan S. Kassab

Right coronary artery becomes stiffer with increase in elastin and collagen in right ventricular hypertrophy
J Appl Physiol 106: 1338-1346, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.90592.2008 [Abstract] [Full Text] [PDF]  

Graeme R. Polglase, Stuart B. Hooper, Andrew W. Gill, Beth J. Allison, Carryn J. McLean, Ilias Nitsos, J. Jane Pillow, and Martin Kluckow

Cardiovascular and pulmonary consequences of airway recruitment in preterm lambs
J Appl Physiol 106: 1347-1355, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91445.2008 [Abstract] [Full Text] [PDF]  

Arne Yndestad, Karl-Otto Larsen, Erik Øie, Thor Ueland, Camilla Smith, Bente Halvorsen, Ivar Sjaastad, Ole Henning Skjønsberg, Turid M. Pedersen, Ole-Gunnar Anfinsen, Jan Kristian Damås, Geir Christensen, Pål Aukrust, and Arne K. Andreassen

Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol 106: 1356-1364, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.90719.2008 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

Blake B. Rasmussen and Erik A. Richter

The balancing act between the cellular processes of protein synthesis and breakdown: exercise as a model to understand the molecular mechanisms regulating muscle mass
J Appl Physiol 106: 1365-1366, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.00081.2009 [Full Text] [PDF]  

Mitsunori Miyazaki and Karyn A. Esser

Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals
J Appl Physiol 106: 1367-1373, 2009. First published November 26, 2008; doi:10.1152/japplphysiol.91355.2008 [Abstract] [Full Text] [PDF]  

Micah J. Drummond, Hans C. Dreyer, Christopher S. Fry, Erin L. Glynn, and Blake B. Rasmussen

Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling
J Appl Physiol 106: 1374-1384, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91397.2008 [Abstract] [Full Text] [PDF]  

Mette Hansen, Mads Kongsgaard, Lars Holm, Dorthe Skovgaard, S. Peter Magnusson, Klaus Qvortrup, Jytte O. Larsen, Per Aagaard, Morten Dahl, Annette Serup, Jan Frystyk, Allan Flyvbjerg, Henning Langberg, and Michael Kjaer

Effect of estrogen on tendon collagen synthesis, tendon structural characteristics, and biomechanical properties in postmenopausal women
J Appl Physiol 106: 1385-1393, 2009. First published October 16, 2008; doi:10.1152/japplphysiol.90935.2008 [Abstract] [Full Text] [PDF]  

Krista R. Howarth, Natalie A. Moreau, Stuart M. Phillips, and Martin J. Gibala

Coingestion of protein with carbohydrate during recovery from endurance exercise stimulates skeletal muscle protein synthesis in humans
J Appl Physiol 106: 1394-1402, 2009. First published November 26, 2008; doi:10.1152/japplphysiol.90333.2008 [Abstract] [Full Text] [PDF]  

Micah J. Drummond, Mitsunori Miyazaki, Hans C. Dreyer, Bart Pennings, Shaheen Dhanani, Elena Volpi, Karyn A. Esser, and Blake B. Rasmussen

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis
J Appl Physiol 106: 1403-1411, 2009. First published September 11, 2008; doi:10.1152/japplphysiol.90842.2008 [Abstract] [Full Text] [PDF]  

Jörgen Tannerstedt, William Apró, and Eva Blomstrand

Maximal lengthening contractions induce different signaling responses in the type I and type II fibers of human skeletal muscle
J Appl Physiol 106: 1412-1418, 2009. First published December 26, 2008; doi:10.1152/japplphysiol.91243.2008 [Abstract] [Full Text] [PDF]  

Maarit Lehti, Riikka Kivelä, Paavo Komi, Jyrki Komulainen, Heikki Kainulainen, and Heikki Kyröläinen

Effects of fatiguing jumping exercise on mRNA expression of titin-complex proteins and calpains
J Appl Physiol 106: 1419-1424, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.90660.2008 [Abstract] [Full Text] [PDF]  

