ESSAYS ON APS CLASSIC PAPERS

Robert A. Klocke

Editorial Focus  Dead space: Simplicity to complexity
J Appl Physiol 100: 1-2, 2006; doi:10.1152/classicessays.00037.2005 [Abstract] [Full Text] [PDF]  

EDITORIAL

Dale A. Pelligrino

Editorial
J Appl Physiol 100: 3-4, 2006; doi:10.1152/japplphysiol.01254.2005 [Full Text] [PDF]  

INVITED EDITORIAL

Alan R. Schwartz, Jason Kirkness, and Philip Smith

Extraluminal tissue pressure: what does it mean?
J Appl Physiol 100: 5-6, 2006; doi:10.1152/japplphysiol.01239.2005 [Full Text] [PDF]  

Louise M. Burke and Bente Kiens

"Fat adaptation" for athletic performance: the nail in the coffin?
J Appl Physiol 100: 7-8, 2006; doi:10.1152/japplphysiol.01238.2005 [Full Text] [PDF]  

Eugene Nattie

Why do we have both peripheral and central chemoreceptors?
J Appl Physiol 100: 9-10, 2006; doi:10.1152/japplphysiol.01097.2005 [Full Text] [PDF]  

Murray Esler and Nina Eikelis

Is obstructive sleep apnea the cause of sympathetic nervous activation in human obesity?
J Appl Physiol 100: 11-12, 2006; doi:10.1152/japplphysiol.01294.2005 [Full Text] [PDF]  

ARTICLES

C. A. Smith, J. R. Rodman, B. J. A. Chenuel, K. S. Henderson, and J. A. Dempsey

Response time and sensitivity of the ventilatory response to CO₂ in unanesthetized intact dogs: central vs. peripheral chemoreceptors
J Appl Physiol 100: 13-19, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00926.2005 [Abstract] [Full Text] [PDF]  

Fabrice Favret, Kyle K. Henderson, Julie Allen, Jean-Paul Richalet, and Norberto C. Gonzalez

Exercise training improves lung gas exchange and attenuates acute hypoxic pulmonary hypertension but does not prevent pulmonary hypertension of prolonged hypoxia
J Appl Physiol 100: 20-25, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00673.2005 [Abstract] [Full Text] [PDF]  

Alison R. Harmer, Patricia A. Ruell, Michael J. McKenna, Donald J. Chisholm, Sandra K. Hunter, Jeanette M. Thom, Norman R. Morris, and Jeff R. Flack

Effects of sprint training on extrarenal potassium regulation with intense exercise in Type 1 diabetes
J Appl Physiol 100: 26-34, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00240.2005 [Abstract] [Full Text] [PDF]  

Michael J. Toth, Philip A. Ades, Martin M. LeWinter, Russell P. Tracy, and André Tchernof

Skeletal muscle myofibrillar mRNA expression in heart failure: relationship to local and circulating hormones
J Appl Physiol 100: 35-41, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00570.2005 [Abstract] [Full Text] [PDF]  

Fumio Yamazaki, Ryoko Sone, Kun Zhao, Guy E. Alvarez, Wojciech A. Kosiba, and John M. Johnson

Rate dependency and role of nitric oxide in the vascular response to direct cooling in human skin
J Appl Physiol 100: 42-50, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00139.2005 [Abstract] [Full Text] [PDF]  

Shigehiko Ogoh, R. Matthew Brothers, Quinton Barnes, Wendy L. Eubank, Megan N. Hawkins, Sushmita Purkayastha, Albert O-Yurvati, and Peter B. Raven

Cardiopulmonary baroreflex is reset during dynamic exercise
J Appl Physiol 100: 51-59, 2006. First published September 8, 2005; doi:10.1152/japplphysiol.00804.2005 [Abstract] [Full Text] [PDF]  

Rurong Wang, Fadi Xu, Jianguo Zhuang, and Cancan Zhang

Carotid sinus nerve is involved in cardiorespiratory responses to intracarotid injection of capsaicin in the rat
J Appl Physiol 100: 60-66, 2006. First published September 8, 2005; doi:10.1152/japplphysiol.00302.2005 [Abstract] [Full Text] [PDF]  

