REPORT

Shawn G. Hayes, Jennifer L. McCord, and Marc P. Kaufman

Role played by P2X and P2Y receptors in evoking the muscle chemoreflex
J Appl Physiol 104: 538-541, 2008. First published December 6, 2007; doi:10.1152/japplphysiol.00929.2007 [Abstract] [Full Text] [PDF]  

ARTICLES

Julien Boissiere, Véronique Eder, Marie-Christine Machet, Daniel Courteix, and Pierre Bonnet

Moderate exercise training does not worsen left ventricle remodeling and function in untreated severe hypertensive rats
J Appl Physiol 104: 321-327, 2008. First published November 21, 2007; doi:10.1152/japplphysiol.00442.2007 [Abstract] [Full Text] [PDF]  

Martin J. Truijens, Ferran A. Rodríguez, Nathan E. Townsend, James Stray-Gundersen, Christopher J. Gore, and Benjamin D. Levine

The effect of intermittent hypobaric hypoxic exposure and sea level training on submaximal economy in well-trained swimmers and runners
J Appl Physiol 104: 328-337, 2008. First published November 29, 2007; doi:10.1152/japplphysiol.01324.2006 [Abstract] [Full Text] [PDF]  

Arata Tabuchi, Michael Mertens, Hermann Kuppe, Axel R. Pries, and Wolfgang M. Kuebler

Intravital microscopy of the murine pulmonary microcirculation
J Appl Physiol 104: 338-346, 2008. First published November 15, 2007; doi:10.1152/japplphysiol.00348.2007 [Abstract] [Full Text] [PDF] [Supplemental Video]  

Deborah L. Enns and Peter M. Tiidus

Estrogen influences satellite cell activation and proliferation following downhill running in rats
J Appl Physiol 104: 347-353, 2008. First published December 20, 2007; doi:10.1152/japplphysiol.00128.2007 [Abstract] [Full Text] [PDF]  

Takashige Miyahara, Kazutoshi Hamanaka, David S. Weber, Mircea Anghelescu, James R. Frost, Judy A. King, and James C. Parker

Cytosolic phospholipase A₂ and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs
J Appl Physiol 104: 354-362, 2008. First published November 15, 2007; doi:10.1152/japplphysiol.00959.2006 [Abstract] [Full Text] [PDF]  

C. Rantzau, M. Christopher, and F. P. Alford

Contrasting effects of exercise, AICAR, and increased fatty acid supply on in vivo and skeletal muscle glucose metabolism
J Appl Physiol 104: 363-370, 2008. First published November 21, 2007; doi:10.1152/japplphysiol.00500.2007 [Abstract] [Full Text] [PDF]  

Louise Deldicque, Philip Atherton, Rekha Patel, Daniel Theisen, Henri Nielens, Michael J. Rennie, and Marc Francaux

Effects of resistance exercise with and without creatine supplementation on gene expression and cell signaling in human skeletal muscle
J Appl Physiol 104: 371-378, 2008. First published November 29, 2007; doi:10.1152/japplphysiol.00873.2007 [Abstract] [Full Text] [PDF]  

Michele C. Battié, Esko Levalahti, Tapio Videman, Kim Burton, and Jaakko Kaprio

Heritability of lumbar flexibility and the role of disc degeneration and body weight
J Appl Physiol 104: 379-385, 2008. First published November 29, 2007; doi:10.1152/japplphysiol.01009.2007 [Abstract] [Full Text] [PDF]  

Carlos L. del Rio, Patrick I. McConnell, Monica Kukielka, Roger Dzwonczyk, Bradley D. Clymer, Michael B. Howie, and George E. Billman

Electrotonic remodeling following myocardial infarction in dogs susceptible and resistant to sudden cardiac death
J Appl Physiol 104: 386-393, 2008. First published November 29, 2007; doi:10.1152/japplphysiol.01106.2007 [Abstract] [Full Text] [PDF]  

Ronald L. Sorkness, Eugene R. Bleecker, William W. Busse, William J. Calhoun, Mario Castro, Kian Fan Chung, Douglas Curran-Everett, Serpil C. Erzurum, Benjamin M. Gaston, Elliot Israel, Nizar N. Jarjour, Wendy C. Moore, Stephen P. Peters, W. Gerald Teague, Sally E. Wenzel, for the National Heart, Lung, and Blood Institute Severe Asthma Research Program

Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation
J Appl Physiol 104: 394-403, 2008. First published November 8, 2007; doi:10.1152/japplphysiol.00329.2007 [Abstract] [Full Text] [PDF]  

D. J. Collier, A. H. Nickol, J. S. Milledge, H. J. A. van Ruiten, C. J. Collier, E. R. Swenson, Avijit Datta, and C. B. Wolff

