Journal of Applied Physiology Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 90: 2070-2074, 2001;
8750-7587/01 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (22)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Trappe, T. A.
Right arrow Articles by Carrithers, J. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Trappe, T. A.
Right arrow Articles by Carrithers, J. A.
Vol. 90, Issue 6, 2070-2074, June 2001

Muscle-specific atrophy of the quadriceps femoris with aging

T. A. Trappe1, D. M. Lindquist2, and J. A. Carrithers1

1 Nutrition, Metabolism, and Exercise Laboratory, Donald W. Reynolds Department of Geriatrics, and 2 Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205

We examined the size of the four muscles of the quadriceps femoris in young and old men and women to assess whether the vastus lateralis is an appropriate surrogate for the quadriceps femoris in human studies of aging skeletal muscle. Ten young (24 ± 2 yr) and ten old (79 ± 7 yr) sedentary individuals underwent magnetic resonance imaging of the quadriceps femoris after 60 min of supine rest. Volume (cm3) and average cross-sectional area (CSA, cm2) of the rectus femoris (RF), vastus lateralis (VL), vastus intermedius (VI), vastus medialis (VM), and the total quadriceps femoris were decreased (P < 0.05) in older compared with younger women and men. However, percentage of the total quadriceps femoris taken up by each muscle was similar (P > 0.05) between young and old (RF: 10 ± 0.3 vs. 11 ± 0.4; VL: 33 ± 1 vs. 33 ± 1; VI: 31 ± 1 vs. 31 ± 0.4; VM: 26 ± 1 vs. 25 ± 1%). These results suggest that each of the four muscles of the quadriceps femoris atrophy similarly in aging men and women. Our data support the use of vastus lateralis tissue to represent the quadriceps femoris muscle in aging research.

magnetic resonance imaging; rectus femoris; vastus lateralis; vastus intermedius; vastus medialis


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
J. M. Haus, J. A. Carrithers, S. W. Trappe, and T. A. Trappe
Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle
J Appl Physiol, December 1, 2007; 103(6): 2068 - 2076.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
J. M. Haus, J. A. Carrithers, C. C. Carroll, P. A. Tesch, and T. A. Trappe
Contractile and connective tissue protein content of human skeletal muscle: effects of 35 and 90 days of simulated microgravity and exercise countermeasures
Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2007; 293(4): R1722 - R1727.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
R. D. Kooistra, C. J. de Ruiter, and A. de Haan
Muscle activation and blood flow do not explain the muscle length-dependent variation in quadriceps isometric endurance
J Appl Physiol, March 1, 2005; 98(3): 810 - 816.
[Abstract] [Full Text] [PDF]

Home page
 Mult SclerHome page
L J White, S C McCoy, V Castellano, G Gutierrez, J E Stevens, G A Walter, and K Vandenborne
Resistance training improves strength and functional capacity in persons with multiple sclerosis
Multiple Sclerosis, December 1, 2004; 10(6): 668 - 674.
[Abstract] [PDF]

Home page
 J. Appl. Physiol.Home page
L. Glover, J. J. A. Heffron, and K. Ohlendieck
Increased sensitivity of the ryanodine receptor to halothane-induced oligomerization in malignant hyperthermia-susceptible human skeletal muscle
J Appl Physiol, January 1, 2004; 96(1): 11 - 18.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online