Anisha A. Gupte, Gregory L. Bomhoff, Jill K. Morris, Brittany K. Gorres, and Paige C. Geiger

Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats
J Appl Physiol 106: 1425-1434, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91210.2008 [Abstract] [Full Text] [PDF]  

M. Hansen, B. F. Miller, L. Holm, S. Doessing, S. G. Petersen, D. Skovgaard, J. Frystyk, A. Flyvbjerg, S. Koskinen, J. Pingel, M. Kjaer, and H. Langberg

Effect of administration of oral contraceptives in vivo on collagen synthesis in tendon and muscle connective tissue in young women
J Appl Physiol 106: 1435-1443, 2009. First published October 9, 2008; doi:10.1152/japplphysiol.90933.2008 [Abstract] [Full Text] [PDF]  

Bruce D. Spiess

Perfluorocarbon emulsions as a promising technology: a review of tissue and vascular gas dynamics
J Appl Physiol 106: 1444-1452, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.90995.2008 [Abstract] [Full Text] [PDF]  

R. Arieli, E. Boaron, and A. Abramovich

Combined effect of denucleation and denitrogenation on the risk of decompression sickness in rats
J Appl Physiol 106: 1453-1458, 2009. First published February 19, 2009; doi:10.1152/japplphysiol.91146.2008 [Abstract] [Full Text] [PDF]  

R. T. Mahon, H. M. Dainer, M. G. Gibellato, and S. E. Soutiere

Short oxygen prebreathe periods reduce or prevent severe decompression sickness in a 70-kg swine saturation model
J Appl Physiol 106: 1459-1463, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91058.2008 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR

G. Mahe, P. Rousseau, J. L. Saumet, and P. Abraham

About "Chronic low-dose aspirin therapy attenuates reflex cutaneous vasodilatation in middle-aged humans"
J Appl Physiol 106: 1471-1471, 2009; doi:10.1152/japplphysiol.91653.2008 [Full Text] [PDF]  

Lacy A. Holowatz and W. Larry Kenney

Reply to Mahe, Rousseau, Saumet, and Abraham
J Appl Physiol 106: 1472-1472, 2009; doi:10.1152/japplphysiol.00038.2009 [Full Text] [PDF]  

Søren Brage, Vincent T. van Hees, and Niels Brage

Intergeneration accelerometer differences and correction for on-board frequency-based filtering
J Appl Physiol 106: 1473-1473, 2009; doi:10.1152/japplphysiol.00019.2009 [Full Text] [PDF]  

Megan Rothney and Kong Chen

Reply to Brage, Van Hees, and Brage
J Appl Physiol 106: 1474-1475, 2009; doi:10.1152/japplphysiol.00048.2009 [Full Text] [PDF]  

VIEWPOINT

Eugene Nattie and Aihua Li

Central chemoreception is a complex system function that involves multiple brain stem sites
J Appl Physiol 106: 1464-1466, 2009. First published May 8, 2008; doi:10.1152/japplphysiol.00112.2008 [Full Text] [PDF]  

Luiz G. S. Branco, Thiago S. Moreira, Patrice G. Guyenet, Peter M. Lalley, A. Kawai, Robert W. Putnam, Nancy L. Chamberlin, Clifford B. Saper, Alexander V. Gourine, Mitsuko Kanamaru, and Ikuo Homma

Commentaries on Viewpoint: Central chemoreception is a complex system function that involves multiple brain stem sites
J Appl Physiol 106: 1467-1470, 2009; doi:10.1152/japplphysiol.00057.2009 [Full Text] [PDF]  

ARTICLES

G. D. Mitsis, R. J. M. Governo, R. Rogers, and K. T. S. Pattinson

The effect of remifentanil on respiratory variability, evaluated with dynamic modeling
J Appl Physiol 106: 1038-1049, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.90769.2008 [Abstract] [Full Text] [PDF]  

