INVITED EDITORIAL

Paul W. Franks

Muscling in on the genetics of quantitative disease traits
J Appl Physiol 103: 1111-1112, 2007. First published August 16, 2007; doi:10.1152/japplphysiol.00827.2007 [Full Text] [PDF]  

INVITED REVIEWS

Stephan F. E. Praet and Luc J. C. van Loon

Optimizing the therapeutic benefits of exercise in Type 2 diabetes
J Appl Physiol 103: 1113-1120, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.00566.2007 [Abstract] [Full Text] [PDF]  

ARTICLES

Steven J. Prior, Stephen M. Roth, Xiaojing Wang, Candace Kammerer, Iva Miljkovic-Gacic, Clareann H. Bunker, Victor W. Wheeler, Alan L. Patrick, and Joseph M. Zmuda

Genetic and environmental influences on skeletal muscle phenotypes as a function of age and sex in large, multigenerational families of African heritage
J Appl Physiol 103: 1121-1127, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.00120.2007 [Abstract] [Full Text] [PDF]  

Shizue Masuki, John H. Eisenach, William G. Schrage, Christopher P. Johnson, Niki M. Dietz, Brad W. Wilkins, Paola Sandroni, Phillip A. Low, and Michael J. Joyner

Reduced stroke volume during exercise in postural tachycardia syndrome
J Appl Physiol 103: 1128-1135, 2007. First published July 12, 2007; doi:10.1152/japplphysiol.00175.2007 [Abstract] [Full Text] [PDF]  

Shizue Masuki, John H. Eisenach, William G. Schrage, Niki M. Dietz, Christopher P. Johnson, Brad W. Wilkins, Ross A. Dierkhising, Paola Sandroni, Phillip A. Low, and Michael J. Joyner

Arterial baroreflex control of heart rate during exercise in postural tachycardia syndrome
J Appl Physiol 103: 1136-1142, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00176.2007 [Abstract] [Full Text] [PDF]  

Alberto Porta, Tomaso Gnecchi-Ruscone, Eleonora Tobaldini, Stefano Guzzetti, Raffaello Furlan, and Nicola Montano

Progressive decrease of heart period variability entropy-based complexity during graded head-up tilt
J Appl Physiol 103: 1143-1149, 2007. First published June 14, 2007; doi:10.1152/japplphysiol.00293.2007 [Abstract] [Full Text] [PDF]  

Vincent J. Caiozzo, Heather Richmond, Serge Kaska, and Dahlia Valeroso

The mechanical behavior of activated skeletal muscle during stretch: effects of muscle unloading and MyHC isoform shifts
J Appl Physiol 103: 1150-1160, 2007. First published June 14, 2007; doi:10.1152/japplphysiol.00469.2006 [Abstract] [Full Text] [PDF]  

Vitalie Faoro, Sandrine Huez, Sébastien Giltaire, Adriana Pavelescu, Aurélie van Osta, Jean-Jacques Moraine, Hervé Guenard, Jean-Benoît Martinot, and Robert Naeije

Effects of acetazolamide on aerobic exercise capacity and pulmonary hemodynamics at high altitudes
J Appl Physiol 103: 1161-1165, 2007. First published July 5, 2007; doi:10.1152/japplphysiol.00180.2007 [Abstract] [Full Text] [PDF]  

Carmen G. C. Vinagre, Elisabeth S. Ficker, Claudia Finazzo, Maria J. N. Alves, Katia de Angelis, Maria Claudia Irigoyen, Carlos E. Negrão, and Raul C. Maranhão

Enhanced removal from the plasma of LDL-like nanoemulsion cholesteryl ester in trained men compared with sedentary healthy men
J Appl Physiol 103: 1166-1171, 2007. First published July 12, 2007; doi:10.1152/japplphysiol.01176.2006 [Abstract] [Full Text] [PDF]  

Christopher R. Woodman, Daniel W. Trott, and M. Harold Laughlin

Short-term increases in intraluminal pressure reverse age-related decrements in endothelium-dependent dilation in soleus muscle feed arteries
J Appl Physiol 103: 1172-1179, 2007. First published July 12, 2007; doi:10.1152/japplphysiol.00416.2007 [Abstract] [Full Text] [PDF]  

