HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Free Full Text (PDF) Free All Versions of this Article: 96/3/879    most recent 00532.2003v1 Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (2) Citing Articles via Google Scholar Google Scholar Articles by Lichtwarck-Aschoff, M. Articles by Guttmann, J. Search for Related Content PubMed PubMed Citation Articles by Lichtwarck-Aschoff, M. Articles by Guttmann, J.

Decreasing size of cardiogenic oscillations reflects decreasing compliance of the respiratory system during long-term ventilation

Departments of ¹Surgical and ³Medical Sciences, Uppsala University, 751 05 Uppsala, Sweden; ²Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215; and ⁴Department of Anaesthesiology and Critical Care Medicine, Freiburg University, 79085 Freiburg, Germany

Submitted 18 May 2003 ; accepted in final form 22 October 2003

Part of the energy produced by the heartbeat is transferred to the lung and promotes intrapulmonary gas mixing. It is likely that this transmission in the form of local mechanical disturbances affects and reflects respiratory mechanics. The effects of the cardiogenic oscillations were studied in seven piglets during 7 h of monotonous mechanical ventilation. During the 1st h of ventilation, every heartbeat triggered a noticeable transient increase in lung volume of 14 ml (95% confidence interval = 10-17 ml). After 7 h, the increase in lung volume due to heartbeat significantly decreased to 7 ml (95% confidence interval = 2-9 ml, P < 0.05). During the course of ventilation, overall lung compliance and gas exchange were progressively compromised. We conclude that 1) sufficient mechanical energy is transferred from the beating heart to the lung to increase lung volume, and 2) the ability of the heartbeats to help increase lung volume is reduced during long-term ventilation, which reflects the changes in lung compliance.

heart-lung interaction; cardiac cycle; heart motion

This article has been cited by other articles:

				S. Montmerle and D. Linnarsson Effects of gravity and blood volume shifts on cardiogenic oscillations in respired gas J Appl Physiol, September 1, 2005; 99(3): 931 - 936. [Abstract] [Full Text] [PDF]

				T. E. Dick, R. Shannon, B. G. Lindsey, S. C. Nuding, L. S. Segers, D. M. Baekey, and K. F. Morris Arterial pulse modulated activity is expressed in respiratory neural output J Appl Physiol, August 1, 2005; 99(2): 691 - 698. [Abstract] [Full Text] [PDF]