Jennifer L. McCord, Julie M. Beasley, and John R. Halliwill

H₂-receptor-mediated vasodilation contributes to postexercise hypotension
J Appl Physiol 100: 67-75, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00959.2005 [Abstract] [Full Text] [PDF]  

Isidore C. Okere, Tracy A. McElfresh, Daniel Z. Brunengraber, Wenjun Martini, Joseph P. Sterk, Hazel Huang, Margaret P. Chandler, Henri Brunengraber, and William C. Stanley

Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion
J Appl Physiol 100: 76-82, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00255.2005 [Abstract] [Full Text] [PDF]  

Olle Lagerquist, E. Paul Zehr, and David Docherty

Increased spinal reflex excitability is not associated with neural plasticity underlying the cross-education effect
J Appl Physiol 100: 83-90, 2006; doi:10.1152/japplphysiol.00533.2005 [Abstract] [Full Text] [PDF]  

Catherine A. Mayer, Musa A. Haxhiu, Richard J. Martin, and Christopher G. Wilson

Adenosine A_2A receptors mediate GABAergic inhibition of respiration in immature rats
J Appl Physiol 100: 91-97, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00459.2005 [Abstract] [Full Text] [PDF]  

Flavia B. Santos, Lilian K. S. Nagato, Nicolau M. Boechem, Elnara M. Negri, Alberto Guimarães, Vera L. Capelozzi, Debora S. Faffe, Walter A. Zin, and Patricia R. M. Rocco

Time course of lung parenchyma remodeling in pulmonary and extrapulmonary acute lung injury
J Appl Physiol 100: 98-106, 2006. First published August 18, 2005; doi:10.1152/japplphysiol.00395.2005 [Abstract] [Full Text] [PDF]  

Jean-François Papon, Lydia Brugel-Ribere, Redouane Fodil, Céline Croce, Christian Larger, Michel Rugina, André Coste, Daniel Isabey, Françoise Zerah-Lancner, and Bruno Louis

Nasal wall compliance in vasomotor rhinitis
J Appl Physiol 100: 107-111, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00575.2005 [Abstract] [Full Text] [PDF]  

Matt M. Riordan and Sándor J. Kovács

Quantitation of mitral annular oscillations and longitudinal "ringing" of the left ventricle: a new window into longitudinal diastolic function
J Appl Physiol 100: 112-119, 2006. First published September 8, 2005; doi:10.1152/japplphysiol.00844.2005 [Abstract] [Full Text] [PDF]  

Bradley C. Nindl, Kevin R. Rarick, John W. Castellani, Alexander P. Tuckow, John F. Patton, Andrew J. Young, and Scott J. Montain

Altered secretion of growth hormone and luteinizing hormone after 84 h of sustained physical exertion superimposed on caloric and sleep restriction
J Appl Physiol 100: 120-128, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.01415.2004 [Abstract] [Full Text] [PDF]  

Espen E. Spangenburg and Todd A. McBride

Inhibition of stretch-activated channels during eccentric muscle contraction attenuates p70^S6K activation
J Appl Physiol 100: 129-135, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00619.2005 [Abstract] [Full Text] [PDF]  

R. A. Payne, C. N. Symeonides, D. J. Webb, and S. R. J. Maxwell

Pulse transit time measured from the ECG: an unreliable marker of beat-to-beat blood pressure
J Appl Physiol 100: 136-141, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00657.2005 [Abstract] [Full Text] [PDF]  

Loretta DiPietro, James Dziura, Catherine W. Yeckel, and P. Darrell Neufer

Exercise and improved insulin sensitivity in older women: evidence of the enduring benefits of higher intensity training
J Appl Physiol 100: 142-149, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00474.2005 [Abstract] [Full Text] [PDF]  

Asli F. Ceylan-Isik, Shan Wu, Qun Li, Shi-Yan Li, and Jun Ren

High-dose benfotiamine rescues cardiomyocyte contractile dysfunction in streptozotocin-induced diabetes mellitus
J Appl Physiol 100: 150-156, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00988.2005 [Abstract] [Full Text] [PDF]  

