| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Articles in PresS, published online ahead of print March 1, 2002
J Appl Physiol, 10.1152/jap.00553.2001
Submitted on June 1, 2001
Accepted on February 25, 2002
1 Sleep Research Laboratory, John D. Dingell VAMC, Detroit, MI, USA; Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University, Detroit, MI, USA
2 Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University, Detroit, MI, USA
* To whom correspondence should be addressed. E-mail: jrowley{at}intmed.wayne.edu.
It has been proposed that the gender difference in sleep apnea prevalence is related to gender differences in upper airway structure and function. We hypothesized that men would have smaller retropalatal cross-sectional area and higher compliance during sleep compared to women. Using upper airway imaging, we measured upper airway cross-sectional area and retropalatal compliance in wakefulness and NREM sleep in 15 men and 15 women without sleep-disordered breathing. Cross-sectional area at the beginning of inspiration tended to be larger in men compared to women in both wakefulness (194.5±21.3 mm2 v. 138.8±12.0 mm2, all data mean±SE) and NREM sleep (111.1±17.6 mm2 v. 83.3±11.9 mm2, p=0.058). There was no significant difference, however, after correction for body surface area. Retropalatal compliance also tended to be higher in men during both wakefulness (5.9±1.4 mm2/cmH2O v. 3.1±1.4 mm2/cmH2O, p=0.006) and NREM sleep (12.6±2.7 mm2/cmH2O v. 4.7±2.6 mm2/cmH2O, p=0.055). However, compliance was similar in men relative to women after correction for neck circumference. We conclude that the gender difference in retropalatal compliance is more accurately attributed to differences in neck circumference between the genders.
This article has been cited by other articles:
|
|
 |
|
  T. Ayuse, Y. Hoshino, S. Kurata, T. Ayuse, H. Schneider, J. P. Kirkness, S. P. Patil, A. R. Schwartz, and K. Oi The Effect of Gender on Compensatory Neuromuscular Response to Upper Airway Obstruction in Normal Subjects Under Midazolam General Anesthesia Anesth. Analg., October 1, 2009; 109(4): 1209 - 1218. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. G. Sankri-Tarbichi, J. A. Rowley, and M. S. Badr Expiratory Pharyngeal Narrowing during Central Hypocapnic Hypopnea Am. J. Respir. Crit. Care Med., February 15, 2009; 179(4): 313 - 319. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. P. Kirkness, A. R. Schwartz, H. Schneider, N. M. Punjabi, J. J. Maly, A. M. Laffan, B. M. McGinley, T. Magnuson, M. Schweitzer, P. L. Smith, et al. Contribution of male sex, age, and obesity to mechanical instability of the upper airway during sleep J Appl Physiol, June 1, 2008; 104(6): 1618 - 1624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. F. Mansour, J. A. Rowley, and M. S. Badr Measurement of pharyngeal cross-sectional area by finite element analysis J Appl Physiol, January 1, 2006; 100(1): 294 - 303. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. S. Jordan, A. Wellman, J. K. Edwards, K. Schory, L. Dover, M. MacDonald, S. R. Patel, R. B. Fogel, A. Malhotra, and D. P. White Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea J Appl Physiol, November 1, 2005; 99(5): 2020 - 2027. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. B. Abbott, L. F. Donnelly, B. J. Dardzinski, S. A. Poe, B. A. Chini, and R. S. Amin Obstructive Sleep Apnea: MR Imaging Volume Segmentation Analysis Radiology, September 1, 2004; 232(3): 889 - 895. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kairaitis, R. Parikh, R. Stavrinou, S. Garlick, J. P. Kirkness, J. R. Wheatley, and T. C. Amis Upper airway extraluminal tissue pressure fluctuations during breathing in rabbits J Appl Physiol, October 1, 2003; 95(4): 1560 - 1566. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Younes Contributions of Upper Airway Mechanics and Control Mechanisms to Severity of Obstructive Apnea Am. J. Respir. Crit. Care Med., September 15, 2003; 168(6): 645 - 658. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. R. Dancey, P. J. Hanly, C. Soong, B. Lee, J. Shepard Jr, and V. Hoffstein Gender Differences in Sleep Apnea: The Role of Neck Circumference Chest, May 1, 2003; 123(5): 1544 - 1550. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Wellman, A. Malhotra, R. B. Fogel, J. K. Edwards, K. Schory, and D. P. White Respiratory system loop gain in normal men and women measured with proportional-assist ventilation J Appl Physiol, January 1, 2003; 94(1): 205 - 212. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Malhotra, Y. Huang, R. B. Fogel, G. Pillar, J. K. Edwards, R. Kikinis, S. H. Loring, and D. P. White The Male Predisposition to Pharyngeal Collapse: Importance of Airway Length Am. J. Respir. Crit. Care Med., November 15, 2002; 166(10): 1388 - 1395. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
