This investigation evaluated training responses to prolonged electrical muscle stimulation (EMS) in sedentary adults. Fifteen healthy subjects (10m, 5f) with a sedentary lifestyle completed a 6-week training programme during which they completed an average of 29 1-hour EMS sessions. The form of EMS used by the subjects was capable of eliciting a cardiovascular exercise response without loading the limbs or joints. It achieved this by means of inducing rapid, rhythmical contractions in the large leg muscles. A crossover study design was employed with subjects undergoing their habitual activity levels during the non-training phase of the study. The training effect was evaluated by means of a treadmill test to determine peak aerobic capacity, a 6-minute walking distance test, and measurement of body mass index and quadriceps muscle strength. At baseline the mean values for peak VO2, 6-minute walking distance, quadriceps strength and BMI were 2.46±0.57L/min, 493.3±36.8m, 360.8±108.7N, and 26.9±3.4kg/m² respectively. Following training subjects demonstrated statistically significant improvements in all variables except BMI. Peak VO2 increased by an average of 0.24±0.16L/min (P<0.05), walking distance increased by 36.6±19.7 (P<0.005), quadriceps strength increased by 87.5±55.9N (P<0.005), whereas we did not observe a significant effect due to training on BMI (P>0.05). These results suggest that EMS can be used in sedentary adults to improve physical fitness. It may provide a viable alternative to more conventional forms of exercise in this population.