Journal of Applied Physiology Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 91: 2442-2450, 2001;
8750-7587/01 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (10)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wilkins, P. A.
Right arrow Articles by Dobson, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wilkins, P. A.
Right arrow Articles by Dobson, A.
Vol. 91, Issue 6, 2442-2450, December 2001

Extravascular lung water in the exercising horse

P. A. Wilkins1, R. D. Gleed1, N. M. Krivitski2, and A. Dobson1

1 Departments of Physiology and Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca 14853; and 2 Transonic Systems Inc., Ithaca, New York 14850

Seven standardbred horses were exercised on a treadmill at speeds (~12 m/s) producing maximal heart rate, hypoxemia, and a mean pulmonary arterial pressure of ~75 mmHg. Extravascular lung water was measured by using transients in temperature and electrical impedance of the blood caused by a bolus injection of cold saline solution. Lung water was ~3 ml/kg body wt when standing but did not increase significantly with exertion. We conclude that any increase in fluid extravasation from the pulmonary hypertension accumulates in the lung at a level that is less than that detectable by this method. At maximal exertion, the volume of blood measured between the jugular vein and the carotid artery increased by ~8 ml/kg, and the actively circulating component of the systemic blood volume increased by ~17 ml/kg with respect to corresponding values obtained when walking before exertion. These volume increases, reflecting recruitment and dilatation of capillaries, increase the area for respiratory gas exchange and offset the reduced transit times that would otherwise be imposed by the approximately eightfold increase in cardiac output at maximal exertion.

central blood volume; actively circulating blood volume; double-indicator dilution; blood impedance; temperature


This article has been cited by other articles:


Home page
 J. Physiol.Home page
M. Vengust, H. Staempfli, L. Viel, and G. Heigenhauser
Transvascular fluid flux from the pulmonary vasculature at rest and during exercise in horses
J. Physiol., January 15, 2006; 570(2): 397 - 405.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. Manohar and T. E. Goetz
Intrapulmonary arteriovenous shunts of >15 {micro}m in diameter probably do not contribute to arterial hypoxemia in maximally exercising Thoroughbred horses
J Appl Physiol, July 1, 2005; 99(1): 224 - 229.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
P. D. Wagner, P. Wilkins, R. Gleed, A. Dobson, and N. Krivitski
Exercise, extravascular lung water, and gas exchange
J Appl Physiol, May 1, 2002; 92(5): 2224 - 2225.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online