INVITED EDITORIAL

Bettina Mittendorfer and Michael J. Rennie

Swings and roundabouts for muscle gain and loss: differences between sexes?
J Appl Physiol 100: 375-376, 2006; doi:10.1152/japplphysiol.01289.2005 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY

Stacy L. Sommer, Theresa J. Berndt, Elena Frank, Jeetendra B. Patel, Margaret M. Redfield, Xiangyang Dong, Matthew D. Griffin, Joseph P. Grande, Jan M. A. van Deursen, Gary C. Sieck, Juan C. Romero, and Rajiv Kumar

Elevated blood pressure and cardiac hypertrophy after ablation of the gly96/IEX-1 gene
J Appl Physiol 100: 707-716, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00306.2005 [Abstract] [Full Text] [PDF]  

ARTICLES

Carley R. Benton, Xiao-Xia Han, Maria Febbraio, Terry E. Graham, and Arend Bonen

Inverse relationship between PGC-1 protein expression and triacylglycerol accumulation in rodent skeletal muscle
J Appl Physiol 100: 377-383, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.00781.2005 [Abstract] [Full Text] [PDF]  

Nikolai Aljuri, Jose G. Venegas, and Lutz Freitag

Viscoelasticity of the trachea and its effects on flow limitation
J Appl Physiol 100: 384-389, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00689.2005 [Abstract] [Full Text] [PDF]  

Raymond C. Browning, Emily A. Baker, Jessica A. Herron, and Rodger Kram

Effects of obesity and sex on the energetic cost and preferred speed of walking
J Appl Physiol 100: 390-398, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00767.2005 [Abstract] [Full Text] [PDF]  

Ming C. Gong, Sandrine Arbogast, Zhenheng Guo, Jeremy Mathenia, Wen Su, and Michael B. Reid

Calcium-independent phospholipase A₂ modulates cytosolic oxidant activity and contractile function in murine skeletal muscle cells
J Appl Physiol 100: 399-405, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00873.2005 [Abstract] [Full Text] [PDF]  

Chad R. Hancock, Edwin Janssen, and Ronald L. Terjung

Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient mice
J Appl Physiol 100: 406-413, 2006. First published September 29, 2005; doi:10.1152/japplphysiol.00885.2005 [Abstract] [Full Text] [PDF]  

Keiji Hayashi, Yasushi Honda, Takeshi Ogawa, Narihiko Kondo, and Takeshi Nishiyasu

Relationship between ventilatory response and body temperature during prolonged submaximal exercise
J Appl Physiol 100: 414-420, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00541.2005 [Abstract] [Full Text] [PDF]  

Zhaohui Gao, Oze Henig, Valerie Kehoe, Lawrence I. Sinoway, and Jianhua Li

Vanilloid type 1 receptor and the acid-sensing ion channel mediate acid phosphate activation of muscle afferent nerves in rats
J Appl Physiol 100: 421-426, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00659.2005 [Abstract] [Full Text] [PDF]  

Sara Fagnété, Connes Philippe, Hue Olivier, Montout-Hedreville Mona, Etienne-Julan Maryse, and Hardy-Dessources Marie-Dominique

Faster lactate transport across red blood cell membrane in sickle cell trait carriers
J Appl Physiol 100: 427-432, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00771.2005 [Abstract] [Full Text] [PDF]  

F. Haddad, G. R. Adams, P. W. Bodell, and K. M. Baldwin

Isometric resistance exercise fails to counteract skeletal muscle atrophy processes during the initial stages of unloading
J Appl Physiol 100: 433-441, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.01203.2005 [Abstract] [Full Text] [PDF]  

Stavros A. Kavouras, Lawrence E. Armstrong, Carl M. Maresh, Douglas J. Casa, Jorge A. Herrera-Soto, Timothy P. Scheett, James Stoppani, Gary W. Mack, and William J. Kraemer

Rehydration with glycerol: endocrine, cardiovascular, and thermoregulatory responses during exercise in the heat
J Appl Physiol 100: 442-450, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00187.2005 [Abstract] [Full Text] [PDF]  

Kimberly A. Huey

Regulation of HSP25 expression and phosphorylation in functionally overloaded rat plantaris and soleus muscles
J Appl Physiol 100: 451-456, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.01022.2005 [Abstract] [Full Text] [PDF]  

T. V. Kondratiev, E. S. P. Myhre, Ø. Simonsen, T.-B. Nymark, and T. Tveita

Cardiovascular effects of epinephrine during rewarming from hypothermia in an intact animal model
J Appl Physiol 100: 457-464, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00356.2005 [Abstract] [Full Text] [PDF]  

Jefferson C. Frisbee

Impaired hemorrhage tolerance in the obese Zucker rat model of metabolic syndrome
J Appl Physiol 100: 465-473, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.01062.2005 [Abstract] [Full Text] [PDF]  

Paul McDonough, D. Merrill Dane, Connie C. W. Hsia, Cuneyt Yilmaz, and Robert L. Johnson, Jr.

