INVITED EDITORIAL

Anne B. Loucks

New animal model opens opportunities for research on the female athlete triad
J Appl Physiol 103: 1467-1468, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00907.2007 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY

Luxi Xia, Tracey Damon, Mary M. Niblock, Donald Bartlett, Jr., and J. C. Leiter

Unilateral microdialysis of gabazine in the dorsal medulla reverses thermal prolongation of the laryngeal chemoreflex in decerebrate piglets
J Appl Physiol 103: 1864-1872, 2007. First published September 6, 2007; doi:10.1152/japplphysiol.00524.2007 [Abstract] [Full Text] [PDF]  

ARTICLES

Nancy M. DiMarco, Lyn Dart, and Charlotte (Barney) Sanborn

Modified activity-stress paradigm in an animal model of the female athlete triad
J Appl Physiol 103: 1469-1478, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.01137.2005 [Abstract] [Full Text] [PDF]  

J. C. López-Ramos, P. J. Yi, L. Eleore, N. Madroñal, A. Rueda, and J. M. Delgado-García

Classical eyeblink conditioning during acute hypobaric hypoxia is improved in acclimatized mice and involves Fos expression in selected brain areas
J Appl Physiol 103: 1479-1487, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00384.2007 [Abstract] [Full Text] [PDF]  

Jeong-su Kim, John K. Petrella, James M. Cross, and Marcas M. Bamman

Load-mediated downregulation of myostatin mRNA is not sufficient to promote myofiber hypertrophy in humans: a cluster analysis
J Appl Physiol 103: 1488-1495, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.01194.2006 [Abstract] [Full Text] [PDF]  

Connie C. W. Hsia, Robert L. Johnson, Jr., D. Merrill Dane, Eugene Y. Wu, Aaron S. Estrera, Harrieth E. Wagner, and Peter D. Wagner

The canine spleen in oxygen transport: gas exchange and hemodynamic responses to splenectomy
J Appl Physiol 103: 1496-1505, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00281.2007 [Abstract] [Full Text] [PDF]  

R. El Hasnaoui-Saadani, R. Cardenas Alayza, T. Launay, A. Pichon, P. Quidu, M. Beaudry, F. Léon-Velarde, J. P. Richalet, A. Duvallet, and F. Favret

Brain stem NO modulates ventilatory acclimatization to hypoxia in mice
J Appl Physiol 103: 1506-1512, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00486.2007 [Abstract] [Full Text] [PDF]  

A. Nedergaard, K. Vissing, K. Overgaard, M. Kjaer, and P. Schjerling

Expression patterns of atrogenic and ubiquitin proteasome component genes with exercise: effect of different loading patterns and repeated exercise bouts
J Appl Physiol 103: 1513-1522, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.01445.2006 [Abstract] [Full Text] [PDF]  

Ferran A. Rodríguez, Martin J. Truijens, Nathan E. Townsend, James Stray-Gundersen, Christopher J. Gore, and Benjamin D. Levine

Performance of runners and swimmers after four weeks of intermittent hypobaric hypoxic exposure plus sea level training
J Appl Physiol 103: 1523-1535, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.01320.2006 [Abstract] [Full Text] [PDF]  

Ole Hartvig Mortensen, Peter Plomgaard, Christian P. Fischer, Anne K. Hansen, Henriette Pilegaard, and Bente Klarlund Pedersen

PGC-1 is downregulated by training in human skeletal muscle: no effect of training twice every second day vs. once daily on expression of the PGC-1 family
J Appl Physiol 103: 1536-1542, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00575.2007 [Abstract] [Full Text] [PDF]  

Steven B. Heymsfield, Douglas Childers, Joel Beetsch, David B. Allison, and Angelo Pietrobelli

Body size and human energy requirements: reduced mass-specific resting energy expenditure in tall adults
J Appl Physiol 103: 1543-1550, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00461.2007 [Abstract] [Full Text] [PDF]  

Apiradee Thammanomai, Arnab Majumdar, Erzsébet Bartolák-Suki, and Béla Suki

Effects of reduced tidal volume ventilation on pulmonary function in mice before and after acute lung injury
J Appl Physiol 103: 1551-1559, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00006.2007 [Abstract] [Full Text] [PDF]  

Geng-Qing Song and Jiande D. Z. Chen

Synchronized gastric electrical stimulation improves delayed gastric emptying in nonobese mice with diabetic gastroparesis
J Appl Physiol 103: 1560-1564, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00319.2007 [Abstract] [Full Text] [PDF]  

