Journal of Applied Physiology AJP: Endocrinology and Metabolism
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J Appl Physiol (December 14, 2001). doi:10.1152/japplphysiol.00880.2001
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Articles in PresS, published online ahead of print December 14, 2001
J Appl Physiol, 10.1152/jap.00880.2001
Submitted on August 27, 2001
Accepted on December 13, 2001

Neuromuscular fatigue during a long duration cycling exercise

Romuald Lepers1*, Nicola A Maffiuletti1, Ludovic Rochette1, Julien Brugniaux1, and Guillaume Y Millet1

1 Faculte des Sciences du Sport, Universite de Bourgogne, Dijon, France

* To whom correspondence should be addressed. E-mail: romuald.lepers{at}u-bourgogne.fr.

The effects of prolonged cycling on neuromuscular parameters were studied in 9 endurance-trained subjects during a 5-h exercise sustained at 55% of the maximal aerobic power. Torque during maximal voluntary contraction (MVC) of the quadriceps muscle decreased progressively throughout the exercise (P < 0.01) and was 18% less at the end of exercise in comparison with the pre-exercise value. Peak twitch torque, contraction time and total area of mechanical response decreased significantly (P < 0.05) since the first hour of exercise. In contrast, changes in M-wave characteristics were significant only after the fourth hour of the exercise. Significant reductions (P < 0.05) in electromyographic activity normalized to the M-wave occurred after the first hour for the vastus lateralis muscle but only at the end of the exercise for the vastus medialis muscle. Muscle activation level, assessed by the twitch interpolation technique, decreased by 8% (P < 0.05) at the end of the exercise. The results suggest that the time course is such that the contractile properties are significantly altered since the first hour, while excitability and central drive are more impaired towards the latter stages of the 5-h cycling exercise.




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