Journal of Applied Physiology Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 92: 1611-1618, 2002. First published December 21, 2001; doi:10.1152/japplphysiol.00892.2001
8750-7587/02 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow All Versions of this Article:
92/4/1611    most recent
00892.2001v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (17)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nindl, B. C.
Right arrow Articles by Mello, R. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nindl, B. C.
Right arrow Articles by Mello, R. P.
Vol. 92, Issue 4, 1611-1618, April 2002

Gender differences in regional body composition and somatotrophic influences of IGF-I and leptin

Bradley C. Nindl, Charles R. Scoville, Kathleen M. Sheehan, Cara D. Leone, and Robert P. Mello

Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760

This study evaluated the arm, trunk, and leg for fat mass, lean soft tissue mass, and bone mineral content (BMC) assessed via dual-energy X-ray absorptiometry in a group of age-matched (~29 yr) men (n = 57) and women (n = 63) and determined their relationship to insulin-like growth factor I (IGF-I) and leptin. After analysis of covariance adjustment to control for differences in body mass between genders, the differences that persisted (P <=  0.05) were for lean soft tissue mass of the arm (men: 7.1 kg vs. women: 6.4 kg) and fat mass of the leg (men: 5.3 kg vs. women: 6.8 kg). Men and women had similar (P >=  0.05) values for fat mass of the arms and trunk and lean soft tissue mass of the legs and trunk. Serum IGF-I and insulin-like growth factor binding protein-3 correlated (P <=  0.05) with all measures of BMC (r values ranged from 0.31 to 0.39) and some measures of lean soft tissue mass for women (r = 0.30) but not men. Leptin correlated (P <=  0.05) similarly for measures of fat mass for both genders (r values ranging from 0.74 to 0.85) and for lean soft tissue mass of the trunk (r = 0.40) and total body (r = 0.32) for men and for the arms in women (r = 0.56). These data demonstrate that 1) the main phenotypic gender differences in body composition are that men have more of their muscle mass in their arms and women have more of their fat mass in their legs and 2) gender differences exist in the relationship between somatotrophic hormones and lean soft tissue mass.

appendicular skeletal muscle; adiposity; somatotrophic hormones; military personnel; insulin-like growth factor I


This article has been cited by other articles:


Home page
 Br. J. Sports. Med.Home page
C. Perret and G. Mueller
Impact of low-intensity isocapnic hyperpnoea on blood lactate disappearance after exhaustive arm exercise
Br. J. Sports Med., September 1, 2007; 41(9): 588 - 591.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. Lindenberger and T. Lanne
Sex-related effects on venous compliance and capillary filtration in the lower limb
Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2007; 292(2): R852 - R859.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Epidemiol. Biomarkers Prev.Home page
C. Sweeney, M. A. Murtaugh, K. B. Baumgartner, T. Byers, A. R. Giuliano, J. S. Herrick, R. Wolff, B. J. Caan, and M. L. Slattery
Insulin-Like Growth Factor Pathway Polymorphisms Associated with Body Size in Hispanic and Non-Hispanic White Women
Cancer Epidemiol. Biomarkers Prev., July 1, 2005; 14(7): 1802 - 1809.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
K.-C. Leung, G. Johannsson, G. M. Leong, and K. K. Y. Ho
Estrogen Regulation of Growth Hormone Action
Endocr. Rev., October 1, 2004; 25(5): 693 - 721.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
S. C. Newcomer, U. A. Leuenberger, C. S. Hogeman, B. D. Handly, and D. N. Proctor
Different vasodilator responses of human arms and legs
J. Physiol., May 1, 2004; 556(3): 1001 - 1011.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online