Anthony J. Blazevich, Dale Cannavan, David R. Coleman, and Sara Horne

Influence of concentric and eccentric resistance training on architectural adaptation in human quadriceps muscles
J Appl Physiol 103: 1565-1575, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00578.2007 [Abstract] [Full Text] [PDF]  

Edward L. Melanson, William T. Donahoo, Gary K. Grunwald, and Robert Schwartz

Changes in 24-h substrate oxidation in older and younger men in response to exercise
J Appl Physiol 103: 1576-1582, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.01455.2006 [Abstract] [Full Text] [PDF]  

Beth A. Parker, Sandra L. Smithmyer, Justin A. Pelberg, Aaron D. Mishkin, Michael D. Herr, and David N. Proctor

Sex differences in leg vasodilation during graded knee extensor exercise in young adults
J Appl Physiol 103: 1583-1591, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00662.2007 [Abstract] [Full Text] [PDF]  

A. S. Brown, J. M. Davis, E. A. Murphy, M. D. Carmichael, J. A. Carson, A. Ghaffar, and E. P. Mayer

Susceptibility to HSV-1 infection and exercise stress in female mice: role of estrogen
J Appl Physiol 103: 1592-1597, 2007. First published September 6, 2007; doi:10.1152/japplphysiol.00677.2007 [Abstract] [Full Text] [PDF]  

Elju E. Thomas, Giuseppe De Vito, and Andrea Macaluso

Speed training with body weight unloading improves walking energy cost and maximal speed in 75- to 85-year-old healthy women
J Appl Physiol 103: 1598-1603, 2007. First published September 6, 2007; doi:10.1152/japplphysiol.00399.2007 [Abstract] [Full Text] [PDF]  

Gregory C. Henderson, Jill A. Fattor, Michael A. Horning, Nastaran Faghihnia, Mona Luke-Zeitoun, and George A. Brooks

Retention of intravenously infused [¹³C]bicarbonate is transiently increased during recovery from hard exercise
J Appl Physiol 103: 1604-1612, 2007. First published August 16, 2007; doi:10.1152/japplphysiol.00309.2007 [Abstract] [Full Text] [PDF]  

Kevin R. Rarick, Matthew A. Pikosky, Ann Grediagin, Tracey J. Smith, Ellen L. Glickman, Joseph A. Alemany, Jeffery S. Staab, Andrew J. Young, and Bradley C. Nindl

Energy flux, more so than energy balance, protein intake, or fitness level, influences insulin-like growth factor-I system responses during 7 days of increased physical activity
J Appl Physiol 103: 1613-1621, 2007. First published August 16, 2007; doi:10.1152/japplphysiol.00179.2007 [Abstract] [Full Text] [PDF]  

Lauren Howitt, Kristina Kairaitis, Jason P. Kirkness, Sarah R. Garlick, John R. Wheatley, Karen Byth, and Terence C. Amis

Oscillatory pressure wave transmission from the upper airway to the carotid artery
J Appl Physiol 103: 1622-1627, 2007. First published August 16, 2007; doi:10.1152/japplphysiol.01413.2006 [Abstract] [Full Text] [PDF]  

Linda H. Chung, Damien M. Callahan, and Jane A. Kent-Braun

Age-related resistance to skeletal muscle fatigue is preserved during ischemia
J Appl Physiol 103: 1628-1635, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00320.2007 [Abstract] [Full Text] [PDF]  

Michael W. Ramsey, Bradley J. Behnke, Rhonda D. Prisby, and Michael D. Delp

Effects of aging on adipose resistance artery vasoconstriction: possible implications for orthostatic blood pressure regulation
J Appl Physiol 103: 1636-1643, 2007. First published September 20, 2007; doi:10.1152/japplphysiol.00637.2007 [Abstract] [Full Text] [PDF]  

G. R. Adams, F. Haddad, P. W. Bodell, P. D. Tran, and K. M. Baldwin

Combined isometric, concentric, and eccentric resistance exercise prevents unloading-induced muscle atrophy in rats
J Appl Physiol 103: 1644-1654, 2007. First published September 13, 2007; doi:10.1152/japplphysiol.00669.2007 [Abstract] [Full Text] [PDF]  

Takanobu Okamoto, Mitsuhiko Masuhara, and Komei Ikuta

Combined aerobic and resistance training and vascular function: effect of aerobic exercise before and after resistance training
J Appl Physiol 103: 1655-1661, 2007. First published September 13, 2007; doi:10.1152/japplphysiol.00327.2007 [Abstract] [Full Text] [PDF]  

Arie Oliven, Majed Odeh, Louis Geitini, Ron Oliven, Uri Steinfeld, Alan R. Schwartz, and Nave Tov

