Journal of Applied Physiology AJP: Lung Cellular and Molecular Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 96: 974-980, 2004. First published November 21, 2003; doi:10.1152/japplphysiol.01003.2003
8750-7587/04 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
96/3/974    most recent
01003.2003v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (6)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Turner, N.
Right arrow Articles by Hawley, J. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Turner, N.
Right arrow Articles by Hawley, J. A.

Greater effect of diet than exercise training on the fatty acid profile of rat skeletal muscle

Nigel Turner,1,2 Jong Sam Lee,3 Clinton R. Bruce,3 Todd W. Mitchell,1,2 Paul L. Else,1,2 A. J. Hulbert,1,4 and John A. Hawley3

1Metabolic Research Centre and Departments of 2Biomedical and 4Biological Sciences, University of Wollongong, Wollongong, New South Wales 2522; and 3Exercise Metabolism Group, School of Medical Sciences, RMIT University, Bundoora, Victoria 3083, Australia

Submitted 15 September 2003 ; accepted in final form 17 November 2003

We determined the interaction of diet and exercise-training intensity on membrane phospholipid fatty acid (FA) composition in skeletal muscle from 36 female Sprague-Dawley rats. Animals were randomly divided into one of two dietary conditions: high-carbohydrate (64.0% carbohydrate by energy, n = 18) or high fat (78.1% fat by energy, n = 18). Rats in each diet condition were then allocated to one of three subgroups: control, which performed no exercise training; low-intensity (8 m/min) treadmill run training; or high-intensity (28 m/min) run training. All exercise-trained rats ran 1,000 m/session, 4 days/wk for 8 wk and were killed 48 h after the last training bout. Membrane phospholipids were extracted, and FA composition was determined in the red and white vastus lateralis muscles. Diet exerted a major influence on phospholipid FA composition, with the high-fat diet being associated with a significantly (P < 0.01) elevated ratio of n-6/n-3 FA for both red (2.7–3.2 vs. 1.0–1.1) and white vastus lateralis muscle (2.5–2.9 vs. 1.2). In contrast, alterations in FA composition as a result of either exercise-training protocol were only minor in comparison. We conclude that, under the present experimental conditions, a change in the macronutrient content of the diet was a more potent modulator of skeletal muscle membrane phospholipid FA composition compared with either low- or high-intensity treadmill exercise training.

phospholipids; training; dietary fat; insulin sensitivity


Address for reprint requests and other correspondence: J. A. Hawley, Exercise Metabolism Group, School of Medical Sciences, RMIT Univ., PO Box 71, Bundoora, Victoria 3083, Australia (E-mail: john.hawley{at}rmit.edu.au).




This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
A. Ocloo, I. G. Shabalina, J. Nedergaard, and M. D. Brand
Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1
Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2007; 293(3): R1086 - R1093.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
D. Maillet and J.-M. Weber
Relationship between n-3 PUFA content and energy metabolism in the flight muscles of a migrating shorebird: evidence for natural doping
J. Exp. Biol., February 1, 2007; 210(3): 413 - 420.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
D. Maillet and J.-M. Weber
Performance-enhancing role of dietary fatty acids in a long-distance migrant shorebird: the semipalmated sandpiper
J. Exp. Biol., July 15, 2006; 209(14): 2686 - 2695.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
A. S. JANUSZEWSKI, A. J. JENKINS, J. W. BAYNES, and S. R. THORPE
Lipid-Derived Modifications of Plasma Proteins in Experimental and Human Diabetes
Ann. N.Y. Acad. Sci., June 1, 2005; 1043(1): 404 - 412.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
T. W. Mitchell, N. Turner, A. J. Hulbert, P. L. Else, J. A. Hawley, J. S. Lee, C. R. Bruce, and S. J. Blanksby
Exercise alters the profile of phospholipid molecular species in rat skeletal muscle
J Appl Physiol, November 1, 2004; 97(5): 1823 - 1829.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2004 by the American Physiological Society.