Long-term enhancement of pulmonary gas exchange after high-altitude residence during maturation
J Appl Physiol 100: 474-481, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.01069.2005 [Abstract] [Full Text] [PDF]  

Xuewen Chen, Dov Jaron, Kenneth A. Barbee, and Donald G. Buerk

The influence of radial RBC distribution, blood velocity profiles, and glycocalyx on coupled NO/O₂ transport
J Appl Physiol 100: 482-492, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00633.2005 [Abstract] [Full Text] [PDF]  

Maarten F. Bobbert, Wendy W. de Graaf, Jan N. Jonk, and L. J. Richard Casius

Explanation of the bilateral deficit in human vertical squat jumping
J Appl Physiol 100: 493-499, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00637.2005 [Abstract] [Full Text] [PDF]  

Jason H. T. Bates, Scott S. Wagers, Ryan J. Norton, Lisa M. Rinaldi, and Charles G. Irvin

Exaggerated airway narrowing in mice treated with intratracheal cationic protein
J Appl Physiol 100: 500-506, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.01013.2005 [Abstract] [Full Text] [PDF]  

Tuomo Nieminen, Terho Lehtimäki, Jarno Laiho, Riikka Rontu, Kari Niemelä, Tiit Kööbi, Rami Lehtinen, Jari Viik, Väinö Turjanmaa, and Mika Kähönen

Effects of polymorphisms in ₁-adrenoceptor and -subunit of G protein on heart rate and blood pressure during exercise test. The Finnish Cardiovascular Study
J Appl Physiol 100: 507-511, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00899.2005 [Abstract] [Full Text] [PDF]  

Costantino Balestra, Peter Germonpré, Jacques R. Poortmans, and Alessandro Marroni

Serum erythropoietin levels in healthy humans after a short period of normobaric and hyperbaric oxygen breathing: the "normobaric oxygen paradox"
J Appl Physiol 100: 512-518, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00964.2005 [Abstract] [Full Text] [PDF]  

Adam J. Chicco, David S. Hydock, Carole M. Schneider, and Reid Hayward

Low-intensity exercise training during doxorubicin treatment protects against cardiotoxicity
J Appl Physiol 100: 519-527, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00148.2005 [Abstract] [Full Text] [PDF]  

Charles S. Chung, David M. Ajo, and Sándor J. Kovács

Isovolumic pressure-to-early rapid filling decay rate relation: model-based derivation and validation via simultaneous catheterization echocardiography
J Appl Physiol 100: 528-534, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.00617.2005 [Abstract] [Full Text] [PDF]  

Brett J. Wong, Sarah J. Williams, and Christopher T. Minson

Minimal role for H₁ and H₂ histamine receptors in cutaneous thermal hyperemia to local heating in humans
J Appl Physiol 100: 535-540, 2006. First published September 29, 2005; doi:10.1152/japplphysiol.00902.2005 [Abstract] [Full Text] [PDF]  

Patricia O. Reger, Mary F. Barbe, Mamta Amin, Brian F. Renna, Leigh Ann Hewston, Scott M. MacDonnell, Steven R. Houser, and Joseph R. Libonati

Myocardial hypoperfusion/reperfusion tolerance with exercise training in hypertension
J Appl Physiol 100: 541-547, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.00350.2005 [Abstract] [Full Text] [PDF]  

Amy L. Moran, Gordon L. Warren, and Dawn A. Lowe

Removal of ovarian hormones from mature mice detrimentally affects muscle contractile function and myosin structural distribution
J Appl Physiol 100: 548-559, 2006. First published October 27, 2005; doi:10.1152/japplphysiol.01029.2005 [Abstract] [Full Text] [PDF]  

E. Barreiro, J. B. Gáldiz, M. Mariñán, F. J. Alvarez, S. N. A. Hussain, J. Gea on behalf of the ENIGMA in COPD project

Respiratory loading intensity and diaphragm oxidative stress: N-acetyl-cysteine effects
J Appl Physiol 100: 555-563, 2006. First published September 29, 2005; doi:10.1152/japplphysiol.00780.2005 [Abstract] [Full Text] [PDF]  

