| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Department of Pulmonary Physiology, Sir Charles Gairdner Hospital; and 2 Departments of Human Movement and Exercise Science, and 3 Surgery, Centre for Musculoskeletal Studies, University of Western Australia, Australia 6009
Genioglossus (GG) electrical activity [measured by electromyogram (EMGgg)] is best measured by intramuscular electrodes; however, the homogeneity of EMGgg is undefined. We investigated the relationships between EMGgg and the site from which activity was measured to determine whether and to what extent inhomogeneity in activity occurred. Eight healthy human volunteers underwent ultrasound to determine GG depth and width. Four pairs of electrodes were then inserted percutaneously into the left and right GG muscle, anteriorly and posteriorly. Additional configurations were obtained by connecting electrodes across the midline and along each muscle belly. EMGgg activity was simultaneously recorded from these 10 configurations at rest and during various respiratory maneuvers. Heterogeneous behavior of the GG was evidenced by 1) the variable presence of phasic EMGgg at rest, which was undetectable in two subjects but evident in 65% of configurations in six subjects and present in all configurations in all subjects during voluntary hyperventilation; 2) a greater amplitude of EMGgg response to pharyngeal square-wave negative pressure in anterior than posterior configurations (14.1 ± 7.1 vs. 8.5 ± 5.1% of maximum, P < 0.05); and 3) variable (linear and alinear) relationships between EMGgg and lingual force within and between subjects. We hypothesize that regional differences in density and type of muscle fiber are the most likely sources of heterogeneity in these responses.
obstructive sleep apnoea; upper airway collapse; dilator; ultrasound
This article has been cited by other articles:
|
|
 |
|
  T. Tsukada, H. Taniguchi, S. Ootaki, Y. Yamada, and M. Inoue Effects of food texture and head posture on oropharyngeal swallowing J Appl Physiol, June 1, 2009; 106(6): 1848 - 1857. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. J. Pittman and E. F. Bailey Genioglossus and Intrinsic Electromyographic Activities in Impeded and Unimpeded Protrusion Tasks J Neurophysiol, January 1, 2009; 101(1): 276 - 282. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. J. Morrell Going to the movies can make all the difference J. Physiol., September 1, 2008; 586(17): 4035 - 4036. [Full Text] [PDF]
|
|
|
|
|
|
S. Cheng, J. E. Butler, S. C. Gandevia, and L. E. Bilston Movement of the tongue during normal breathing in awake healthy humans J. Physiol., September 1, 2008; 586(17): 4283 - 4294. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. S. Doherty, J. P. Cullen, P. Nolan, and W. T. McNicholas The human genioglossus response to negative airway pressure: stimulus timing and route of delivery Exp Physiol, February 1, 2008; 93(2): 288 - 295. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. F. Bailey, K. W. Fridel, and A. D. Rice Sleep/Wake Firing Patterns of Human Genioglossus Motor Units J Neurophysiol, December 1, 2007; 98(6): 3284 - 3291. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Saboisky, J. E. Butler, D. K. McKenzie, R. B. Gorman, J. A. Trinder, D. P. White, and S. C. Gandevia Neural drive to human genioglossus in obstructive sleep apnoea J. Physiol., November 15, 2007; 585(1): 135 - 146. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Eckert, R. D. McEvoy, K. E. George, K. J. Thomson, and P. G. Catcheside Genioglossus reflex inhibition to upper-airway negative-pressure stimuli during wakefulness and sleep in healthy males J. Physiol., June 15, 2007; 581(3): 1193 - 1205. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. F. Bailey, A. D. Rice, and A. J. Fuglevand Firing Patterns of Human Genioglossus Motor Units During Voluntary Tongue Movement J Neurophysiol, January 1, 2007; 97(1): 933 - 936. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Eikermann, F. M. Vogt, F. Herbstreit, M. Vahid-Dastgerdi, M. O. Zenge, C. Ochterbeck, A. de Greiff, and J. Peters The Predisposition to Inspiratory Upper Airway Collapse during Partial Neuromuscular Blockade Am. J. Respir. Crit. Care Med., January 1, 2007; 175(1): 9 - 15. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Saboisky, J. E. Butler, R. B. Fogel, J. L. Taylor, J. A. Trinder, D. P. White, and S. C. Gandevia Tonic and Phasic Respiratory Drives to Human Genioglossus Motoneurons During Breathing J Neurophysiol, April 1, 2006; 95(4): 2213 - 2221. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
