Journal of Applied Physiology Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 99: 1189-1192, 2005. First published May 5, 2005; doi:10.1152/japplphysiol.00283.2005
8750-7587/05 $8.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
99/3/1189    most recent
00283.2005v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (5)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kalliokoski, K. K.
Right arrow Articles by Kjaer, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kalliokoski, K. K.
Right arrow Articles by Kjaer, M.

The effect of dynamic knee-extension exercise on patellar tendon and quadriceps femoris muscle glucose uptake in humans studied by positron emission tomography

Kari K. Kalliokoski,1 Henning Langberg,1 Ann Kathrine Ryberg,1 Celena Scheede-Bergdahl,2 Simon Doessing,1 Andreas Kjaer,3 Robert Boushel,1,4 and Michael Kjaer1

Copenhagen Muscle Research Centre, 1Institute of Sports Medicine, Bispebjerg Hospital, 2Department of Medical Physiology, Panum Institute, University of Copenhagen; 3Department of Clinical Physiology, Nuclear Medicine, and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; and 4Department of Exercise Science, Concordia University, Montreal, Canada

Submitted 9 March 2005 ; accepted in final form 28 April 2005

ABSTRACT

Both tendon and peritendinous tissue show evidence of metabolic activity, but the effect of acute exercise on substrate turnover is unknown. We therefore examined the influence of acute exercise on glucose uptake in the patellar and quadriceps tendons during dynamic exercise in humans. Glucose uptake was measured in five healthy men in the patellar and quadriceps tendons and the quadriceps femoris muscle at rest and during dynamic knee-extension exercise (25 W) using positron emission tomography and [18F]-2-fluoro-2-deoxy-D-glucose ([18F]FDG). Glucose uptake index was calculated by dividing the tissue activity with blood activity of [18F]FDG. Exercise increased glucose uptake index by 77% in the patellar tendon (from 0.30 ± 0.09 to 0.51 ± 0.16, P = 0.03), by 106% in the quadriceps tendon (from 0.37 ± 0.15 to 0.75 ± 0.36, P = 0.02), and by 15-fold in the quadriceps femoris muscle (from 0.31 ± 0.11 to 4.5 ± 1.7, P = 0.005). The exercise-induced increase in the glucose uptake in neither tendon correlated with the increase in glucose uptake in the quadriceps muscle (r = –0.10, P = 0.87 for the patellar tendon and r = –0.30, P = 0.62 for the quadriceps tendon). These results show that tendon glucose uptake is increased during exercise. However, the increase in tendon glucose uptake is less pronounced than in muscle and the increases are uncorrelated. Thus tendon glucose uptake is likely to be regulated by mechanisms independently of those regulating skeletal muscle glucose uptake.

metabolism; connective tissue; imaging


Address for reprint requests and other correspondence: K. Kalliokoski, Turku PET Centre, Univ. of Turku, Kiinamyllynkatu 4–8, FIN-20520 Turku, Finland (e-mail: kari.kalliokoski{at}tyks.fi)




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
C. Couppe, P. Hansen, M. Kongsgaard, V. Kovanen, C. Suetta, P. Aagaard, M. Kjaer, and S. P. Magnusson
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men
J Appl Physiol, September 1, 2009; 107(3): 880 - 886.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. Couppe, M. Kongsgaard, P. Aagaard, P. Hansen, J. Bojsen-Moller, M. Kjaer, and S. P. Magnusson
Habitual loading results in tendon hypertrophy and increased stiffness of the human patellar tendon
J Appl Physiol, September 1, 2008; 105(3): 805 - 810.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
S. P. Magnusson, M. V. Narici, C. N. Maganaris, and M. Kjaer
Human tendon behaviour and adaptation, in vivo
J. Physiol., January 1, 2008; 586(1): 71 - 81.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
T. A. Trappe, C. C. Carroll, B. Jemiolo, S. W. Trappe, S. Dossing, M. Kjaer, and S. P. Magnusson
Cyclooxygenase mRNA expression in human patellar tendon at rest and after exercise
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2008; 294(1): R192 - R199.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. Bojsen-Moller, K. K. Kalliokoski, M. Seppanen, M. Kjaer, and S. P. Magnusson
Low-intensity tensile loading increases intratendinous glucose uptake in the Achilles tendon
J Appl Physiol, July 1, 2006; 101(1): 196 - 201.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2005 by the American Physiological Society.