Priscila A. Cassaglia, Robert I. Griffiths, and Adrian M. Walker

Cerebral sympathetic nerve activity has a major regulatory role in the cerebral circulation in REM sleep
J Appl Physiol 106: 1050-1056, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91349.2008 [Abstract] [Full Text] [PDF]  

T. J. Arai, A. C. Henderson, D. J. Dubowitz, D. L. Levin, P. J. Friedman, R. B. Buxton, G. K. Prisk, and S. R. Hopkins

Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans
J Appl Physiol 106: 1057-1064, 2009. First published December 4, 2008; doi:10.1152/japplphysiol.90759.2008 [Abstract] [Full Text] [PDF]  

Noortje T. L. Van Duijnhoven, Thomas W. J. Janssen, Daniel J. Green, Christopher T. Minson, Maria T. E. Hopman, and Dick H. J. Thijssen

Effect of functional electrostimulation on impaired skin vasodilator responses to local heating in spinal cord injury
J Appl Physiol 106: 1065-1071, 2009. First published February 19, 2009; doi:10.1152/japplphysiol.91611.2008 [Abstract] [Full Text] [PDF]  

Steven W. Copp, Robert T. Davis, David C. Poole, and Timothy I. Musch

Reproducibility of endurance capacity and O_2peak in male Sprague-Dawley rats
J Appl Physiol 106: 1072-1078, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91566.2008 [Abstract] [Full Text] [PDF]  

Sudip Bajpeyi, Charles J. Tanner, Cris A. Slentz, Brian D. Duscha, Jennifer S. McCartney, Robert C. Hickner, William E. Kraus, and Joseph A. Houmard

Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation
J Appl Physiol 106: 1079-1085, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.91262.2008 [Abstract] [Full Text] [PDF]  

Yvonne Mounier, Vincent Tiffreau, Valérie Montel, Bruno Bastide, and Laurence Stevens

Phenotypical transitions and Ca²⁺ activation properties in human muscle fibers: effects of a 60-day bed rest and countermeasures
J Appl Physiol 106: 1086-1099, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.90695.2008 [Abstract] [Full Text] [PDF]  

A. Guadalupe-Grau, J. Perez-Gomez, H. Olmedillas, J. Chavarren, C. Dorado, A. Santana, J. A. Serrano-Sanchez, and J. A. L. Calbet

Strength training combined with plyometric jumps in adults: sex differences in fat-bone axis adaptations
J Appl Physiol 106: 1100-1111, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.91469.2008 [Abstract] [Full Text] [PDF]  

Gary J. Hodges, Caroline Chiu, Wojciech A. Kosiba, Kun Zhao, and John M. Johnson

The effect of microdialysis needle trauma on cutaneous vascular responses in humans
J Appl Physiol 106: 1112-1118, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.91508.2008 [Abstract] [Full Text] [PDF]  

Tadashi Suga, Koichi Okita, Noriteru Morita, Takashi Yokota, Kagami Hirabayashi, Masahiro Horiuchi, Shingo Takada, Tomohiro Takahashi, Masashi Omokawa, Shintaro Kinugawa, and Hiroyuki Tsutsui

Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction
J Appl Physiol 106: 1119-1124, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.90368.2008 [Abstract] [Full Text] [PDF]  

Jian Cui, Manabu Shibasaki, Scott L. Davis, David A. Low, David M. Keller, and Craig G. Crandall

Whole body heat stress attenuates baroreflex control of muscle sympathetic nerve activity during postexercise muscle ischemia
J Appl Physiol 106: 1125-1131, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.00135.2008 [Abstract] [Full Text] [PDF]  

Fangping Chen, Hong Kan, Gerry Hobbs, and Mitchell S. Finkel

p38 MAP kinase inhibitor reverses stress-induced myocardial dysfunction in vivo
J Appl Physiol 106: 1132-1141, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.90542.2008 [Abstract] [Full Text] [PDF]  

You Shuei Lin, Ruei-Lung Lin, Mauo-Ying Bien, Ching-Yin Ho, and Yu Ru Kou

Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors
J Appl Physiol 106: 1142-1152, 2009. First published January 8, 2009; doi:10.1152/japplphysiol.91229.2008 [Abstract] [Full Text] [PDF]  