Charles Duvareille, Mylène Lafrance, Nathalie Samson, Marie St-Hilaire, Patrick Pladys, Philippe Micheau, Véronique Bournival, Carole Langlois, and Jean-Paul Praud

Effects of hypoxia and hypercapnia on nonnutritive swallowing in newborn lambs
J Appl Physiol 103: 1180-1188, 2007. First published July 12, 2007; doi:10.1152/japplphysiol.00318.2007 [Abstract] [Full Text] [PDF]  

Alison S. Williams, Sum-Yee Leung, Puneeta Nath, Nadia M. Khorasani, Pankaj Bhavsar, Razao Issa, Jane A. Mitchell, Ian M. Adcock, and Kian Fan Chung

Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia
J Appl Physiol 103: 1189-1195, 2007. First published July 12, 2007; doi:10.1152/japplphysiol.00172.2007 [Abstract] [Full Text] [PDF]  

Paulette M. Yamada, Fabiano T. Amorim, Pope Moseley, Robert Robergs, and Suzanne M. Schneider

Effect of heat acclimation on heat shock protein 72 and interleukin-10 in humans
J Appl Physiol 103: 1196-1204, 2007. First published July 5, 2007; doi:10.1152/japplphysiol.00242.2007 [Abstract] [Full Text] [PDF]  

Jalal M. Abu-Shaweesh

Activation of central adenosine A_2A receptors enhances superior laryngeal nerve stimulation-induced apnea in piglets via a GABAergic pathway
J Appl Physiol 103: 1205-1211, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.01420.2006 [Abstract] [Full Text] [PDF]  

T. A. Duhamel, R. D. Stewart, A. R. Tupling, J. Ouyang, and H. J. Green

Muscle sarcoplasmic reticulum calcium regulation in humans during consecutive days of exercise and recovery
J Appl Physiol 103: 1212-1220, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.00437.2007 [Abstract] [Full Text] [PDF]  

Takeshi Ogawa, Keiji Hayashi, Masashi Ichinose, and Takeshi Nishiyasu

Relationship between resting ventilatory chemosensitivity and maximal oxygen uptake in moderate hypobaric hypoxia
J Appl Physiol 103: 1221-1226, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.00153.2007 [Abstract] [Full Text] [PDF]  

H. B. Nielsen, M. A. Febbraio, P. Ott, P. Krustrup, and N. H. Secher

Hepatic lactate uptake versus leg lactate output during exercise in humans
J Appl Physiol 103: 1227-1233, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.00027.2007 [Abstract] [Full Text] [PDF]  

James E. Fewell, Chunfen Zhang, and Anne M. Gillis

Influence of adenosine A₁-receptor blockade and vagotomy on the gasping and heart rate response to hypoxia in rats during early postnatal maturation
J Appl Physiol 103: 1234-1241, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.01421.2006 [Abstract] [Full Text] [PDF]  

Scott Trappe, Andrew Creer, Dustin Slivka, Kiril Minchev, and Todd Trappe

Single muscle fiber function with concurrent exercise or nutrition countermeasures during 60 days of bed rest in women
J Appl Physiol 103: 1242-1250, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00560.2007 [Abstract] [Full Text] [PDF]  

Martin Whitham, Stewart J. Laing, Anna Jackson, Norbert Maassen, and Neil P. Walsh

Effect of exercise with and without a thermal clamp on the plasma heat shock protein 72 response
J Appl Physiol 103: 1251-1256, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00484.2007 [Abstract] [Full Text] [PDF]  

Thad E. Wilson, Charity L. Sauder, Matthew L. Kearney, Nathan T. Kuipers, Urs A. Leuenberger, Kevin D. Monahan, and Chester A. Ray

Skin-surface cooling elicits peripheral and visceral vasoconstriction in humans
J Appl Physiol 103: 1257-1262, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00401.2007 [Abstract] [Full Text] [PDF]  