Alveolar PCO₂ oscillations and ventilation at sea level and at high altitude
J Appl Physiol 104: 404-415, 2008. First published October 25, 2007; doi:10.1152/japplphysiol.00166.2007 [Abstract] [Full Text] [PDF]  

Y. Kasashima, T. Takahashi, H. L. Birch, R. K. W. Smith, and A. E. Goodship

Can exercise modulate the maturation of functionally different immature tendons in the horse?
J Appl Physiol 104: 416-422, 2008. First published December 13, 2007; doi:10.1152/japplphysiol.00379.2007 [Abstract] [Full Text] [PDF]  

Dimitri Leduc, Matteo Cappello, Pierre Alain Gevenois, and André De Troyer

Mechanics of the canine diaphragm in ascites: a CT study
J Appl Physiol 104: 423-428, 2008. First published December 13, 2007; doi:10.1152/japplphysiol.00884.2007 [Abstract] [Full Text] [PDF]  

D. M. Thomson, S. T. Herway, N. Fillmore, H. Kim, J. D. Brown, J. R. Barrow, and W. W. Winder

AMP-activated protein kinase phosphorylates transcription factors of the CREB family
J Appl Physiol 104: 429-438, 2008. First published December 6, 2007; doi:10.1152/japplphysiol.00900.2007 [Abstract] [Full Text] [PDF]  

David G. Edwards, Corey R. Mastin, and Robert W. Kenefick

Wave reflection and central aortic pressure are increased in response to static and dynamic muscle contraction at comparable workloads
J Appl Physiol 104: 439-445, 2008. First published December 13, 2007; doi:10.1152/japplphysiol.00541.2007 [Abstract] [Full Text] [PDF]  

Miriam P. Bal, Willem B. de Vries, Matthijs F. M. van Oosterhout, Jan Baan, Ernst E. van der Wall, Frank van Bel, and Paul Steendijk

Long-term cardiovascular effects of neonatal dexamethasone treatment: hemodynamic follow-up by left ventricular pressure-volume loops in rats
J Appl Physiol 104: 446-450, 2008. First published December 13, 2007; doi:10.1152/japplphysiol.00951.2007 [Abstract] [Full Text] [PDF]  

Mary P. Miles, Jan M. Andring, Sherri D. Pearson, Lindsay K. Gordon, Christine Kasper, Christopher M. Depner, and Jessy R. Kidd

Diurnal variation, response to eccentric exercise, and association of inflammatory mediators with muscle damage variables
J Appl Physiol 104: 451-458, 2008. First published December 13, 2007; doi:10.1152/japplphysiol.00572.2007 [Abstract] [Full Text] [PDF]  

Srinivasan Rajaraman, Andrei V. Gribok, Nancy J. Wesensten, Thomas J. Balkin, and Jaques Reifman

Individualized performance prediction of sleep-deprived individuals with the two-process model
J Appl Physiol 104: 459-468, 2008. First published December 13, 2007; doi:10.1152/japplphysiol.00877.2007 [Abstract] [Full Text] [PDF] [Supplemental Material]  

Christopher I. Morse, Keith Tolfrey, Jeanette M. Thom, Vasilios Vassilopoulos, Constantinos N. Maganaris, and Marco V. Narici

Gastrocnemius muscle specific force in boys and men
J Appl Physiol 104: 469-474, 2008. First published December 20, 2007; doi:10.1152/japplphysiol.00697.2007 [Abstract] [Full Text] [PDF]  

Babs R. Soller, Ye Yang, Olusola O. Soyemi, Kathy L. Ryan, Caroline A. Rickards, J. Matthias Walz, Stephen O. Heard, and Victor A. Convertino

Noninvasively determined muscle oxygen saturation is an early indicator of central hypovolemia in humans
J Appl Physiol 104: 475-481, 2008. First published November 15, 2007; doi:10.1152/japplphysiol.00600.2007 [Abstract] [Full Text] [PDF]  

Craig D. Steinback and Marc J. Poulin

Cardiovascular and cerebrovascular responses to acute isocapnic and poikilocapnic hypoxia in humans
J Appl Physiol 104: 482-489, 2008. First published November 29, 2007; doi:10.1152/japplphysiol.00553.2007 [Abstract] [Full Text] [PDF]  

Philip N. Ainslie, Shigehiko Ogoh, Katie Burgess, Leo Celi, Ken McGrattan, Karen Peebles, Carissa Murrell, Prajan Subedi, and Keith R. Burgess

Differential effects of acute hypoxia and high altitude on cerebral blood flow velocity and dynamic cerebral autoregulation: alterations with hyperoxia
J Appl Physiol 104: 490-498, 2008. First published November 29, 2007; doi:10.1152/japplphysiol.00778.2007 [Abstract] [Full Text] [PDF]  

Jiro Terada, Akira Nakamura, Wei Zhang, Masashi Yanagisawa, Takayuki Kuriyama, Yasuichiro Fukuda, and Tomoyuki Kuwaki

