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Corrigendum for Messonnier et al., J Appl Physiol 102 (5) 1936-1944.
J Appl Physiol 104: 318, 2008; doi:10.1152/japplphysiol.zdg-7668-corr.2007
8750-7587/08 $8.00
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CORRIGENDUM

Corrigendum

Volume 102, May 2007 Messonnier L, Kristensen M, Juel C, Denis C. J Appl Physiol 102: 1936-1944, 2007; doi:10.1152/japplphysiol.00691.2006. Importance of pH regulation and lactate/H+ transport capacity for work production during supramaximal exercise in humans.

Regretfully, the paper contains several oversights. These corrections are a response, in part, to some points raised in a recent Letter to the Editor (1, 2).

On page 1938, left column, sentences lines 1–3 and 9–10, the authors omitted to mention that a fingertip blood sample was collected before and after exercise. The sentences should read respectively as follows: "After another 10 min of rest, the first muscle biopsy of the vastus lateralis and fingertip and arterial blood samples were taken to determine resting muscle and blood pH and lactate concentrations" and "Fingertip and arterial blood samples were also taken to determine pH and [Lac]b at the end of exercise."

On page 1939, right column, sentence lines 20–22, postexercise [Lac]b should be replaced by {Delta}[Lac]b. The sentence should read as follows: "The membrane-bound CAIV isoform content was positively correlated with {Delta}[Lac]b (Fig. 4A) and Wtot (Fig. 4C)."

On page 1941, legend of Fig. 4, [Lac]b and [Lac]m should be replaced by {Delta}[Lac]b and {Delta}[Lac]m, respectively. The first sentence of the legend should read as follows: "Relationships between muscle content of isoform IV of carbonic anhydrase (CAIV; arbitrary units) and {Delta}[Lac]b (mmol/l) (A) and {Delta}[Lac]m (mmol/kg dry wt) (B) at the end of the standardized exercise and total work performed (Wtot; kJ) (C) during supramaximal exercise until exhaustion."

It was demonstrated that the correlations reported in Fig. 1 are spurious. This entails several changes in the paper.

Abstract, lines 19–22, the correlations are reported and this should be removed from the text. The sentence should read as follows: "In Con, Wsup was positively correlated with MCT1, and tended to be positively correlated with MCT4 and NHE1".

Fig. 1 should be removed from the paper.

Results, page 1939, right column, lines 8–11: "The decreases in pHm and muscle lactate accumulation per joule of supramaximal work in CON ({Delta}pHm/Wsup-se and {Delta}[Lac]m/Wsup-se, respectively) were correlated with Wsup (Fig. 1)" should be removed.

Discussion, page 1941, left column, lines 13–17, mention of the correlations should be removed from the text. The sentence should read as follows: "The main result of this study is that the supramaximal work capacity is or tended to be positively associated with the muscle contents of MCT1, MCT4, and NHE1."

Discussion, page 1941, right column, lines 7–12: "Wsup was correlated with pHm decrease and [Lac]m accumulation per joule of Wsup-se (Fig. 1). The slower the decrease of pH and accumulation of lactate in the exercising muscles, the higher the Wsup. The present results suggest that pHm regulation and lactate removal may be crucial determinants of a subject's ability to perform supramaximal exercise." should be removed.

The authors apologize to The Journal of Applied Physiology, the reviewers, and the readers for these oversights.

REFERENCES

  1. Bishop D. Is supramaximal work capacity negatively correlated with the rate of decrease in muscle pH? J Appl Physiol 103: 1911, 2007.[Free Full Text]
  2. Messonnier L, Denis C. Reply to Dr. Bishop. J Appl Physiol 103: 1912–1913, 2007.[Free Full Text]




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