| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas 76107
We sought to test the hypothesis that
the carotid baroreflex (CBR) alters mean leg blood flow (LBF) and leg
vascular conductance (LVC) at rest and during exercise. In seven men
and one woman, 25 ± 2 (SE) yr of age, CBR control of LBF and LVC
was determined at rest and during steady-state one-legged knee
extension exercise at ~65% peak O2 uptake. The
application of 5-s pulses of +40 Torr neck pressure and 
60 Torr neck
suction significantly altered mean arterial pressure (MAP) and LVC both
at rest and during exercise. CBR-mediated changes in MAP were similar
between rest and exercise (P > 0.05). However,
CBR-mediated decreases in LVC (%change) to neck pressure were
attenuated in the exercising leg (16.4 ± 1.6%) compared with
rest (33 ± 2.1%) and the nonexercising leg (23.7 ± 1.9%)
(P < 0.01). These data suggest CBR control of blood
pressure is partially mediated by changes in leg vascular tone both at rest and during exercise. Furthermore, despite alterations in CBR-induced changes in LVC during exercise, CBR control of blood pressure was well maintained.
carotid baroreceptors; neck pressure; neck suction; functional sympatholysis; leg blood flow
This article has been cited by other articles:
|
|
 |
|
  S. Ogoh, J. P. Fisher, C. N. Young, P. B. Raven, and P. J. Fadel Transfer function characteristics of the neural and peripheral arterial baroreflex arcs at rest and during postexercise muscle ischemia in humans Am J Physiol Heart Circ Physiol, May 1, 2009; 296(5): H1416 - H1424. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 X. Shi, F. A. Schaller, N. Tierney, P. Chanthavong, S. Chen, P. B. Raven, and M. L. Smith Physically Active Lifestyle Enhances Vagal-Cardiac Function but Not Central Autonomic Neural Interaction in Elderly Humans Experimental Biology and Medicine, February 1, 2008; 233(2): 209 - 218. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. K. Pellinger and J. R. Halliwill Effect of propranolol on sympathetically mediated leg vasoconstriction in humans J. Physiol., September 1, 2007; 583(2): 797 - 809. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ichinose, S. Koga, N. Fujii, N. Kondo, and T. Nishiyasu Modulation of the spontaneous beat-to-beat fluctuations in peripheral vascular resistance during activation of muscle metaboreflex Am J Physiol Heart Circ Physiol, July 1, 2007; 293(1): H416 - H424. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. B Raven, P. J Fadel, and S. Ogoh Arterial baroreflex resetting during exercise: a current perspective Exp Physiol, January 1, 2006; 91(1): 37 - 49. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. W. Wray, A. Uberoi, L. Lawrenson, and R. S. Richardson Heterogeneous limb vascular responsiveness to shear stimuli during dynamic exercise in humans J Appl Physiol, July 1, 2005; 99(1): 81 - 86. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ichinose and T. Nishiyasu Muscle metaboreflex modulates the arterial baroreflex dynamic effects on peripheral vascular conductance in humans Am J Physiol Heart Circ Physiol, April 1, 2005; 288(4): H1532 - H1538. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ogoh, M. K. Dalsgaard, C. C. Yoshiga, E. A. Dawson, D. M. Keller, P. B. Raven, and N. H. Secher Dynamic cerebral autoregulation during exhaustive exercise in humans Am J Physiol Heart Circ Physiol, March 1, 2005; 288(3): H1461 - H1467. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Keller, S. Ogoh, S. Greene, A Olivencia-Yurvati, and P. B Raven Inhibition of KATP channel activity augments baroreflex-mediated vasoconstriction in exercising human skeletal muscle J. Physiol., November 15, 2004; 561(1): 273 - 282. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Keller, P. J Fadel, S. Ogoh, R. M. Brothers, M. Hawkins, A. Olivencia-Yurvati, and P. B Raven Carotid baroreflex control of leg vasculature in exercising and non-exercising skeletal muscle in humans J. Physiol., November 15, 2004; 561(1): 283 - 293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D. Delp and D. S. O'Leary Integrative control of the skeletal muscle microcirculation in the maintenance of arterial pressure during exercise J Appl Physiol, September 1, 2004; 97(3): 1112 - 1118. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. W. Wray, P. J. Fadel, D. M. Keller, S. Ogoh, M. Sander, P. B. Raven, and M. L. Smith Dynamic carotid baroreflex control of the peripheral circulation during exercise in humans J. Physiol., September 1, 2004; 559(2): 675 - 684. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. D. Thomas and S. S. Segal Neural control of muscle blood flow during exercise J Appl Physiol, August 1, 2004; 97(2): 731 - 738. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. W. Wray, P. J. Fadel, M. L. Smith, P. Raven, and M. Sander Inhibition of {alpha}-adrenergic vasoconstriction in exercising human thigh muscles J. Physiol., March 1, 2004; 555(2): 545 - 563. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ogoh, P. J Fadel, P. Nissen, O. Jans, C. Selmer, N. H Secher, and P. B Raven Baroreflex-mediated changes in cardiac output and vascular conductance in response to alterations in carotid sinus pressure during exercise in humans J. Physiol., July 1, 2003; 550(1): 317 - 324. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