Ventilatory long-term facilitation in mice can be observed during both sleep and wake periods and depends on orexin
J Appl Physiol 104: 499-507, 2008. First published November 21, 2007; doi:10.1152/japplphysiol.00919.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Dean A. Sewell, Tristan M. Robinson, and Paul L. Greenhaff

Creatine supplementation does not affect human skeletal muscle glycogen content in the absence of prior exercise
J Appl Physiol 104: 508-512, 2008. First published November 21, 2007; doi:10.1152/japplphysiol.00787.2007 [Abstract] [Full Text] [PDF]  

Matt M. Riordan and Sándor J. Kovács

Elucidation of spatially distinct compensatory mechanisms in diastole: radial compensation for impaired longitudinal filling in left ventricular hypertrophy
J Appl Physiol 104: 513-520, 2008. First published November 21, 2007; doi:10.1152/japplphysiol.00848.2007 [Abstract] [Full Text] [PDF]  

Stephen J. Lai-Fook, Pamela K. Houtz, and Yih-Loong Lai

End-expiratory and tidal volumes measured in conscious mice using single projection x-ray images
J Appl Physiol 104: 521-533, 2008. First published September 13, 2007; doi:10.1152/japplphysiol.00729.2007 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY

Ulla Ramer Mikkelsen, Ida Carøe Helmark, Michael Kjær, and Henning Langberg

Prostaglandin synthesis can be inhibited locally by infusion of NSAIDS through microdialysis catheters in human skeletal muscle
J Appl Physiol 104: 534-537, 2008. First published December 13, 2007; doi:10.1152/japplphysiol.01016.2007 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

Janet L. Taylor and Simon C. Gandevia

A comparison of central aspects of fatigue in submaximal and maximal voluntary contractions
J Appl Physiol 104: 542-550, 2008. First published November 21, 2007; doi:10.1152/japplphysiol.01053.2007 [Abstract] [Full Text] [PDF]  

Robert H. Fitts

The cross-bridge cycle and skeletal muscle fatigue
J Appl Physiol 104: 551-558, 2008. First published December 27, 2007; doi:10.1152/japplphysiol.01200.2007 [Abstract] [Full Text] [PDF]  

POINT-COUNTERPOINT

Arne K. Andreassen

Point:Counterpoint: Cardiac denervation does/does not play a major role in exercise limitation after heart transplantation
J Appl Physiol 104: 559-560, 2008. First published July 5, 2007; doi:10.1152/japplphysiol.00694.2007 [Full Text] [PDF]  

R. Richard, J. Zoll, B. Mettauer, F. Piquard, and B. Geny

Counterpoint: Cardiac denervation does not play a major role in exercise limitation after heart transplantation
J Appl Physiol 104: 560-562, 2008; doi:10.1152/japplphysiol.00694.2007a [Full Text] [PDF]  

Rebuttal from Dr. Andreassen
J Appl Physiol 104: 562-563, 2008; doi:10.1152/japplphysiol.00694.2007b [Full Text] [PDF]  

Rebuttal from Drs. Richard, Zoll, Mettauer, Piquard, and Geny
J Appl Physiol 104: 563-564, 2008; doi:10.1152/japplphysiol.00694.2007c [Full Text] [PDF]  

Bernard Geny, Ruddy Richard, Joffrey Zoll, Anne Charloux, and Francois Piquard

Last Word on Point:Counterpoint: Cardiac denervation does/does not play a major role in exercise limitation after heart transplantation
J Appl Physiol 104: 568-568, 2008; doi:10.1152/japplphysiol.01159.2007 [Full Text] [PDF]  

POINT-COUNTERPOINT COMMENTS

Claudio Marconi, Mauro Marzorati, Paolo Cerretelli, Roy J. Shephard, E. Sankaranarayanan Prakash, Bruno Grassi, Francesca Lanfranconi, Simone Porcelli, Alessandra Ferri, Emma Borrelli, Etienne Delacretaz, Hildegard Tanner, David M. Kaye, and Murray D. Esler

Cardiac denervation does/does not play a major role in exercise limitation after heart transplantation
J Appl Physiol 104: 565-567, 2008; doi:10.1152/japplphysiol.01225.2007 [Full Text] [PDF]  

LETTERS TO THE EDITOR

K. L. Dorrington

Master dysnatremia equation for Gibbs-Donnan equilibrium and plasma sodium concentration: proof or spoof?
J Appl Physiol 104: 569-569, 2008; doi:10.1152/japplphysiol.01167.2007 [Full Text] [PDF]  

Minhtri K. Nguyen and Ira Kurtz

Reply from Nguyen and Kurtz
J Appl Physiol 104: 570-572, 2008; doi:10.1152/japplphysiol.01277.2007 [Full Text] [PDF]  

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