HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Free Full Text (PDF) Free All Versions of this Article: 95/3/1076    most recent 00082.2002v1 Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (13) Citing Articles via Google Scholar Google Scholar Articles by Hanel, B. Articles by Mortensen, J. Search for Related Content PubMed PubMed Citation Articles by Hanel, B. Articles by Mortensen, J.

Maximal rowing has an acute effect on the blood-gas barrier in elite athletes

¹Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet, and ²Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Hvidovre Hospital, DK-2100 Copenhagen, Denmark

Submitted 31 January 2002 ; accepted in final form 22 April 2003

The purpose of the study was to evaluate the effects of maximal exercise on the integrity of the alveolar epithelial membrane using the clearance rate of aerosolized ^99mTc-labeled diethylenetriaminepentaacetic acid as an index for the permeability of the lung blood-gas barrier. Ten elite rowers (24.3 ± 4.6 yr of age) completed two 20-min pulmonary clearance measurements immediately after and 2 h after 6 min of all-out rowing (initial and late, respectively). All subjects participated in resting control measurements on a separate day. For each 20-min measurement, lung clearance was calculated for 0-7 and 10-20 min. Furthermore, scintigrams were processed from the initial and late measurements of diethylenetriaminepentaacetic acid clearance. Compared with control levels, the pulmonary clearance measurement after rowing was increased from 1.2 ± 0.5 to 2.4 ± 1.0%/min (SD) at 0-7 min (P < 0.01) and from 0.8 ± 0.3 to 1.5 ± 0.4%/min at 10-20 min (P < 0.0005), returning to resting levels within 2 h. In 6 of 10 subjects, ventilation distribution on the lung scintigrams was inhomogeneous at the initial measurement. The study demonstrates an acute increased pulmonary clearance after maximal rowing. The ventilation defects identified on the lung scintigrams may represent transient interstitial edema secondary to increased blood-gas barrier permeability induced by mechanical stress.

lung function; oarsmen; ventilation defects

This article has been cited by other articles:

				Final Report on the Safety Assessment of Pentasodium Pentetate and Pentetic Acid as Used in Cosmetics International Journal of Toxicology, March 1, 2008; 27(2_suppl): 71 - 92. [Abstract] [Full Text] [PDF]

				R. R. Watson, Z. Fu, and J. B. West Morphometry of the extremely thin pulmonary blood-gas barrier in the chicken lung Am J Physiol Lung Cell Mol Physiol, March 1, 2007; 292(3): L769 - L777. [Abstract] [Full Text] [PDF]

				M. K. Stickland, R. C. Welsh, M. J. Haykowsky, S. R. Petersen, W. D. Anderson, D. A. Taylor, M. Bouffard, and R. L. Jones Effect of acute increases in pulmonary vascular pressures on exercise pulmonary gas exchange J Appl Physiol, June 1, 2006; 100(6): 1910 - 1917. [Abstract] [Full Text] [PDF]

				M. W. Eldridge, R. K. Braun, K. Y. Yoneda, and W. F. Walby Effects of altitude and exercise on pulmonary capillary integrity: evidence for subclinical high-altitude pulmonary edema J Appl Physiol, March 1, 2006; 100(3): 972 - 980. [Abstract] [Full Text] [PDF]

				M. Vengust, H. Staempfli, L. Viel, and G. Heigenhauser Transvascular fluid flux from the pulmonary vasculature at rest and during exercise in horses J. Physiol., January 15, 2006; 570(2): 397 - 405. [Abstract] [Full Text] [PDF]

				Y. Adir, A. Shupak, A. Gil, N. Peled, Y. Keynan, L. Domachevsky, and D. Weiler-Ravell Swimming-Induced Pulmonary Edema: Clinical Presentation and Serial Lung Function Chest, August 1, 2004; 126(2): 394 - 399. [Abstract] [Full Text] [PDF]