Motoo Yamauchi, Jesse Dostal, and Kingman P. Strohl

Acetazolamide protects against posthypoxic unstable breathing in the C57BL/6J mouse
J Appl Physiol 103: 1263-1268, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.01287.2006 [Abstract] [Full Text] [PDF]  

J. Prieto-Lloret, D. F. Donnelly, A. J. Rico, R. Moratalla, C. González, and R. J. Rigual

Hypoxia transduction by carotid body chemoreceptors in mice lacking dopamine D₂ receptors
J Appl Physiol 103: 1269-1275, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00391.2007 [Abstract] [Full Text] [PDF]  

M. Hoffrén, M. Ishikawa, and P. V. Komi

Age-related neuromuscular function during drop jumps
J Appl Physiol 103: 1276-1283, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00430.2007 [Abstract] [Full Text] [PDF]  

Jian Cui, Sylvain Durand, and Craig G. Crandall

Baroreflex control of muscle sympathetic nerve activity during skin surface cooling
J Appl Physiol 103: 1284-1289, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00115.2007 [Abstract] [Full Text] [PDF]  

Min-Hui Cui, Jong-Hee Hwang, Vlad Tomuta, Zhengchao Dong, and Daniel T. Stein

Cross contamination of intramyocellular lipid signals through loss of bulk magnetic susceptibility effect differences in human muscle using ¹H-MRSI at 4 T
J Appl Physiol 103: 1290-1298, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.01088.2006 [Abstract] [Full Text] [PDF]  

Michael I. Lewis, Mario Fournier, Thomas W. Storer, Shalender Bhasin, Janos Porszasz, Song-Guang Ren, Xiaoyu Da, and Richard Casaburi

Skeletal muscle adaptations to testosterone and resistance training in men with COPD
J Appl Physiol 103: 1299-1310, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00150.2007 [Abstract] [Full Text] [PDF]  

Guido Wassink, Laura Bennet, Lindsea C. Booth, Ellen C. Jensen, Bert Wibbens, Justin M. Dean, and Alistair Jan Gunn

The ontogeny of hemodynamic responses to prolonged umbilical cord occlusion in fetal sheep
J Appl Physiol 103: 1311-1317, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.00396.2007 [Abstract] [Full Text] [PDF]  

Stéphane Baudry and Jacques Duchateau

Postactivation potentiation in a human muscle: effect on the load-velocity relation of tetanic and voluntary shortening contractions
J Appl Physiol 103: 1318-1325, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00403.2007 [Abstract] [Full Text] [PDF]  

Koichi Kurihara, Azusa Kikukawa, Asao Kobayashi, and Toshio Nakadate

Frontal cortical oxygenation changes during gravity-induced loss of consciousness in humans: a near-infrared spatially resolved spectroscopic study
J Appl Physiol 103: 1326-1331, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.01191.2006 [Abstract] [Full Text] [PDF]  

Mohammad Zaregarizi, Ben Edwards, Keith George, Yvonne Harrison, Helen Jones, and Greg Atkinson

Acute changes in cardiovascular function during the onset period of daytime sleep: comparison to lying awake and standing
J Appl Physiol 103: 1332-1338, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00474.2007 [Abstract] [Full Text] [PDF]  

John Q. Zhang, Lisa L. Ji, Donovan L. Fogt, and Vicki S. Fretwell

Effect of exercise duration on postprandial hypertriglyceridemia in men with metabolic syndrome
J Appl Physiol 103: 1339-1345, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00181.2007 [Abstract] [Full Text] [PDF]  

François Haman, Chris G. Scott, and Glen P. Kenny

Fueling shivering thermogenesis during passive hypothermic recovery
J Appl Physiol 103: 1346-1351, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00931.2006 [Abstract] [Full Text] [PDF]  

Kazuto Masamoto, Jeff Kershaw, Masakatsu Ureshi, Naosada Takizawa, Hirosuke Kobayashi, Kazuo Tanishita, and Iwao Kanno