L. He, J. Chen, B. Dinger, L. Stensaas, and S. Fidone

Effect of chronic hypoxia on purinergic synaptic transmission in rat carotid body
J Appl Physiol 100: 157-162, 2006; doi:10.1152/japplphysiol.00859.2005 [Abstract] [Full Text] [PDF]  

Daniel P. Ferris, Zaineb A. Bohra, Jamie R. Lukos, and Catherine R. Kinnaird

Neuromechanical adaptation to hopping with an elastic ankle-foot orthosis
J Appl Physiol 100: 163-170, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00821.2005 [Abstract] [Full Text] [PDF]  

Ailiang Xie, James B. Skatrud, Dominic S. Puleo, and Jerome A. Dempsey

Influence of arterial O₂ on the susceptibility to posthyperventilation apnea during sleep
J Appl Physiol 100: 171-177, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00440.2005 [Abstract] [Full Text] [PDF]  

Nicholas A. Ryan, Kevin A. Zwetsloot, Lenna M. Westerkamp, Robert C. Hickner, Walter E. Pofahl, and Timothy P. Gavin

Lower skeletal muscle capillarization and VEGF expression in aged vs. young men
J Appl Physiol 100: 178-185, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00827.2005 [Abstract] [Full Text] [PDF]  

Harikrishnan Parameswaran, Arnab Majumdar, Satoru Ito, Adriano M. Alencar, and Béla Suki

Quantitative characterization of airspace enlargement in emphysema
J Appl Physiol 100: 186-193, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00424.2005 [Abstract] [Full Text] [PDF]  

L. Havemann, S. J. West, J. H. Goedecke, I. A. Macdonald, A. St Clair Gibson, T. D. Noakes, and E. V. Lambert

Fat adaptation followed by carbohydrate loading compromises high-intensity sprint performance
J Appl Physiol 100: 194-202, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00813.2005 [Abstract] [Full Text] [PDF]  

Julien V. Brugniaux, Laurent Schmitt, Paul Robach, Gérard Nicolet, Jean-Pierre Fouillot, Stéphane Moutereau, Françoise Lasne, Vincent Pialoux, Philippe Saas, Marie-Claude Chorvot, Jérémy Cornolo, Niels V. Olsen, and Jean-Paul Richalet

Eighteen days of "living high, training low" stimulate erythropoiesis and enhance aerobic performance in elite middle-distance runners
J Appl Physiol 100: 203-211, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00808.2005 [Abstract] [Full Text] [PDF]  

Xue-Qian Zhang, J. Randall Moorman, Belinda A. Ahlers, Lois L. Carl, Douglas E. Lake, Jianliang Song, J. Paul Mounsey, Amy L. Tucker, Yiu-mo Chan, Lawrence I. Rothblum, Richard C. Stahl, David J. Carey, and Joseph Y. Cheung

Phospholemman overexpression inhibits Na⁺-K⁺-ATPase in adult rat cardiac myocytes: relevance to decreased Na⁺ pump activity in postinfarction myocytes
J Appl Physiol 100: 212-220, 2006. First published September 29, 2005; doi:10.1152/japplphysiol.00757.2005 [Abstract] [Full Text] [PDF]  

Scott L. Davis, Paul J. Fadel, Jian Cui, Gail D. Thomas, and Craig G. Crandall

Skin blood flow influences near-infrared spectroscopy-derived measurements of tissue oxygenation during heat stress
J Appl Physiol 100: 221-224, 2006. First published September 8, 2005; doi:10.1152/japplphysiol.00867.2005 [Abstract] [Full Text] [PDF]  

James M. Williams and William J. Pearce

Age-dependent modulation of endothelium-dependent vasodilatation by chronic hypoxia in ovine cranial arteries
J Appl Physiol 100: 225-232, 2006. First published September 22, 2005; doi:10.1152/japplphysiol.00221.2005 [Abstract] [Full Text] [PDF]  