Effect of coactivation of tongue protrusor and retractor muscles on pharyngeal lumen and airflow in sleep apnea patients
J Appl Physiol 103: 1662-1668, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00620.2007 [Abstract] [Full Text] [PDF]  

Makoto Takahashi, Kanji Matsukawa, Tomoko Nakamoto, Hirotsugu Tsuchimochi, Akihiro Sakaguchi, Kotaro Kawaguchi, and Kiyoshi Onari

Control of heart rate variability by cardiac parasympathetic nerve activity during voluntary static exercise in humans with tetraplegia
J Appl Physiol 103: 1669-1677, 2007. First published August 30, 2007; doi:10.1152/japplphysiol.00503.2007 [Abstract] [Full Text] [PDF]  

Brian D. Hand, Matthew C. Kostek, Robert E. Ferrell, Matthew J. Delmonico, Larry W. Douglass, Stephen M. Roth, James M. Hagberg, and Ben F. Hurley

Influence of promoter region variants of insulin-like growth factor pathway genes on the strength-training response of muscle phenotypes in older adults
J Appl Physiol 103: 1678-1687, 2007. First published August 30, 2007; doi:10.1152/japplphysiol.00420.2007 [Abstract] [Full Text] [PDF]  

Noriko I. Tanaka, Masae Miyatani, Yoshihisa Masuo, Tetsuo Fukunaga, and Hiroaki Kanehisa

Applicability of a segmental bioelectrical impedance analysis for predicting the whole body skeletal muscle volume
J Appl Physiol 103: 1688-1695, 2007. First published August 30, 2007; doi:10.1152/japplphysiol.00255.2007 [Abstract] [Full Text] [PDF]  

Jason H. T. Bates, Ana Cojocaru, and Lennart K. A. Lundblad

Bronchodilatory effect of deep inspiration on the dynamics of bronchoconstriction in mice
J Appl Physiol 103: 1696-1705, 2007. First published September 20, 2007; doi:10.1152/japplphysiol.00698.2007 [Abstract] [Full Text] [PDF]  

Keith N. Bishop, J. Ross McClung, Stephen J. Goldberg, and Mary S. Shall

Anatomic and physiological characteristics of the ferret lateral rectus muscle and abducens nucleus
J Appl Physiol 103: 1706-1714, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00580.2007 [Abstract] [Full Text] [PDF]  

Kristen L. Jablonski, Douglas R. Seals, Iratxe Eskurza, Kevin D. Monahan, and Anthony J. Donato

High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men
J Appl Physiol 103: 1715-1721, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00533.2007 [Abstract] [Full Text] [PDF]  

Nicholas G. Jendzjowsky, Corey R. Tomczak, Richard Lawrance, Dylan A. Taylor, Wayne J. Tymchak, Kenneth J. Riess, Darren E. R. Warburton, and Mark J. Haykowsky

Impaired pulmonary oxygen uptake kinetics and reduced peak aerobic power during small muscle mass exercise in heart transplant recipients
J Appl Physiol 103: 1722-1727, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00725.2007 [Abstract] [Full Text] [PDF]  

David C. Nieman, Dru A. Henson, J. Mark Davis, E. Angela Murphy, David P. Jenkins, Sarah J. Gross, Martin D. Carmichael, John C. Quindry, Charles L. Dumke, Alan C. Utter, Steven R. McAnulty, Lisa S. McAnulty, N. Travis Triplett, and Eugene P. Mayer

Quercetin's influence on exercise-induced changes in plasma cytokines and muscle and leukocyte cytokine mRNA
J Appl Physiol 103: 1728-1735, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00707.2007 [Abstract] [Full Text] [PDF]  

Wim Derave, Mahir S. Özdemir, Roger C. Harris, Andries Pottier, Harmen Reyngoudt, Katrien Koppo, John A. Wise, and Eric Achten

-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters
J Appl Physiol 103: 1736-1743, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00397.2007 [Abstract] [Full Text] [PDF]  

Emily Louis, Ulrika Raue, Yifan Yang, Bozena Jemiolo, and Scott Trappe

Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle
J Appl Physiol 103: 1744-1751, 2007. First published September 6, 2007; doi:10.1152/japplphysiol.00679.2007 [Abstract] [Full Text] [PDF]  

T. M. Altenburg, H. Degens, W. van Mechelen, A. J. Sargeant, and A. de Haan

Recruitment of single muscle fibers during submaximal cycling exercise
J Appl Physiol 103: 1752-1756, 2007. First published September 6, 2007; doi:10.1152/japplphysiol.00496.2007 [Abstract] [Full Text] [PDF]  

