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J Appl Physiol (May 11, 2006). doi:10.1152/japplphysiol.00442.2006
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Submitted on April 15, 2006
Accepted on May 8, 2006

Masterequation for dysnatremia or intractable abracadabra

Troels Ring1*

1 Nephrology, Aalborg Hospital, Aalborg, Denmark

* To whom correspondence should be addressed. E-mail: tring{at}gvdnet.dk.

Recently Nguyen and Kurtz published a new equation showing how Gibbs-Donnan equilibrium could influence the regulation of the serum sodium concentration. The validity and utility of the formulae may however be severely doubted as they are not clinically tractable and not substantiated by direct evidence. In contrast the evidence provided seems contrived.




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K. L. Dorrington
Master dysnatremia equation for Gibbs-Donnan equilibrium and plasma sodium concentration: proof or spoof?
J Appl Physiol, February 1, 2008; 104(2): 569 - 569.
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