Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


J Appl Physiol 89: 1868-1878, 2000;
8750-7587/00 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (47)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Boushel, R.
Right arrow Articles by Kjær, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Boushel, R.
Right arrow Articles by Kjær, M.
Vol. 89, Issue 5, 1868-1878, November 2000

Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green

Robert Boushel1, Henning Langberg1, Jens Olesen1, Markus Nowak1, Lene Simonsen2, Jens Bülow2, and Michael Kjær1

1 Sports Medicine Research Unit and 2 Department of Clinical Physiology, Copenhagen Muscle Research Centre, Bispebjerg Hospital, Copenhagen, Denmark

Using near-infrared spectroscopy (NIRS) and the tracer indocyanine green (ICG), we quantified blood flow in calf muscle and around the Achilles tendon during plantar flexion (1-9 W). For comparison, blood flow in calf muscle was determined by dye dilution in combination with magnetic resonance imaging measures of muscle volume, and, for the peritendon region, blood flow was measured by 133Xe washout. From rest to a peak load of 9 W, NIRS-ICG blood flow in calf muscle increased from 2.4 ± 0.2 to 74 ± 5 ml · 100 ml tissue-1 · min-1, similar to that measured by reverse dye (77 ± 6 ml · 100 ml tissue-1 · min-1). Achilles peritendon blood flow measured by NIRS-ICG rose with exercise from 2.2 ± 0.5 to 15.1 ± 0.2 ml · 100 ml-1 · min-1, which was similar to that determined by 133Xe washout (2.0 ± 0.6 to 14.6 ± 0.3 ml · 100 ml tissue-1 · min-1). This is the first study using NIRS and ICG to quantify regional tissue blood flow during exercise in humans. Due to its high spatial and temporal resolution, the technique may be useful for determining regional blood flow distribution and regulation during exercise in humans.

microvascular perfusion; spectrophotometry muscle; tendon


This article has been cited by other articles:


Home page
J. Appl. Physiol.Home page
W. M. Kuebler
How NIR is the future in blood flow monitoring?
J Appl Physiol, April 1, 2008; 104(4): 905 - 906.
[Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
J. A. Guenette, I. Vogiatzis, S. Zakynthinos, D. Athanasopoulos, M. Koskolou, S. Golemati, M. Vasilopoulou, H. E. Wagner, C. Roussos, P. D. Wagner, et al.
Human respiratory muscle blood flow measured by near-infrared spectroscopy and indocyanine green
J Appl Physiol, April 1, 2008; 104(4): 1202 - 1210.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
K. K. Kalliokoski, H. Langberg, A. K. Ryberg, C. Scheede-Bergdahl, S. Doessing, A. Kjaer, M. Kjaer, and R. Boushel
Nitric oxide and prostaglandins influence local skeletal muscle blood flow during exercise in humans: coupling between local substrate uptake and blood flow
Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2006; 291(3): R803 - R809.
[Abstract] [Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
J. Bojsen-Moller, K. K. Kalliokoski, M. Seppanen, M. Kjaer, and S. P. Magnusson
Low-intensity tensile loading increases intratendinous glucose uptake in the Achilles tendon
J Appl Physiol, July 1, 2006; 101(1): 196 - 201.
[Abstract] [Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
S. L. Davis, P. J. Fadel, J. Cui, G. D. Thomas, and C. G. Crandall
Skin blood flow influences near-infrared spectroscopy-derived measurements of tissue oxygenation during heat stress
J Appl Physiol, January 1, 2006; 100(1): 221 - 224.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
G. Pichler, B. Urlesberger, P. Jirak, H. Zotter, E. Reiterer, W. Muller, and M. Borkenstein
Reduced Forearm Blood Flow in Children and Adolescents With Type 1 Diabetes (Measured by Near-Infrared Spectroscopy)
Diabetes Care, August 1, 2004; 27(8): 1942 - 1946.
[Abstract] [Full Text] [PDF]


Home page
Physiol. Rev.Home page
M. KJAeR
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
Physiol Rev, April 1, 2004; 84(2): 649 - 698.
[Abstract] [Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
P. J. Fadel, D. M. Keller, H. Watanabe, P. B. Raven, and G. D. Thomas
Noninvasive assessment of sympathetic vasoconstriction in human and rodent skeletal muscle using near-infrared spectroscopy and Doppler ultrasound
J Appl Physiol, April 1, 2004; 96(4): 1323 - 1330.
[Abstract] [Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
K. K. Kalliokoski, M. S. Laaksonen, T. O. Takala, J. Knuuti, and P. Nuutila
Muscle oxygen extraction and perfusion heterogeneity during continuous and intermittent static exercise
J Appl Physiol, March 1, 2003; 94(3): 953 - 958.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online