Andrew W. Subudhi, Brittany R. Miramon, Matthew E. Granger, and Robert C. Roach

Frontal and motor cortex oxygenation during maximal exercise in normoxia and hypoxia
J Appl Physiol 106: 1153-1158, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91475.2008 [Abstract] [Full Text] [PDF]  

Scott Trappe, David Costill, Philip Gallagher, Andrew Creer, Jim R. Peters, Harlan Evans, Danny A. Riley, and Robert H. Fitts

Exercise in space: human skeletal muscle after 6 months aboard the International Space Station
J Appl Physiol 106: 1159-1168, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91578.2008 [Abstract] [Full Text] [PDF]  

Huub Maas, Robert J. Gregor, Emma F. Hodson-Tole, Brad J. Farrell, and Boris I. Prilutsky

Distinct muscle fascicle length changes in feline medial gastrocnemius and soleus muscles during slope walking
J Appl Physiol 106: 1169-1180, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.01306.2007 [Abstract] [Full Text] [PDF]  

Jennifer L. Robbins, Brian D. Duscha, Daniel R. Bensimhon, Karlman Wasserman, James E. Hansen, Joseph A. Houmard, Brian H. Annex, and William E. Kraus

A sex-specific relationship between capillary density and anaerobic threshold
J Appl Physiol 106: 1181-1186, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.90947.2008 [Abstract] [Full Text] [PDF]  

Vernon G. Coffey, Henriette Pilegaard, Andrew P. Garnham, Brendan J. O'Brien, and John A. Hawley

Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle
J Appl Physiol 106: 1187-1197, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.91221.2008 [Abstract] [Full Text] [PDF]  

Graydon H. Raymer, Howard J. Green, Don A. Ranney, Greg D. Marsh, and R. Terry Thompson

Muscle metabolism and acid-base status during exercise in forearm work-related myalgia measured with ³¹P-MRS
J Appl Physiol 106: 1198-1206, 2009. First published December 26, 2008; doi:10.1152/japplphysiol.90925.2008 [Abstract] [Full Text] [PDF]  

Peter J. Fagenholz, Jonathan A. Gutman, Alice F. Murray, Vicki E. Noble, Carlos A. Camargo, Jr., and N. Stuart Harris

Optic nerve sheath diameter correlates with the presence and severity of acute mountain sickness: evidence for increased intracranial pressure
J Appl Physiol 106: 1207-1211, 2009. First published December 31, 2008; doi:10.1152/japplphysiol.01188.2007 [Abstract] [Full Text] [PDF]  

Qiuli Liu, Charles Fehring, Timothy F. Lowry, and Margaret T. T. Wong-Riley

Postnatal development of metabolic rate during normoxia and acute hypoxia in rats: implication for a sensitive period
J Appl Physiol 106: 1212-1222, 2009. First published December 31, 2008; doi:10.1152/japplphysiol.90949.2008 [Abstract] [Full Text] [PDF]  

Z. Song, K. A. Harris, and B. T. Thach

Laryngeal constriction during hypoxic gasping and its role in improving autoresuscitation in two mouse strains
J Appl Physiol 106: 1223-1226, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.91192.2008 [Abstract] [Full Text] [PDF]  

Kevin S. Heffernan, Jacob J. Sosnoff, Edward Ofori, Sae Young Jae, Tracy Baynard, Scott R. Collier, Stella Goulopoulou, Arturo Figueroa, Jeffrey A. Woods, Kenneth H. Pitetti, and Bo Fernhall

Complexity of force output during static exercise in individuals with Down syndrome
J Appl Physiol 106: 1227-1233, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.90555.2008 [Abstract] [Full Text] [PDF]  

Ivan T. Demchenko, Alex Ruehle, Barry W. Allen, Richard D. Vann, and Claude A. Piantadosi

