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1 Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261; 2 Department of Radiology, and 5 Prevention Sciences Group, University of California, San Francisco 94105; 4 Department of Kinesiology, San Francisco State University, San Francisco, California 94132; 3 Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892; 6 Department of Preventive Medicine, University of Tennessee, Memphis, Tennessee 38105; and 7 Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona 85721
The accuracy of total body fat mass and leg fat mass
measurements by fan-beam dual-energy X-ray absorptiometry
(DEXA) was assessed in 60 healthy elderly subjects (aged
70-79 yr). Total fat and leg fat mass at four leg regions
(total leg, thigh, midthigh, and calf) were measured with the QDR 4500A
(Hologic, Waltham, MA). The four-compartment model and multislice
computed tomography scans were selected as criterion methods for total
fat and leg fat mass, respectively. Total fat mass from DEXA was
positively associated with fat mass from the four-compartment model
with a standard error of the estimate ranging from 1.4 to 1.6 kg. DEXA fan-beam tended to overestimate fat mass for total leg and total thigh
fat mass, whereas only marginal differences in fat mass measurements at
the midthigh and calf were demonstrated (
0.08 kg, P < 0.0005). Although there were significant differences between DEXA
fan beam and the criterion methods, these differences were of small
magnitude, suggesting that DEXA is an accurate method for measurement
of fat mass for the elderly.
body composition; dual-energy X-ray absorptiometry; fan beam; computed tomography
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