Yiu-Fai Chen, Ji-An Feng, Peng Li, Dongqi Xing, Yun Zhang, Rosa Serra, Namasivayam Ambalavanan, Erum Majid-Hassan, and Suzanne Oparil

Dominant negative mutation of the TGF- receptor blocks hypoxia-induced pulmonary vascular remodeling
J Appl Physiol 100: 564-571, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.00595.2005 [Abstract] [Full Text] [PDF]  

Noriko Ishiguro, Hiroaki Kanehisa, Masae Miyatani, Yoshihisa Masuo, and Tetsuo Fukunaga

Applicability of segmental bioelectrical impedance analysis for predicting trunk skeletal muscle volume
J Appl Physiol 100: 572-578, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00094.2005 [Abstract] [Full Text] [PDF]  

Koji Hashimoto, Takashi Ono, Ei-ichi Honda, Keiko Maeda, Hideo Shinagawa, Satoru Tsuiki, Shigetoshi Hiyama, Tohru Kurabayashi, and Kimie Ohyama

Effects of mandibular advancement on brain activation during inspiratory loading in healthy subjects: a functional magnetic resonance imaging study
J Appl Physiol 100: 579-586, 2006. First published September 29, 2005; doi:10.1152/japplphysiol.00169.2005 [Abstract] [Full Text] [PDF]  

Elizabeth M. Wagner, Irina Petrache, Brian Schofield, and Wayne Mitzner

Pulmonary ischemia induces lung remodeling and angiogenesis
J Appl Physiol 100: 587-593, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00029.2005 [Abstract] [Full Text] [PDF]  

Richard Sindelar, Anders Jonzon, Andreas Schulze, and Gunnar Sedin

Surfactant replacement partially restores the activity of pulmonary stretch receptors in surfactant-depleted cats
J Appl Physiol 100: 594-601, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00389.2005 [Abstract] [Full Text] [PDF]  

Colleen A. McMullen and Francisco H. Andrade

Contractile dysfunction and altered metabolic profile of the aging rat thyroarytenoid muscle
J Appl Physiol 100: 602-608, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.01066.2005 [Abstract] [Full Text] [PDF]  

Martin Torriani, Bijoy J. Thomas, Robert B. Barlow, Jamie Librizzi, Sara Dolan, and Steven Grinspoon

Increased intramyocellular lipid accumulation in HIV-infected women with fat redistribution
J Appl Physiol 100: 609-614, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.00797.2005 [Abstract] [Full Text] [PDF]  

Jangwoen Lee, Naglaa El-Abaddi, Andrew Duke, Albert E. Cerussi, Matthew Brenner, and Bruce J. Tromberg

Noninvasive in vivo monitoring of methemoglobin formation and reduction with broadband diffuse optical spectroscopy
J Appl Physiol 100: 615-622, 2006. First published October 13, 2005; doi:10.1152/japplphysiol.00424.2004 [Abstract] [Full Text] [PDF]  

Hye-Won Shin, Peter Condorelli, and Steven C. George

Examining axial diffusion of nitric oxide in the lungs using heliox and breath hold
J Appl Physiol 100: 623-630, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00008.2005 [Abstract] [Full Text] [PDF]  

Qin Fang, Hong Sun, Denise M. Arrick, and William G. Mayhan

Inhibition of NADPH oxidase improves impaired reactivity of pial arterioles during chronic exposure to nicotine
J Appl Physiol 100: 631-636, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00975.2005 [Abstract] [Full Text] [PDF]  

Diane E. Wick, Shelly K. Roberts, Ananda Basu, Paola Sandroni, Robert D. Fealey, David Sletten, and Nisha Charkoudian

Delayed threshold for active cutaneous vasodilation in patients with Type 2 diabetes mellitus
J Appl Physiol 100: 637-641, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00943.2005 [Abstract] [Full Text] [PDF]  

Xing-Hai Yao, Li Chen, and B. L. Grégoire Nyomba

Adult rats prenatally exposed to ethanol have increased gluconeogenesis and impaired insulin response of hepatic gluconeogenic genes
J Appl Physiol 100: 642-648, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.01115.2005 [Abstract] [Full Text] [PDF]  

Joseph C. Anderson and Michael P. Hlastala

The kinetics of transdermal ethanol exchange
J Appl Physiol 100: 649-655, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00927.2005 [Abstract] [Full Text] [PDF]  

Erik P. Rader and John A. Faulkner

Recovery from contraction-induced injury is impaired in weight-bearing muscles of old male mice
J Appl Physiol 100: 656-661, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00663.2005 [Abstract] [Full Text] [PDF]  

