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J Appl Physiol 9: 375-379, 1956;
8750-7587/56 $5.00
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Oxygen Cost of Hyperventilation

Colin B. McKerrow 1 and Arthur B. Otis 1

1 From the Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland

A method for measuring the oxygen cost of hyperventilation is described and evaluated. The cost of maximal voluntary ventilation obtained by this method in studies of five normal men ranged from 2.13 to 0.71 l/min. The cost per unit of ventilation increased with increasing ventilation. In two subjects with obstructive pulmonary disease the cost per unit of ventilation was much higher than in the normal subjects.

Note:
with the technical assistance of Catherine Howard and Richard Bartlett.

Submitted on April 12, 1956




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