Journal of Applied Physiology AJP citation statistics
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

J Appl Physiol (June 20, 2003). doi:10.1152/japplphysiol.01095.2002
This Article
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
95/4/1394    most recent
01095.2002v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Blasi, A.
Right arrow Articles by Khoo, M. C.K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Blasi, A.
Right arrow Articles by Khoo, M. C.K.
Submitted on December 2, 2002
Accepted on June 13, 2003

Cardiovascular variability following arousal from sleep: Time-varying spectral analysis

Anna Blasi1, Javier Jo1, Edwin Valladares1, Barbara J. Morgan2, James B. Skatrud3, and Michael C.K. Khoo1*

1 Biomedical Engineering Department, University of Southern California, Los Angeles, CA, USA
2 Department of Orthopedics and Rehabilitation, University of Wisconsin, Madison, WI, USA
3 Department of Medicine, University of Wisconsin, Madison, WI, USA

* To whom correspondence should be addressed. E-mail: khoo{at}bmsr.usc.edu.

We performed time-varying spectral analyses of heart-rate variability (HRV) and blood pressure variability (BPV) recorded from 16 normal humans during acoustically-induced arousals from sleep. Time-varying autoregressive modeling was employed to estimate the time-courses of high-frequency HRV power (HFPRR), low-frequency HRV power (LFPRR), the ratio between low-frequency and high-frequency HRV power (LF/HF = LFPRR / HFPRR), and low-frequency power of systolic BPV (LFPSBP). To delineate the influence of respiration on HRV, we also computed respiratory airflow high-frequency power (HFPAF), the modified ratio of low-frequency to high-frequency HRV power (MLHR) and the average transfer gain between respiration and heart rate (GRSA). During cortical arousal, muscle sympathetic nerve activity (MSNA) and heart rate increased and returned rapidly to baseline, but SBP, LF/HF, LFPRR, MLHR and LFPSBP displayed increases that remained above baseline up to 40 s following arousal. HFPRR and HFPAF showed concommitant decreases to levels below baseline, whereas GRSA remained unchanged. These findings suggest that: (1) arousal-induced changes in parasympathetic activity are strongly coupled to respiratory pattern, (2) the sympathoexcitatory cardiovascular effects of arousal are relatively long-lasting and may accumulate if repetitive arousals occur in close succession.




This article has been cited by other articles:


Home page
 The Journal of RheumatologyHome page
R. D. CHERVIN, M. TEODORESCU, R. KUSHWAHA, A. M. DELINE, C. B. BRUCKSCH, C. RIBBENS-GRIMM, D. L. RUZICKA, P. K. STEIN, D. J. CLAUW, and L. J. CROFFORD
Objective Measures of Disordered Sleep in Fibromyalgia
J Rheumatol, September 1, 2009; 36(9): 2009 - 2016.
[Abstract] [Full Text] [PDF]

Home page
 Phil Trans R Soc AHome page
L. T Mainardi
On the quantification of heart rate variability spectral parameters using time-frequency and time-varying methods
Phil Trans R Soc A, January 28, 2009; 367(1887): 255 - 275.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
J. M. Golbin, V. K. Somers, and S. M. Caples
Obstructive Sleep Apnea, Cardiovascular Disease, and Pulmonary Hypertension
Proceedings of the ATS, February 15, 2008; 5(2): 200 - 206.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 1966 by the American Physiological Society.