S. Logsdon, A. F. M. Johnstone, K. Viele, and R. L. Cooper

Regulation of synaptic vesicles pools within motor nerve terminals during short-term facilitation and neuromodulation
J Appl Physiol 100: 662-671, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00580.2005 [Abstract] [Full Text] [PDF]  

Joanne L. Wright, Hsin Tai, and Andrew Churg

Vasoactive mediators and pulmonary hypertension after cigarette smoke exposure in the guinea pig
J Appl Physiol 100: 672-678, 2006. First published October 6, 2005; doi:10.1152/japplphysiol.00274.2005 [Abstract] [Full Text] [PDF]  

Qinyun Ruan, Liyun Rao, Katherine J. Middleton, Dirar S. Khoury, and Sherif F. Nagueh

Assessment of left ventricular diastolic function by early diastolic mitral annulus peak acceleration rate: experimental studies and clinical application
J Appl Physiol 100: 679-684, 2006. First published September 29, 2005; doi:10.1152/japplphysiol.00671.2005 [Abstract] [Full Text] [PDF]  

J. O. Hunderi, C. R. Thompson, and O. A. Smiseth

Deceleration time of systolic pulmonary venous flow: a new clinical marker of left atrial pressure and compliance
J Appl Physiol 100: 685-689, 2006. First published October 20, 2005; doi:10.1152/japplphysiol.00705.2005 [Abstract] [Full Text] [PDF]  

T. Lehmann, H. Mairbäurl, B. Pleisch, M. Maggiorini, P. Bärtsch, and W. H. Reinhart

Platelet count and function at high altitude and in high-altitude pulmonary edema
J Appl Physiol 100: 690-694, 2006; doi:10.1152/japplphysiol.00991.2005 [Abstract] [Full Text] [PDF]  

Craig D. Takahashi, Dan Nemet, Christie M. Rose-Gottron, Jennifer K. Larson, Dan M. Cooper, and David J. Reinkensmeyer

Effect of muscle fatigue on internal model formation and retention during reaching with the arm
J Appl Physiol 100: 695-706, 2006. First published October 27, 2005; doi:10.1152/japplphysiol.00140.2005 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY

F. Zhu, M. K. Kuhlmann, G. A. Kaysen, S. Sarkar, C. Kaitwatcharachai, R. Khilnani, L. Stevens, E. F. Leonard, J. Wang, S. Heymsfield, and N. W. Levin

Segment-specific resistivity improves body fluid volume estimates from bioimpedance spectroscopy in hemodialysis patients
J Appl Physiol 100: 717-724, 2006. First published October 27, 2005; doi:10.1152/japplphysiol.00669.2005 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

Kui Xu and Joseph C. LaManna

Invited Review  Chronic hypoxia and the cerebral circulation
J Appl Physiol 100: 725-730, 2006; doi:10.1152/japplphysiol.00940.2005 [Abstract] [Full Text] [PDF]  

William Pearce

Invited Review  Hypoxic regulation of the fetal cerebral circulation
J Appl Physiol 100: 731-738, 2006; doi:10.1152/japplphysiol.00990.2005 [Abstract] [Full Text] [PDF]  

Frank M. Faraci

Invited Review  Reactive oxygen species: influence on cerebral vascular tone
J Appl Physiol 100: 739-743, 2006; doi:10.1152/japplphysiol.01044.2005 [Abstract] [Full Text] [PDF]  

POINT-COUNTERPOINT

Bengt Saltin, José A. L. Calbet, and Peter D. Wagner

Point: In health and in a normoxic environment, O_{2 max} is limited primarily by cardiac output and locomotor muscle blood flow
J Appl Physiol 100: 744-748, 2006; doi:10.1152/japplphysiol.01395.2005 [Full Text] [PDF]  

POINT-COUNTERPOINT COMMENTS

José A L Calbet, Robert Boushel, and Carsten Lundby

Comment on Point:Counterpoint "Positive effects of intermittent hypoxia (live high:train low) on exercise performance are/are not mediated primarily by augmented red cell volume"
J Appl Physiol 100: 749-749, 2006; doi:10.1152/japplphysiol.01119.2005 [Full Text] [PDF]  

Takeshi Nishiyasu, Masachi Ichinose, Warren G. Guntheroth, and Heidi L. Collins

Comment on Point:Counterpoint "The muscle metaboreflex does/does not restore blood flow to contracting muscles"
J Appl Physiol 100: 750-751, 2006; doi:10.1152/japplphysiol.01342.2005 [Full Text] [PDF]  

CORRIGENDA

CORRIGENDUM
J Appl Physiol 100: 752-752, 2006; doi:10.1152/japplphysiol.01511.2005 [Full Text] [PDF]  

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