Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 91: 2531-2536, 2001;
8750-7587/01 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (7)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wang, J.-J.
Right arrow Articles by Tyberg, J. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wang, J.-J.
Right arrow Articles by Tyberg, J. V.
Vol. 91, Issue 6, 2531-2536, December 2001

Left ventricular wave speed

Jiun-Jr Wang1, Kim H. Parker2, and John V. Tyberg1

1 Department of Medicine and Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada T2N 4N1; and 2 Physiological Flow Studies Group, Department of Bioengineering, Imperial College of Science, Technology and Medicine, London, SW7 2BY United Kingdom

Left ventricular (LV) wave speed (LVWS) was studied experimentally and confirmed in theory. Combining the definition of elastance (E) with the equations for the conservation of mass and momentum shows that LVWS is proportional to the square root of ELA, where L is long-axis length and A is the cross-sectional area, and the density of the blood. (We defined ELA = gamma , where gamma  is compressibility.) We studied nine open chest, anesthetized dogs, three of which were studied during caval constriction when LV end-diastolic pressure was <= 0 mmHg. The hearts were paced at ~90 beats/min, and LV cross-sectional area was measured by using two pairs of ultrasonic crystals; E was calculated from the LV pressure-area loop. A pulse generator was connected to the LV apex, and LVWS was measured by using two pressure transducers: one near the apex and the other near the base. Their distance was measured roentgenographically and compared with the diameter of a reference ball. LVWS ranged from ~1 m/s during diastole to ~10 m/s during systole. The slope of the log c (where c is wave speed) vs. log gamma  was 0.546, which is in agreement with theory (0.5). When gamma  <=  0, LVWS was ~1.5 m/s.

left ventricle; elastance; distensibility


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
J. A. Flewitt, T. N. Hobson, J. Wang Jr., C. R. Johnston, N. G. Shrive, I. Belenkie, K. H. Parker, and J. V. Tyberg
Wave intensity analysis of left ventricular filling: application of windkessel theory
Am J Physiol Heart Circ Physiol, June 1, 2007; 292(6): H2817 - H2823.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
Z. Wang, F. Jalali, Y.-H. Sun, J.-J. Wang, K. H. Parker, and J. V. Tyberg
Assessment of left ventricular diastolic suction in dogs using wave-intensity analysis
Am J Physiol Heart Circ Physiol, April 1, 2005; 288(4): H1641 - H1651.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
R. A. Bleasdale, K. H. Parker, and C. J. H. Jones
Chasing the wave. Unfashionable but important new concepts in arterial wave travel
Am J Physiol Heart Circ Physiol, June 1, 2003; 284(6): H1879 - H1885.
[Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
C. A. G. Kroeker, N. G. Shrive, I. Belenkie, and J. V. Tyberg
Pericardium modulates left and right ventricular stroke volumes to compensate for sudden changes in atrial volume
Am J Physiol Heart Circ Physiol, June 1, 2003; 284(6): H2247 - H2254.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online