Journal of Applied Physiology Ad Instruments
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 96: 463-468, 2004. First published August 29, 2003; doi:10.1152/japplphysiol.00292.2003
8750-7587/04 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
96/2/463    most recent
00292.2003v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (14)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Laffon, E.
Right arrow Articles by Marthan, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Laffon, E.
Right arrow Articles by Marthan, R.

A computed method for noninvasive MRI assessment of pulmonary arterial hypertension

Eric Laffon,1,2 Christophe Vallet,3 Virginie Bernard,4 Michel Montaudon,5 Dominique Ducassou,1 François Laurent,2,5 and Roger Marthan2

Service de 1Médecine Nucléaire, 4Cardiologie, and 5Radiologie, Hôpital du Haut-Lévêque, 33604 Pessac; 2Laboratoire de Physiologie Cellulaire Respiratoire, Institut National de la Santé et de la Recherche Médicale E 356, Université Victor Segalen Bordeaux 2, 33076 Bordeaux Cedex; and 3École Nationale Supérieure Électronique, Informatique et Radiocommunications, 33402 Talence Cedex, France

Submitted 20 March 2003 ; accepted in final form 28 August 2003

The present method enables the noninvasive assessment of mean pulmonary arterial pressure from magnetic resonance phase mapping by computing both physical and biophysical parameters. The physical parameters include the mean blood flow velocity over the cross-sectional area of the main pulmonary artery (MPA) at the systolic peak and the maximal systolic MPA cross-sectional area value, whereas the biophysical parameters are related to each patient, such as height, weight, and heart rate. These parameters have been measured in a series of 31 patients undergoing right-side heart catheterization, and the computed mean pulmonary arterial pressure value (PpaComp) has been compared with the mean pressure value obtained from catheterization (PpaCat) in each patient. A significant correlation was found that did not differ from the identity line PpaComp = PpaCat (r = 0.92). The mean and maximal absolute differences between PpaComp and PpaCat were 5.4 and 11.9 mmHg, respectively. The method was also applied to compute the MPA systolic and diastolic pressures in the same patient series. We conclude that this computed method, which combines physical (whoever the patient) and biophysical parameters (related to each patient), improves the accuracy of MRI to noninvasively estimate pulmonary arterial pressures.

pulmonary arterial hypertension; magnetic resonance phase mapping; computing; pulmonary arterial blood pressures


Address for reprint requests and other correspondence: E. Laffon, Service de Médecine Nucléaire, Hôpital du Haut-Lévêque, 33604 Pessac, France (E-mail: elaffon{at}u-bordeaux2.fr).




This article has been cited by other articles:


Home page
 Eur Respir JHome page
L. E. R. McLure and A. J. Peacock
Cardiac magnetic resonance imaging for the assessment of the heart and pulmonary circulation in pulmonary hypertension
Eur. Respir. J., June 1, 2009; 33(6): 1454 - 1466.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
M.-P. Revel, J.-B. Faivre, M. Remy-Jardin, V. Delannoy-Deken, A. Duhamel, and J. Remy
Pulmonary Hypertension: ECG-gated 64-Section CT Angiographic Evaluation of New Functional Parameters as Diagnostic Criteria
Radiology, February 1, 2009; 250(2): 558 - 566.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. Benza, R. Biederman, S. Murali, and H. Gupta
Role of Cardiac Magnetic Resonance Imaging in the Management of Patients With Pulmonary Arterial Hypertension
J. Am. Coll. Cardiol., November 18, 2008; 52(21): 1683 - 1692.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc ImagingHome page
G. Reiter, U. Reiter, G. Kovacs, B. Kainz, K. Schmidt, R. Maier, H. Olschewski, and R. Rienmueller
Magnetic Resonance-Derived 3-Dimensional Blood Flow Patterns in the Main Pulmonary Artery as a Marker of Pulmonary Hypertension and a Measure of Elevated Mean Pulmonary Arterial Pressure
Circ Cardiovasc Imaging, July 1, 2008; 1(1): 23 - 30.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart J SupplHome page
A. Vonk-Noordegraaf, J.-W. Lankhaar, M. J.W. Gotte, J. T. Marcus, P. E. Postmus, and N. Westerhof
Magnetic resonance and nuclear imaging of the right ventricle in pulmonary arterial hypertension
Eur. Heart J. Suppl., December 1, 2007; 9(suppl_H): H29 - H34.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
J. Sanz, P. Kuschnir, T. Rius, R. Salguero, R. Sulica, A. J. Einstein, S. Dellegrottaglie, V. Fuster, S. Rajagopalan, and M. Poon
Pulmonary Arterial Hypertension: Noninvasive Detection with Phase-Contrast MR Imaging
Radiology, April 1, 2007; 243(1): 70 - 79.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J.-W. Lankhaar, A. V. Noordegraaf, J. T. Marcus, E. Laffon, C. Vallet, V. Bernard, M. Montaudon, D. Ducassou, F. Laurent, and R. Marthan
A computed method for noninvasive MRI assessment of pulmonary arterial hypertension
J Appl Physiol, August 1, 2004; 97(2): 794 - 795.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2004 by the American Physiological Society.