Bradley J. Behnke, Michael D. Delp, David C. Poole, and Timothy I. Musch

Aging potentiates the effect of congestive heart failure on muscle microvascular oxygenation
J Appl Physiol 103: 1757-1763, 2007. First published August 30, 2007; doi:10.1152/japplphysiol.00487.2007 [Abstract] [Full Text] [PDF]  

Sunmin Park, Sang Mee Hong, Ji Eun Lee, and So Ra Sung

Exercise improves glucose homeostasis that has been impaired by a high-fat diet by potentiating pancreatic -cell function and mass through IRS2 in diabetic rats
J Appl Physiol 103: 1764-1771, 2007. First published August 30, 2007; doi:10.1152/japplphysiol.00434.2007 [Abstract] [Full Text] [PDF]  

Ben-Shiang Deng, Akira Nakamura, Wei Zhang, Masashi Yanagisawa, Yasuichiro Fukuda, and Tomoyuki Kuwaki

Contribution of orexin in hypercapnic chemoreflex: evidence from genetic and pharmacological disruption and supplementation studies in mice
J Appl Physiol 103: 1772-1779, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00075.2007 [Abstract] [Full Text] [PDF]  

Mirela B. Dias, Tatiane B. Nucci, Lisandra O. Margatho, José Antunes-Rodrigues, Luciane H. Gargaglioni, and Luiz G. S. Branco

Raphe magnus nucleus is involved in ventilatory but not hypothermic response to CO₂
J Appl Physiol 103: 1780-1788, 2007. First published September 6, 2007; doi:10.1152/japplphysiol.00424.2007 [Abstract] [Full Text] [PDF]  

Samar Farha, Kewal Asosingh, Daniel Laskowski, Lauren Licina, Haruki Sekigushi, Douglas W. Losordo, Raed A. Dweik, Herbert P. Wiedemann, and Serpil C. Erzurum

Pulmonary gas transfer related to markers of angiogenesis during the menstrual cycle
J Appl Physiol 103: 1789-1795, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00614.2007 [Abstract] [Full Text] [PDF]  

H. C. Yalcin, S. F. Perry, and S. N. Ghadiali

Influence of airway diameter and cell confluence on epithelial cell injury in an in vitro model of airway reopening
J Appl Physiol 103: 1796-1807, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00164.2007 [Abstract] [Full Text] [PDF]  

Yu-Shang Lee, Ching-Yi Lin, Vincent J. Caiozzo, Richard T. Robertson, Jen Yu, and Vernon W. Lin

Repair of spinal cord transection and its effects on muscle mass and myosin heavy chain isoform phenotype
J Appl Physiol 103: 1808-1814, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00588.2007 [Abstract] [Full Text] [PDF]  

Michael J. Lyon, Linda M. Steer, and Leslie T. Malmgren

Stereological estimates indicate that aging does not alter the capillary length density in the human posterior cricoarytenoid muscle
J Appl Physiol 103: 1815-1823, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00030.2007 [Abstract] [Full Text] [PDF]  

Sherif M. ElBasiouny and Vivian K. Mushahwar

Suppressing the excitability of spinal motoneurons by extracellularly applied electrical fields: insights from computer simulations
J Appl Physiol 103: 1824-1836, 2007. First published August 16, 2007; doi:10.1152/japplphysiol.00362.2007 [Abstract] [Full Text] [PDF]  

Matthew A. Neimark, Angelos-Aristeidis Konstas, Andrew F. Laine, and John Pile-Spellman

Integration of jugular venous return and circle of Willis in a theoretical human model of selective brain cooling
J Appl Physiol 103: 1837-1847, 2007. First published August 30, 2007; doi:10.1152/japplphysiol.00542.2007 [Abstract] [Full Text] [PDF]  

Wilfred W. Lam, David W. Holdsworth, Louise Y. Du, Maria Drangova, David G. McCormack, and Giles E. Santyr

Micro-CT imaging of rat lung ventilation using continuous image acquisition during xenon gas contrast enhancement
J Appl Physiol 103: 1848-1856, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00009.2007 [Abstract] [Full Text] [PDF]  

Ioannis Stratos, Robert Rotter, Christian Eipel, Thomas Mittlmeier, and Brigitte Vollmar

Granulocyte-colony stimulating factor enhances muscle proliferation and strength following skeletal muscle injury in rats
J Appl Physiol 103: 1857-1863, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00066.2007 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY

Duygu Onat, Sanja Jelic, Ann Marie Schmidt, John Pile-Spellman, Shunichi Homma, Margherita Padeletti, Zhezhen Jin, Thierry H. Le Jemtel, Paolo C. Colombo, and Lei Feng

Vascular endothelial sampling and analysis of gene transcripts: a new quantitative approach to monitor vascular inflammation
J Appl Physiol 103: 1873-1878, 2007. First published August 23, 2007; doi:10.1152/japplphysiol.00367.2007 [Abstract] [Full Text] [PDF]  

Yifan Yang, Michael Baker, Scott Graf, Jennifer Larson, and Vincent J. Caiozzo

Hypergravity resistance exercise: the use of artificial gravity as potential countermeasure to microgravity
J Appl Physiol 103: 1879-1887, 2007. First published September 13, 2007; doi:10.1152/japplphysiol.00772.2007 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

L. V. Zingman, A. E. Alekseev, D. M. Hodgson-Zingman, and A. Terzic

ATP-sensitive potassium channels: metabolic sensing and cardioprotection
J Appl Physiol 103: 1888-1893, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00747.2007 [Abstract] [Full Text] [PDF]  

David A. Brown and Russell L. Moore

Perspectives in innate and acquired cardioprotection: cardioprotection acquired through exercise
J Appl Physiol 103: 1894-1899, 2007. First published June 7, 2007; doi:10.1152/japplphysiol.00464.2007 [Abstract] [Full Text] [PDF]  

POINT-COUNTERPOINT

Jason H. T. Bates

Point:Counterpoint: Lung impedance measurements are/are not more useful than simpler measurements of lung function in animal models of pulmonary disease
J Appl Physiol 103: 1900-1901, 2007. First published April 12, 2007; doi:10.1152/japplphysiol.00369.2007 [Full Text] [PDF]  

Wayne Mitzner

Counterpoint: Lung Impedance Measurements are not More Useful than Simpler Measurements of Lung Function in Animal Models of Pulmonary Disease
J Appl Physiol 103: 1901-1903, 2007; doi:10.1152/japplphysiol.00369.2007a [Full Text] [PDF]  

Rebuttal from Dr. Bates
J Appl Physiol 103: 1903-1904, 2007; doi:10.1152/japplphysiol.00369.2007b [Full Text] [PDF]  

Rebuttal from Dr. Mitzner
J Appl Physiol 103: 1904-1904, 2007; doi:10.1152/japplphysiol.00369.2007c [Full Text] [PDF]  

POINT-COUNTERPOINT COMMENTS

J. Craig Cohen, Joesph Hudak, Jeffrey J. Fredberg, Zoltán Hantos, Darryl C. Zeldin, Jeffrey W. Card, Michelle A. Carey, James W. Voltz, Bela Suki, Kenneth R. Lutchen, David W. Kaczka, Brett A. Simon, Lennart K. A. Lundblad, and Brett A. Simon

Lung impedance measurements are/are not more useful than simpler measurements of lung function in animal models of pulmonary disease
J Appl Physiol 103: 1905-1908, 2007; doi:10.1152/japplphysiol.00759.2007 [Full Text] [PDF]  

LETTERS TO THE EDITOR

Jason H. T. Bates

Last Word on Point:Counterpoint: Lung impedance measurements are/are not more useful than simpler measurements of lung function in animal models of pulmonary disease
J Appl Physiol 103: 1909-1909, 2007; doi:10.1152/japplphysiol.00769.2007 [Full Text] [PDF]  

Wayne Mitzner

Last Word on Point:Counterpoint: Lung impedance measurements are/are not more useful than simpler measurements of lung function in animal models of pulmonary disease
J Appl Physiol 103: 1910-1910, 2007; doi:10.1152/japplphysiol.00748.2007 [Full Text] [PDF]  

David Bishop

Is supramaximal work capacity negatively correlated with the rate of decrease in muscle pH?
J Appl Physiol 103: 1911-1911, 2007; doi:10.1152/japplphysiol.00784.2007 [Full Text] [PDF]  

Laurent Messonnier and Christian Denis

Reply to Dr. Bishop
J Appl Physiol 103: 1912-1913, 2007; doi:10.1152/japplphysiol.00943.2007 [Full Text] [PDF]  

Katja M. Heinemeier

Using ribosomal RNA as a reference in mRNA quantification
J Appl Physiol 103: 1914-1914, 2007; doi:10.1152/japplphysiol.00862.2007 [Full Text] [PDF]  

Marcas M. Bamman

Reply to Dr. Heinemeier
J Appl Physiol 103: 1915-1915, 2007; doi:10.1152/japplphysiol.00946.2007 [Full Text] [PDF]  

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