Journal of Applied Physiology AJP: Heart and Circulatory Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

J Appl Physiol (September 12, 2003). doi:10.1152/japplphysiol.00650.2003
This Article
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
96/1/218    most recent
00650.2003v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nordlund, M. M
Right arrow Articles by Cresswell, A. G
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nordlund, M. M
Right arrow Articles by Cresswell, A. G
Submitted on June 23, 2003
Accepted on September 3, 2003

Central and peripheral contributions to fatigue in relation to level of activation during repeated maximal voluntary isometric plantar flexions

Maria M Nordlund1*, Alf Thorstensson1, and Andrew G Cresswell1

1 Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Sport and Health Sciences, University College of Physical Education and Sport, Stockholm, Sweden

* To whom correspondence should be addressed. E-mail: maria.nordlund{at}neuro.ki.se.

This study aimed to investigate central and peripheral contributions to fatigue during repeated maximal voluntary isometric plantar flexions. Changes in joint torque, level of activation (LOA) resting twitch amplitude (RT) electromyographic signals (EMG) and presynaptic inhibition of Ia-afferents were investigated during 9 bouts of 10 isometric maximal voluntary plantar flexions (MVCs). MVCs lasted for 2 s and were separated by 1 s. The interval between bouts was 10 s. Electrical stimulation was applied to the tibial nerve; at rest, to evoke RTs, M-waves and two (1.5 s interval) H-reflexes; with the soleus EMG at 30 % of that during MVC, to evoke M-waves and two H-reflexes; and during MVCs, to measure LOA. Over the 9 bouts, LOA decreased by 12.6 % and RT by 16.2 %. EMG-rms during MVCs remained unchanged for the soleus and tibialis anterior muscles, but decreased for medial gastrocnemius. Peripheral fatigue (decrease in RT) was positively correlated to LOA, whereas central fatigue (decrease in LOA) was not. Depression of both H-reflexes suggests that presynaptic inhibition after the 1st bout was partly induced by homosynaptic post activation depression of the Ia-terminal. The H-reflex to M-wave ratio increased with fatigue in both passive and active states with no change in the ratio of the 2nd H-reflex to the 1st, thereby indicating a decrease of presynaptic inhibition during fatigue. The results indicate that both central and peripheral mechanisms contributed to the fatigue observed during repeated maximal voluntary isometric plantar flexions, and that the development of peripheral fatigue was influenced by level of voluntary activation and initial plantar flexor torque.




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
M. Burnley
Estimation of critical torque using intermittent isometric maximal voluntary contractions of the quadriceps in humans
J Appl Physiol, March 1, 2009; 106(3): 975 - 983.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Sports. Med.Home page
A. Mendez-Villanueva, J. Fernandez-Fernandez, and D. Bishop
Exercise-induced homeostatic perturbations provoked by singles tennis match play with reference to development of fatigue
Br. J. Sports Med., November 1, 2007; 41(11): 717 - 722.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. Racinais, O. Girard, J. P. Micallef, and S. Perrey
Failed Excitability of Spinal Motoneurons Induced by Prolonged Running Exercise
J Neurophysiol, January 1, 2007; 97(1): 596 - 603.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Sports. Med.Home page
J P Weir, T W Beck, J T Cramer, T J Housh, T D Noakes, A St Clair Gibson, and E V Lambert
Is fatigue all in your head? A critical review of the central governor model * Commentary.
Br. J. Sports Med., July 1, 2006; 40(7): 573 - 586.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. M. Thomas, S. S. Cheung, G. C. Elder, and G. G. Sleivert
Voluntary muscle activation is impaired by core temperature rather than local muscle temperature
J Appl Physiol, April 1, 2006; 100(4): 1361 - 1369.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
N. Babault, K. Desbrosses, M.-S. Fabre, A. Michaut, and M. Pousson
Neuromuscular fatigue development during maximal concentric and isometric knee extensions
J Appl Physiol, March 1, 2006; 100(3): 780 - 785.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. Ushiyama, K. Masani, M. Kouzaki, H. Kanehisa, and T. Fukunaga
Difference in aftereffects following prolonged Achilles tendon vibration on muscle activity during maximal voluntary contraction among plantar flexor synergists
J Appl Physiol, April 1, 2005; 98(4): 1427 - 1433.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 1966 by the American Physiological Society.