Apparent diffusion time of oxygen from blood to tissue in rat cerebral cortex: implication for tissue oxygen dynamics during brain functions
J Appl Physiol 103: 1352-1358, 2007. First published July 12, 2007; doi:10.1152/japplphysiol.01433.2006 [Abstract] [Full Text] [PDF]  

Gordon G. Power, Shannon L. Bragg, Bryan T. Oshiro, Andre Dejam, Christian J. Hunter, and Arlin B. Blood

A novel method of measuring reduction of nitrite-induced methemoglobin applied to fetal and adult blood of humans and sheep
J Appl Physiol 103: 1359-1365, 2007. First published July 5, 2007; doi:10.1152/japplphysiol.00443.2007 [Abstract] [Full Text] [PDF]  

Nicola Lai, Gerald M. Saidel, Bruno Grassi, L. Bruce Gladden, and Marco E. Cabrera

Model of oxygen transport and metabolism predicts effect of hyperoxia on canine muscle oxygen uptake dynamics
J Appl Physiol 103: 1366-1378, 2007. First published June 28, 2007; doi:10.1152/japplphysiol.00489.2007 [Abstract] [Full Text] [PDF]  

Yugo Tagaito, Shiroh Isono, John E. Remmers, Atsuko Tanaka, and Takashi Nishino

Lung volume and collapsibility of the passive pharynx in patients with sleep-disordered breathing
J Appl Physiol 103: 1379-1385, 2007. First published June 28, 2007; doi:10.1152/japplphysiol.00026.2007 [Abstract] [Full Text] [PDF]  

Norberto C. Gonzalez, Julie Allen, V. Gustavo Blanco, Eric J. Schmidt, Nico van Rooijen, and John G. Wood

Alveolar macrophages are necessary for the systemic inflammation of acute alveolar hypoxia
J Appl Physiol 103: 1386-1394, 2007. First published July 26, 2007; doi:10.1152/japplphysiol.00312.2007 [Abstract] [Full Text] [PDF]  

Riikka Kivelä, Heikki Kyröläinen, Harri Selänne, Paavo V. Komi, Heikki Kainulainen, and Veikko Vihko

A single bout of exercise with high mechanical loading induces the expression of Cyr61/CCN1 and CTGF/CCN2 in human skeletal muscle
J Appl Physiol 103: 1395-1401, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00531.2007 [Abstract] [Full Text] [PDF]  

Savio W. Wong, Derek S. Kimmerly, Nicholas Massé, Ravi S. Menon, David F. Cechetto, and J. Kevin Shoemaker

Sex differences in forebrain and cardiovagal responses at the onset of isometric handgrip exercise: a retrospective fMRI study
J Appl Physiol 103: 1402-1411, 2007. First published July 5, 2007; doi:10.1152/japplphysiol.00171.2007 [Abstract] [Full Text] [PDF]  

Marco Testa, Bianca Rocca, Lucia Spath, Franco O. Ranelletti, Giovanna Petrucci, Giovanni Ciabattoni, Fabio Naro, Stefano Schiaffino, Massimo Volpe, and Carlo Reggiani

Expression and activity of cyclooxygenase isoforms in skeletal muscles and myocardium of humans and rodents
J Appl Physiol 103: 1412-1418, 2007. First published August 2, 2007; doi:10.1152/japplphysiol.00288.2007 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY

Megan P. Rothney, Megan Neumann, Ashley Béziat, and Kong Y. Chen

An artificial neural network model of energy expenditure using nonintegrated acceleration signals
J Appl Physiol 103: 1419-1427, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00429.2007 [Abstract] [Full Text] [PDF]  

Alexander Stahn, Elmarie Terblanche, and Günther Strobel

Modeling upper and lower limb muscle volume by bioelectrical impedance analysis
J Appl Physiol 103: 1428-1435, 2007. First published July 12, 2007; doi:10.1152/japplphysiol.01163.2006 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

Andre Terzic, Russell L. Moore, and Scott A. Waldman

Acquired and innate cardioprotection
J Appl Physiol 103: 1436-1437, 2007. First published August 9, 2007; doi:10.1152/japplphysiol.00834.2007 [Full Text] [PDF]  

