Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 91: 2351-2358, 2001;
8750-7587/01 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (12)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gallagher, K. M.
Right arrow Articles by Raven, P. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gallagher, K. M.
Right arrow Articles by Raven, P. B.
Vol. 91, Issue 5, 2351-2358, November 2001

Increases in intramuscular pressure raise arterial blood pressure during dynamic exercise

K. M. Gallagher, P. J. Fadel, S. A. Smith, K. H. Norton, R. G. Querry, A. Olivencia-Yurvati, and P. B. Raven

Department of Integrative Physiology and the Cardiovascular Research Institute, University of North Texas Health Science Center, Fort Worth, Texas 76107-2609

This investigation was designed to determine the role of intramuscular pressure-sensitive mechanoreceptors and chemically sensitive metaboreceptors in affecting the blood pressure response to dynamic exercise in humans. Sixteen subjects performed incremental (20 W/min) cycle exercise to fatigue under four conditions: control, exercise with thigh cuff occlusion of 90 Torr (Cuff occlusion), exercise with lower body positive pressure (LBPP) of 45 Torr, and a combination of thigh cuff occlusion and LBPP (combination). Indexes of central command (heart rate, oxygen uptake, ratings of perceived exertion, and electromyographic activity), cardiac output, stroke volume, and total peripheral resistance were not significantly different between the four conditions. Mechanical stimulation during LBPP and combination conditions resulted in significant elevations in intramuscular pressure and mean arterial pressure from control at rest and throughout the incremental exercise protocol (P < 0.05). Conversely, there existed no significant changes in mean arterial pressure when the metaboreflex was stimulated by cuff occlusion. These findings suggest that under normal conditions the mechanoreflex is tonically active and is the primary mediator of exercise pressor reflex-induced alterations in arterial blood pressure during submaximal dynamic exercise in humans.

mechanoreceptors; metaboreceptors; exercise pressor reflex


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
J. P. Fisher, C. N. Young, and P. J. Fadel
Effect of muscle metaboreflex activation on carotid-cardiac baroreflex function in humans
Am J Physiol Heart Circ Physiol, May 1, 2008; 294(5): H2296 - H2304.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
P. A. Gwirtz, J. Dickey, D. Vick, M. A. Williams, and B. Foresman
Viscerosomatic interaction induced by myocardial ischemia in conscious dogs
J Appl Physiol, August 1, 2007; 103(2): 511 - 517.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
S. Ogoh, J. P. Fisher, P. J. Fadel, and P. B. Raven
Increases in central blood volume modulate carotid baroreflex resetting during dynamic exercise in humans
J. Physiol., May 15, 2007; 581(1): 405 - 418.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. M. Goodman, M. R. Freeman, and L. S. Goodman
Left ventricular function during arm exercise: influence of leg cycling and lower body positive pressure
J Appl Physiol, March 1, 2007; 102(3): 904 - 912.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S. Ogoh, R. M. Brothers, Q. Barnes, W. L. Eubank, M. N. Hawkins, S. Purkayastha, A. O-Yurvati, and P. B. Raven
Effects of changes in central blood volume on carotid-vasomotor baroreflex sensitivity at rest and during exercise
J Appl Physiol, July 1, 2006; 101(1): 68 - 75.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. K. Stickland, R. C. Welsh, M. J. Haykowsky, S. R. Petersen, W. D. Anderson, D. A. Taylor, M. Bouffard, and R. L. Jones
Effect of acute increases in pulmonary vascular pressures on exercise pulmonary gas exchange
J Appl Physiol, June 1, 2006; 100(6): 1910 - 1917.
[Abstract] [Full Text] [PDF]

Home page
 Exp PhysiolHome page
S. A Smith, J. H Mitchell, and M. G Garry
The mammalian exercise pressor reflex in health and disease
Exp Physiol, January 1, 2006; 91(1): 89 - 102.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
G. Sjogaard, B. R. Jensen, A. R. Hargens, and K. Sogaard
Intramuscular pressure and EMG relate during static contractions but dissociate with movement and fatigue
J Appl Physiol, April 1, 2004; 96(4): 1522 - 1529.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
K. Yamamoto, T. Kawada, A. Kamiya, H. Takaki, T. Miyamoto, M. Sugimachi, and K. Sunagawa
Muscle mechanoreflex induces the pressor response by resetting the arterial baroreflex neural arc
Am J Physiol Heart Circ Physiol, April 1, 2004; 286(4): H1382 - H1388.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
P. Haouzi, B. Chenuel, and A. Huszczuk
Sensing vascular distension in skeletal muscle by slow conducting afferent fibers: neurophysiological basis and implication for respiratory control
J Appl Physiol, February 1, 2004; 96(2): 407 - 418.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online