Phosphodiesterase-5 inhibitors oppose hyperoxic vasoconstriction and accelerate seizure development in rats exposed to hyperbaric oxygen
J Appl Physiol 106: 1234-1242, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91407.2008 [Abstract] [Full Text] [PDF]  

Thomas Kjeld, Frank C. Pott, and Niels H. Secher

Facial immersion in cold water enhances cerebral blood velocity during breath-hold exercise in humans
J Appl Physiol 106: 1243-1248, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.90370.2008 [Abstract] [Full Text] [PDF]  

Anthony D. Kay and Anthony J. Blazevich

Moderate-duration static stretch reduces active and passive plantar flexor moment but not Achilles tendon stiffness or active muscle length
J Appl Physiol 106: 1249-1256, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91476.2008 [Abstract] [Full Text] [PDF]  

Neil R. Gleason, George Gallos, Yi Zhang, and Charles W. Emala

The GABA_A agonist muscimol attenuates induced airway constriction in guinea pigs in vivo
J Appl Physiol 106: 1257-1263, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91314.2008 [Abstract] [Full Text] [PDF]  

Andreas D. Flouris and Stephen S. Cheung

Influence of thermal balance on cold-induced vasodilation
J Appl Physiol 106: 1264-1271, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91426.2008 [Abstract] [Full Text] [PDF]  

Didier Delignières and Kjerstin Torre

Fractal dynamics of human gait: a reassessment of the 1996 data of Hausdorff et al.
J Appl Physiol 106: 1272-1279, 2009. First published February 19, 2009; doi:10.1152/japplphysiol.90757.2008 [Abstract] [Full Text] [PDF]  

Chun-Hong Shao, Xander H. T. Wehrens, Todd A. Wyatt, Sheeva Parbhu, George J. Rozanski, Kaushik P. Patel, and Keshore R. Bidasee

Exercise training during diabetes attenuates cardiac ryanodine receptor dysregulation
J Appl Physiol 106: 1280-1292, 2009. First published January 8, 2009; doi:10.1152/japplphysiol.91280.2008 [Abstract] [Full Text] [PDF]  

Lisa Campana, Jennifer Kenyon, Sanaz Zhalehdoust-Sani, Yang-Sheng Tzeng, Yanping Sun, Mitchell Albert, and Kenneth R. Lutchen

Probing airway conditions governing ventilation defects in asthma via hyperpolarized MRI image functional modeling
J Appl Physiol 106: 1293-1300, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91428.2008 [Abstract] [Full Text] [PDF]  

César Osorio-Fuentealba, Juan Antonio Valdés, Denise Riquelme, Jorge Hidalgo, Cecilia Hidalgo, and María Angélica Carrasco

Hypoxia stimulates via separate pathways ERK phosphorylation and NF-B activation in skeletal muscle cells in primary culture
J Appl Physiol 106: 1301-1310, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91224.2008 [Abstract] [Full Text] [PDF]  

Rosa Burdi, Jean-François Rolland, Bodvael Fraysse, Karina Litvinova, Anna Cozzoli, Viviana Giannuzzi, Antonella Liantonio, Giulia Maria Camerino, Valeriana Sblendorio, Roberta Francesca Capogrosso, Beniamino Palmieri, Francesca Andreetta, Paolo Confalonieri, Leonarda De Benedictis, Monica Montagnani, and Annamaria De Luca

Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests
J Appl Physiol 106: 1311-1324, 2009. First published January 8, 2009; doi:10.1152/japplphysiol.90985.2008 [Abstract] [Full Text] [PDF]  

Carolina D. Garciarena, Claudia I. Caldiz, Enrique L. Portiansky, Gladys E. Chiappe de Cingolani, and Irene L. Ennis

Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart
J Appl Physiol 106: 1325-1331, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91300.2008 [Abstract] [Full Text] [PDF]  

T. Finni, V. Kovanen, P. H. A. Ronkainen, E. Pöllänen, G. R. Bashford, J. Kaprio, M. Alén, U. M. Kujala, and S. Sipilä

Combination of hormone replacement therapy and high physical activity is associated with differences in Achilles tendon size in monozygotic female twin pairs
J Appl Physiol 106: 1332-1337, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.91439.2008 [Abstract] [Full Text] [PDF]  

