Journal of Applied Physiology Ad Instruments
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 88: 2123-2130, 2000;
8750-7587/00 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (9)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fuller, D. D.
Right arrow Articles by Fregosi, R. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fuller, D. D.
Right arrow Articles by Fregosi, R. F.
Vol. 88, Issue 6, 2123-2130, June 2000

Fatiguing contractions of tongue protrudor and retractor muscles: influence of systemic hypoxia

David D. Fuller and Ralph F. Fregosi

Respiratory Physiology Laboratory, Department of Physiology, University of Arizona, Tucson, Arizona 85719

The influence of systemic hypoxia on the endurance performance of tongue protrudor and retractor muscles was examined in anesthetized, ventilated rats. Tongue protrudor (genioglossus) or retractor (hyoglossus and styloglossus) muscles were activated via medial or lateral XII nerve branch stimulation (0.1-ms pulse; 40 Hz; 330-ms trains; 1 train/s). Maximal evoked potentials (M waves) of genioglossus and hyoglossus were monitored with electromyography. Fatigue tests were performed under normoxic and hypoxic (arterial PO2 = 50 ± 1 Torr) conditions in separate animals. The fatigue index (FI; %initial force) after 5 min of normoxic stimulation was 85 ± 6 and 79 ± 7% for tongue protrudor and retractor muscles, respectively; these values were significantly lower during hypoxia (protrudor FI = 52 ± 10, retractor FI = 18 ± 6%; P < 0.05). Protrudor and retractor muscle M-wave amplitude declined over the course of the hypoxic fatigue test but did not change during normoxia (P < 0.05). We conclude that hypoxia attenuates tongue protrudor and retractor muscle endurance performance; potential mechanisms include neuromuscular transmission failure and/or diminished sarcolemmal excitability.

fatigue; genioglossus; hyoglossus; stylogossus; M wave


This article has been cited by other articles:


Home page
 JSLHRHome page
N. P. Connor, F. Ota, H. Nagai, J. A. Russell, and G. Leverson
Differences in Age-Related Alterations in Muscle Contraction Properties in Rat Tongue and Hindlimb
J Speech Lang Hear Res, August 1, 2008; 51(4): 818 - 827.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
J. John, E. F. Bailey, and R. F. Fregosi
Respiratory-related Discharge of Genioglossus Muscle Motor Units
Am. J. Respir. Crit. Care Med., November 15, 2005; 172(10): 1331 - 1337.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
E. F. Bailey, P. L. Janssen, and R. F. Fregosi
PO2-dependent Changes in Intrinsic and Extrinsic Tongue Muscle Activities in the Rat
Am. J. Respir. Crit. Care Med., June 15, 2005; 171(12): 1403 - 1407.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
E.-K. Pae, J. Wu, D. Nguyen, R. Monti, and R. M. Harper
Geniohyoid muscle properties and myosin heavy chain composition are altered after short-term intermittent hypoxic exposure
J Appl Physiol, March 1, 2005; 98(3): 889 - 894.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
E. F. Bailey and R. F. Fregosi
Coordination of intrinsic and extrinsic tongue muscles during spontaneous breathing in the rat
J Appl Physiol, February 1, 2004; 96(2): 440 - 449.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
T. CLAUSEN
Na+-K+ Pump Regulation and Skeletal Muscle Contractility
Physiol Rev, October 1, 2003; 83(4): 1269 - 1324.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online