Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 96: 943-950, 2004. First published November 14, 2003; doi:10.1152/japplphysiol.00745.2003
8750-7587/04 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
96/3/943    most recent
00745.2003v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (9)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Battram, D. S.
Right arrow Articles by Graham, T. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Battram, D. S.
Right arrow Articles by Graham, T. E.

Caffeine ingestion does not impede the resynthesis of proglycogen and macroglycogen after prolonged exercise and carbohydrate supplementation in humans

D. S. Battram,1 J. Shearer,1 D. Robinson,2 and T. E. Graham1

1Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1; and 2Department of Family Medicine, Guelph General Hospital, Guelph, Ontario, Canada N1E 4J4

Submitted 17 July 2003 ; accepted in final form 7 November 2003

The purpose of this study was to examine the effects of caffeine (Caf) ingestion on pro- (PG) and macroglycogen (MG) resynthesis in 10 healthy men. Subjects completed two trials, consisting of a glycogen-depleting exercise, while ingesting either Caf or placebo capsules. Throughout recovery, biopsies were taken at 0 (exhaustion), 30, 120, and 300 min, and 75 g of carbohydrate were ingested at 0, 60, 120, 180, and 240 min. Whereas Caf ingestion resulted in a higher blood glucose concentration and decreased glycogen synthase fractional velocity (P <= 0.05), no effect was observed in either the amount or rate of PG and MG resynthesis. PG concentration increased significantly at each time point during recovery, whereas MG concentration remained unchanged until 120 min. The net rate of PG resynthesis was 115 mmol·kg dw-1·h-1 during the first 30 min of recovery, and then it significantly decreased by 62% throughout the remaining 4.5 h of recovery. The net rate of MG resynthesis was 77% lower than the net rate of PG resynthesis during the first 30 min of recovery and remained constant throughout 5 h of recovery despite increasing levels of insulin. In conclusion, Caf ingestion does not impede the resynthesis of PG or MG after an extensive depletion of muscle glycogen and with the provision of exogenous dietary carbohydrate.

glycogen synthase; insulin; recovery


Address for reprint requests and other correspondence: D. S. Battram, Dept. of Human Biology and Nutritional Sciences, Univ. of Guelph, Guelph, ON, Canada N1G 2W1 (E-mail: dbattram{at}uoguelph.ca).




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
D. J. Pedersen, S. J. Lessard, V. G. Coffey, E. G. Churchley, A. M. Wootton, T. Ng, M. J. Watt, and J. A. Hawley
High rates of muscle glycogen resynthesis after exhaustive exercise when carbohydrate is coingested with caffeine
J Appl Physiol, July 1, 2008; 105(1): 7 - 13.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Sports. Med.Home page
A. Bassini-Cameron, E. Sweet, A. Bottino, C. Bittar, C. Veiga, L.-C. Cameron, and E. H M Dantas
Effect of caffeine supplementation on haematological and biochemical variables in elite soccer players under physical stress conditions * COMMENTARY
Br. J. Sports Med., August 1, 2007; 41(8): 523 - 530.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
R. J. Wilson, J. E. Gusba, D. L. Robinson, and T. E. Graham
Glycogenin protein and mRNA expression in response to changing glycogen concentration in exercise and recovery
Am J Physiol Endocrinol Metab, June 1, 2007; 292(6): E1815 - E1822.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
I. Marchand, M. Tarnopolsky, K. B. Adamo, J. M. Bourgeois, K. Chorneyko, and T. E. Graham
Quantitative assessment of human muscle glycogen granules size and number in subcellular locations during recovery from prolonged exercise
J. Physiol., April 15, 2007; 580(2): 617 - 628.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
J. Shearer, R. Wilson, and T. Graham
Rebuttal to Abram Katz's Letter To The Editor
Am J Physiol Endocrinol Metab, April 1, 2006; 290(4): E758 - E759.
[Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S. E. Yeo, R. L. P. G. Jentjens, G. A. Wallis, and A. E. Jeukendrup
Caffeine increases exogenous carbohydrate oxidation during exercise
J Appl Physiol, September 1, 2005; 99(3): 844 - 850.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. Shearer, T. E. Graham, D. S. Battram, D. L. Robinson, E. A. Richter, R. J. Wilson, and M. Bakovic
Glycogenin activity and mRNA expression in response to volitional exhaustion in human skeletal muscle
J Appl Physiol, September 1, 2005; 99(3): 957 - 962.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
J. Shearer, R. J. Wilson, D. S. Battram, E. A. Richter, D. L. Robinson, M. Bakovic, and T. E. Graham
Increases in glycogenin and glycogenin mRNA accompany glycogen resynthesis in human skeletal muscle
Am J Physiol Endocrinol Metab, September 1, 2005; 289(3): E508 - E514.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2004 by the American Physiological Society.