Marisa Garcia and Ghassan S. Kassab

Right coronary artery becomes stiffer with increase in elastin and collagen in right ventricular hypertrophy
J Appl Physiol 106: 1338-1346, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.90592.2008 [Abstract] [Full Text] [PDF]  

Graeme R. Polglase, Stuart B. Hooper, Andrew W. Gill, Beth J. Allison, Carryn J. McLean, Ilias Nitsos, J. Jane Pillow, and Martin Kluckow

Cardiovascular and pulmonary consequences of airway recruitment in preterm lambs
J Appl Physiol 106: 1347-1355, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.91445.2008 [Abstract] [Full Text] [PDF]  

Arne Yndestad, Karl-Otto Larsen, Erik Øie, Thor Ueland, Camilla Smith, Bente Halvorsen, Ivar Sjaastad, Ole Henning Skjønsberg, Turid M. Pedersen, Ole-Gunnar Anfinsen, Jan Kristian Damås, Geir Christensen, Pål Aukrust, and Arne K. Andreassen

Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol 106: 1356-1364, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.90719.2008 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

Blake B. Rasmussen and Erik A. Richter

The balancing act between the cellular processes of protein synthesis and breakdown: exercise as a model to understand the molecular mechanisms regulating muscle mass
J Appl Physiol 106: 1365-1366, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.00081.2009 [Full Text] [PDF]  

Mitsunori Miyazaki and Karyn A. Esser

Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals
J Appl Physiol 106: 1367-1373, 2009. First published November 26, 2008; doi:10.1152/japplphysiol.91355.2008 [Abstract] [Full Text] [PDF]  

Micah J. Drummond, Hans C. Dreyer, Christopher S. Fry, Erin L. Glynn, and Blake B. Rasmussen

Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling
J Appl Physiol 106: 1374-1384, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.91397.2008 [Abstract] [Full Text] [PDF]  

Mette Hansen, Mads Kongsgaard, Lars Holm, Dorthe Skovgaard, S. Peter Magnusson, Klaus Qvortrup, Jytte O. Larsen, Per Aagaard, Morten Dahl, Annette Serup, Jan Frystyk, Allan Flyvbjerg, Henning Langberg, and Michael Kjaer

Effect of estrogen on tendon collagen synthesis, tendon structural characteristics, and biomechanical properties in postmenopausal women
J Appl Physiol 106: 1385-1393, 2009. First published October 16, 2008; doi:10.1152/japplphysiol.90935.2008 [Abstract] [Full Text] [PDF]  

Krista R. Howarth, Natalie A. Moreau, Stuart M. Phillips, and Martin J. Gibala

Coingestion of protein with carbohydrate during recovery from endurance exercise stimulates skeletal muscle protein synthesis in humans
J Appl Physiol 106: 1394-1402, 2009. First published November 26, 2008; doi:10.1152/japplphysiol.90333.2008 [Abstract] [Full Text] [PDF]  

Micah J. Drummond, Mitsunori Miyazaki, Hans C. Dreyer, Bart Pennings, Shaheen Dhanani, Elena Volpi, Karyn A. Esser, and Blake B. Rasmussen

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis
J Appl Physiol 106: 1403-1411, 2009. First published September 11, 2008; doi:10.1152/japplphysiol.90842.2008 [Abstract] [Full Text] [PDF]  

Jörgen Tannerstedt, William Apró, and Eva Blomstrand

Maximal lengthening contractions induce different signaling responses in the type I and type II fibers of human skeletal muscle
J Appl Physiol 106: 1412-1418, 2009. First published December 26, 2008; doi:10.1152/japplphysiol.91243.2008 [Abstract] [Full Text] [PDF]  

Maarit Lehti, Riikka Kivelä, Paavo Komi, Jyrki Komulainen, Heikki Kainulainen, and Heikki Kyröläinen