V. M. Dupouy, P. J. Ferre, E. Uro-Coste, and H. P. Lefebvre

Time course of COX-1 and COX-2 expression during ischemia-reperfusion in rat skeletal muscle
J Appl Physiol 100: 233-239, 2006; doi:10.1152/japplphysiol.00673.2004 [Abstract] [Full Text] [PDF]  

Johan Petersson, Malin Rohdin, Alejandro Sánchez-Crespo, Sven Nyrén, Hans Jacobsson, Stig A. Larsson, Sten G. E. Lindahl, Dag Linnarsson, Robb W. Glenny, and Margareta Mure

Paradoxical redistribution of pulmonary blood flow in prone and supine humans exposed to hypergravity
J Appl Physiol 100: 240-248, 2006. First published September 8, 2005; doi:10.1152/japplphysiol.01430.2004 [Abstract] [Full Text] [PDF]  

Theodore W. Zderic and Marc T. Hamilton

Physical inactivity amplifies the sensitivity of skeletal muscle to the lipid-induced downregulation of lipoprotein lipase activity
J Appl Physiol 100: 249-257, 2006. First published September 29, 2005; doi:10.1152/japplphysiol.00925.2005 [Abstract] [Full Text] [PDF]  

Jeff E. Sellman, Keith C. DeRuisseau, Jenna L. Betters, Vitor A. Lira, Quinlyn A. Soltow, Joshua T. Selsby, and David S. Criswell

In vivo inhibition of nitric oxide synthase impairs upregulation of contractile protein mRNA in overloaded plantaris muscle
J Appl Physiol 100: 258-265, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00936.2005 [Abstract] [Full Text] [PDF]  

V. G. Macefield, S. C. Gandevia, and L. A. Henderson

Neural sites involved in the sustained increase in muscle sympathetic nerve activity induced by inspiratory capacity apnea: a fMRI study
J Appl Physiol 100: 266-273, 2006. First published August 25, 2005; doi:10.1152/japplphysiol.00588.2005 [Abstract] [Full Text] [PDF]  

Takeshi Matsumoto, Masayuki Yoshino, Takahisa Asano, Kentaro Uesugi, Masahiro Todoh, and Masao Tanaka

Monochromatic synchrotron radiation µCT reveals disuse-mediated canal network rarefaction in cortical bone of growing rat tibiae
J Appl Physiol 100: 274-280, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00495.2005 [Abstract] [Full Text] [PDF]  

Claudia Fló, Fernanda D. T. Q. S. Lopes, David I. Kasahara, Anna Cecília D. Silva, Rita C. C. Jesus, Dolores H. R. F. Rivero, Paulo H. N. Saldiva, Milton A. Martins, and Wilson Jacob-Filho

Effects of exercise training on papain-induced pulmonary emphysema in Wistar rats
J Appl Physiol 100: 281-285, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.00024.2005 [Abstract] [Full Text] [PDF]  

Mitchell Sitnick, Andrea M. Foley, Marybeth Brown, and Espen E. Spangenburg

Ovariectomy prevents the recovery of atrophied gastrocnemius skeletal muscle mass
J Appl Physiol 100: 286-293, 2006. First published September 8, 2005; doi:10.1152/japplphysiol.00869.2005 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY

Khaled F. Mansour, James A. Rowley, and M. Safwan Badr

Measurement of pharyngeal cross-sectional area by finite element analysis
J Appl Physiol 100: 294-303, 2006. First published September 8, 2005; doi:10.1152/japplphysiol.00364.2005 [Abstract] [Full Text] [PDF]  

Gianluca A. A. M. Cammarata, Max Harry Weil, Michael Fries, Wanchun Tang, Shijie Sun, and Carlos J. Castillo

Buccal capnometry to guide management of massive blood loss
J Appl Physiol 100: 304-306, 2006. First published September 1, 2005; doi:10.1152/japplphysiol.01247.2004 [Abstract] [Full Text] [PDF]  

HIGHLIGHTED TOPICS

Raymond C. Koehler, Debebe Gebremedhin, and David R. Harder

Invited Review  Role of astrocytes in cerebrovascular regulation
J Appl Physiol 100: 307-317, 2006; doi:10.1152/japplphysiol.00938.2005 [Abstract] [Full Text] [PDF]  

Jon Andresen, Nadeem I. Shafi, and Robert M. Bryan, Jr.