Atta Behfar and Andre Terzic

Cardioprotective repair through stem cell-based cardiopoiesis
J Appl Physiol 103: 1438-1440, 2007. First published July 19, 2007; doi:10.1152/japplphysiol.00713.2007 [Abstract] [Full Text] [PDF]  

Jakob Vinten-Johansen, Zhi-Qing Zhao, Rong Jiang, Amanda J. Zatta, and Geoffrey P. Dobson

Preconditioning and postconditioning: innate cardioprotection from ischemia-reperfusion injury
J Appl Physiol 103: 1441-1448, 2007. First published July 5, 2007; doi:10.1152/japplphysiol.00642.2007 [Abstract] [Full Text] [PDF]  

POINT-COUNTERPOINT

Marlene Rabinovitch, Naomi Chesler, and Robert C. Molthen

Point:Counterpoint: Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature
J Appl Physiol 103: 1449-1451, 2007. First published March 15, 2007; doi:10.1152/japplphysiol.00274.2007 [Full Text] [PDF]  

P. McLoughlin and I. McMurtry

Counterpoint: Chronic Hypoxia-induced Pulmonary Hypertension does not Lead to Loss of Pulmonary Vasculature
J Appl Physiol 103: 1451-1453, 2007; doi:10.1152/japplphysiol.00274.2007a [Full Text] [PDF]  

Rebuttal from Drs. Rabinovitch, Chesler, and Moulthen
J Appl Physiol 103: 1453-1453, 2007; doi:10.1152/japplphysiol.00274.2007b [Full Text] [PDF] [Correction]  

Rebuttal from Drs. Mcloughlin and Mcmurtry
J Appl Physiol 103: 1453-1454, 2007; doi:10.1152/japplphysiol.00274.2007c [Full Text] [PDF]  

POINT-COUNTERPOINT COMMENTS

John T. Berg

Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature
J Appl Physiol 103: 1455-1455, 2007; doi:10.1152/japplphysiol.00739.2007 [Full Text] [PDF]  

LETTERS TO THE EDITOR

Paul McLoughlin and Ivan McMurtry

Last Word on Point:Counterpoint "Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature"
J Appl Physiol 103: 1456-1456, 2007; doi:10.1152/japplphysiol.00716.2007 [Full Text] [PDF]  

Peter Macklem

Commentary on "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1459-1459, 2007; doi:10.1152/japplphysiol.00646.2007 [Full Text] [PDF]  

Riccardo Pellegrino and Vito Brusasco

Commentary on "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1460-1460, 2007; doi:10.1152/japplphysiol.00684.2007 [Full Text] [PDF]  

Howard Mitchell, Peter Noble, and Peter McFawn

Commentary on "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1461-1461, 2007; doi:10.1152/japplphysiol.00665.2007 [Full Text] [PDF]  

Newman Stephens

Commentary on "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1462-1462, 2007; doi:10.1152/japplphysiol.00629.2007 [Full Text] [PDF]  

Hans Christian Haverkamp and Lennart Karl Alf Lundblad

Commentary on "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1463-1463, 2007; doi:10.1152/japplphysiol.00703.2007 [Full Text] [PDF]  

Ronald Sorkness

Commentary on "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1464-1464, 2007; doi:10.1152/japplphysiol.00702.2007 [Full Text] [PDF]  

Bruce Thompson, Greg King, and Richard Harding

Commentary on "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1465-1465, 2007; doi:10.1152/japplphysiol.00696.2007 [Full Text] [PDF]  

Solbert Permutt

Last Word on Viewpoint "The role of the large airways on smooth muscle contraction in asthma"
J Appl Physiol 103: 1466-1466, 2007; doi:10.1152/japplphysiol.00822.2007 [Full Text] [PDF]  

VIEWPOINT

Solbert Permutt

The role of the large airways on smooth muscle contraction in asthma
J Appl Physiol 103: 1457-1458, 2007. First published May 31, 2007; doi:10.1152/japplphysiol.00568.2007 [Full Text] [PDF]  

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