Effects of fatiguing jumping exercise on mRNA expression of titin-complex proteins and calpains
J Appl Physiol 106: 1419-1424, 2009. First published January 15, 2009; doi:10.1152/japplphysiol.90660.2008 [Abstract] [Full Text] [PDF]  

Anisha A. Gupte, Gregory L. Bomhoff, Jill K. Morris, Brittany K. Gorres, and Paige C. Geiger

Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats
J Appl Physiol 106: 1425-1434, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91210.2008 [Abstract] [Full Text] [PDF]  

M. Hansen, B. F. Miller, L. Holm, S. Doessing, S. G. Petersen, D. Skovgaard, J. Frystyk, A. Flyvbjerg, S. Koskinen, J. Pingel, M. Kjaer, and H. Langberg

Effect of administration of oral contraceptives in vivo on collagen synthesis in tendon and muscle connective tissue in young women
J Appl Physiol 106: 1435-1443, 2009. First published October 9, 2008; doi:10.1152/japplphysiol.90933.2008 [Abstract] [Full Text] [PDF]  

Bruce D. Spiess

Perfluorocarbon emulsions as a promising technology: a review of tissue and vascular gas dynamics
J Appl Physiol 106: 1444-1452, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.90995.2008 [Abstract] [Full Text] [PDF]  

R. Arieli, E. Boaron, and A. Abramovich

Combined effect of denucleation and denitrogenation on the risk of decompression sickness in rats
J Appl Physiol 106: 1453-1458, 2009. First published February 19, 2009; doi:10.1152/japplphysiol.91146.2008 [Abstract] [Full Text] [PDF]  

R. T. Mahon, H. M. Dainer, M. G. Gibellato, and S. E. Soutiere

Short oxygen prebreathe periods reduce or prevent severe decompression sickness in a 70-kg swine saturation model
J Appl Physiol 106: 1459-1463, 2009. First published January 29, 2009; doi:10.1152/japplphysiol.91058.2008 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR

G. Mahe, P. Rousseau, J. L. Saumet, and P. Abraham

About "Chronic low-dose aspirin therapy attenuates reflex cutaneous vasodilatation in middle-aged humans"
J Appl Physiol 106: 1471-1471, 2009; doi:10.1152/japplphysiol.91653.2008 [Full Text] [PDF]  

Lacy A. Holowatz and W. Larry Kenney

Reply to Mahe, Rousseau, Saumet, and Abraham
J Appl Physiol 106: 1472-1472, 2009; doi:10.1152/japplphysiol.00038.2009 [Full Text] [PDF]  

Søren Brage, Vincent T. van Hees, and Niels Brage

Intergeneration accelerometer differences and correction for on-board frequency-based filtering
J Appl Physiol 106: 1473-1473, 2009; doi:10.1152/japplphysiol.00019.2009 [Full Text] [PDF]  

Megan Rothney and Kong Chen

Reply to Brage, Van Hees, and Brage
J Appl Physiol 106: 1474-1475, 2009; doi:10.1152/japplphysiol.00048.2009 [Full Text] [PDF]  

INVITED EDITORIAL

Joost G. van den Aardweg

Respiratory variability after opioids: see it happen
J Appl Physiol 106: 1029-1030, 2009. First published February 12, 2009; doi:10.1152/japplphysiol.00155.2009 [Full Text] [PDF]  

Philip N. Ainslie

Have a safe night: intimate protection against cerebral hyperperfusion during REM sleep
J Appl Physiol 106: 1031-1033, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.00091.2009 [Full Text] [PDF]  

H. Thomas Robertson

Does hypoxic vasoconstriction influence the normal distribution of human pulmonary blood flow?
J Appl Physiol 106: 1034-1035, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.00015.2009 [Full Text] [PDF]  

Nancy R. Rodriguez

Making room for protein in approaches to muscle recovery from endurance exercise
J Appl Physiol 106: 1036-1037, 2009. First published January 22, 2009; doi:10.1152/japplphysiol.00046.2009 [Full Text] [PDF]  

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