Invited Review  Endothelial influences on cerebrovascular tone
J Appl Physiol 100: 318-327, 2006; doi:10.1152/japplphysiol.00937.2005 [Abstract] [Full Text] [PDF]  

Helene Girouard and Costantino Iadecola

Invited Review  Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease
J Appl Physiol 100: 328-335, 2006; doi:10.1152/japplphysiol.00966.2005 [Abstract] [Full Text] [PDF]  

Xinyue Qin, Herman Kwansa, Enrico Bucci, Richard J. Roman, and Raymond C. Koehler

Role of 20-HETE in the pial arteriolar constrictor response to decreased hematocrit after exchange transfusion of cell-free polymeric hemoglobin
J Appl Physiol 100: 336-342, 2006. First published September 15, 2005; doi:10.1152/japplphysiol.00890.2005 [Abstract] [Full Text] [PDF]  

Paul J. Mills, Brian P. Kennedy, Jose S. Loredo, Joel E. Dimsdale, and Michael G. Ziegler

Effects of nasal continuous positive airway pressure and oxygen supplementation on norepinephrine kinetics and cardiovascular responses in obstructive sleep apnea
J Appl Physiol 100: 343-348, 2006; doi:10.1152/japplphysiol.00494.2005 [Abstract] [Full Text] [PDF]  

Kristina Kairaitis, Rosie Stavrinou, Radha Parikh, John R. Wheatley, and Terence C. Amis

Mandibular advancement decreases pressures in the tissues surrounding the upper airway in rabbits
J Appl Physiol 100: 349-356, 2006. First published August 25, 2005; doi:10.1152/japplphysiol.00560.2005 [Abstract] [Full Text] [PDF]  

POINT-COUNTERPOINT

Donal S. O'Leary and Michael J. Joyner

Point: The muscle metaboreflex does restore blood flow to contracting muscles
J Appl Physiol 100: 357-361, 2006; doi:10.1152/japplphysiol.01222.2005 [Full Text] [PDF]  

POINT-COUNTERPOINT COMMENTS

Britta N. Torgrimson, Jessica R. Meendering, Christopher T. Minson, B. Geny, O. Rouyer, S. Doutreleau, and F. Piquard

Commentary on Point-Counterpoint
J Appl Physiol 100: 362-362, 2006; doi:10.1152/japplphysiol.01313.2005 [Full Text] [PDF]  

Stefan Keslacy, Robert S. Mazzeo, D. A. Giussani, A. S. Thakor, Giuseppe Insalaco, Maria Rosaria Bonsignore, Fernando A. Rodríguez, Karen S. Mark, C. Reboul, S. Tanguy, Leonhard Schaffer, Hugo H. Marti, Alfredo Gamboa, Jorge L. Gamboa, Jon Peter Wehrlin, Robert F. Grover, Birgit Friedmann, David T. Martin, Allan G. Hahn, George A. Brooks, Walter Schmidt, and Bernd Wolfarth

Commentary on Point-Counterpoint
J Appl Physiol 100: 363-363, 2006; doi:10.1152/japplphysiol.01156.2005 [Full Text] [PDF]  

A. William Sheel, Ferdinando Iellamo, Peter B. Raven, and Robert D. Wurster

Commentary on Point-Counterpoint
J Appl Physiol 100: 371-371, 2006; doi:10.1152/japplphysiol.01329.2005 [Full Text] [PDF]  

LETTERS TO THE EDITOR

Christopher T. Minson, Paul Kaplan, Jessica R. Meendering, Britta N. Torgrimson, and Nicole P. Miller

Comments on Women, hormones, and clinical trials: a beginning, not an end
J Appl Physiol 100: 373-373, 2006; doi:10.1152/japplphysiol.01183.2005 [Full Text] [PDF]  

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