| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Magnetic Resonance Unit, Department of Radiology, University of California, San Francisco, California 94121
To examine the influences of age, gender, and habitual
physical activity level on human skeletal muscle composition, we
developed a relatively simple magnetic resonance imaging method for the quantitation of leg anterior compartment contractile and noncontractile content. We studied 23 young (11 women and 12 men, 26-44 yr old) and 21 older (10 women and 11 men, 65-83 yr old) healthy adults. Analysis was by two-factor (age, gender) ANOVA. Physical activity, quantitated by three-dimensional accelerometer worn about the waist for
1 wk, was not different between groups. Men had larger contractile and
noncontractile cross-sectional areas
(cm2) than women, with no gender
effect on percent noncontractile area. Young subjects had larger
contractile areas and smaller absolute
(cm2) and relative (percent
total) noncontractile areas than older subjects. There was a
significant linear relationship between physical activity and percent
noncontractile area in older (r = 
0.68, P = 0.002) but not young
subjects. These data demonstrate a more than twofold increase in the
noncontractile content of locomotor muscles in older adults and provide
novel support for physical activity as a modulator of this age-related
change in muscle composition.
muscle function; aging; physical activity; fat; gender
This article has been cited by other articles:
|
|
 |
|
  N. I. Tanaka, M. Miyatani, Y. Masuo, T. Fukunaga, and H. Kanehisa Applicability of a segmental bioelectrical impedance analysis for predicting the whole body skeletal muscle volume J Appl Physiol, November 1, 2007; 103(5): 1688 - 1695. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. de Boer, C. N. Maganaris, O. R. Seynnes, M. J. Rennie, and M. V. Narici Time course of muscular, neural and tendinous adaptations to 23 day unilateral lower-limb suspension in young men J. Physiol., September 15, 2007; 583(3): 1079 - 1091. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. McNeil, A. A. Vandervoort, and C. L. Rice Peripheral impairments cause a progressive age-related loss of strength and velocity-dependent power in the dorsiflexors J Appl Physiol, May 1, 2007; 102(5): 1962 - 1968. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. J. Galban, S. Maderwald, F. Stock, and M. E. Ladd Age-Related Changes in Skeletal Muscle as Detected by Diffusion Tensor Magnetic Resonance Imaging J. Gerontol. A Biol. Sci. Med. Sci., April 1, 2007; 62(4): 453 - 458. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. M Manini, B. C Clark, M. A Nalls, B. H Goodpaster, L. L Ploutz-Snyder, and T. B Harris Reduced physical activity increases intermuscular adipose tissue in healthy young adults Am. J. Clinical Nutrition, February 1, 2007; 85(2): 377 - 384. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. L. Onambele, M. V. Narici, and C. N. Maganaris Calf muscle-tendon properties and postural balance in old age J Appl Physiol, June 1, 2006; 100(6): 2048 - 2056. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. D. Reeves, M. V. Narici, and C. N. Maganaris Myotendinous plasticity to ageing and resistance exercise in humans Exp Physiol, May 1, 2006; 91(3): 483 - 498. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. Hunter, A. Critchlow, and R. M. Enoka Muscle endurance is greater for old men compared with strength-matched young men J Appl Physiol, September 1, 2005; 99(3): 890 - 897. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. I. Morse, J. M. Thom, N. D. Reeves, K. M. Birch, and M. V. Narici In vivo physiological cross-sectional area and specific force are reduced in the gastrocnemius of elderly men J Appl Physiol, September 1, 2005; 99(3): 1050 - 1055. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Simoneau, A. Martin, and J. Van Hoecke Muscular Performances at the Ankle Joint in Young and Elderly Men J. Gerontol. A Biol. Sci. Med. Sci., April 1, 2005; 60(4): 439 - 447. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. Hunter, A. Critchlow, and R. M. Enoka Influence of aging on sex differences in muscle fatigability J Appl Physiol, November 1, 2004; 97(5): 1723 - 1732. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. K. Barry and R. G. Carson The Consequences of Resistance Training for Movement Control in Older Adults J. Gerontol. A Biol. Sci. Med. Sci., July 1, 2004; 59(7): M730 - M754. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. H Goodpaster, V A. Stenger, F. Boada, T. McKolanis, D. Davis, R. Ross, and D. E Kelley Skeletal muscle lipid concentration quantified by magnetic resonance imaging Am. J. Clinical Nutrition, May 1, 2004; 79(5): 748 - 754. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. R. Lanza, T. F. Towse, G. E. Caldwell, D. M. Wigmore, and J. A. Kent-Braun Effects of age on human muscle torque, velocity, and power in two muscle groups J Appl Physiol, December 1, 2003; 95(6): 2361 - 2369. [Abstract] [Full Text]
|
|
|
|
|
|
T. J. Doherty Invited Review: Aging and sarcopenia J Appl Physiol, October 1, 2003; 95(4): 1717 - 1727. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T Abe, C F Kearns, and T Fukunaga Sex differences in whole body skeletal muscle mass measured by magnetic resonance imaging and its distribution in young Japanese adults Br. J. Sports Med., October 1, 2003; 37(5): 436 - 440. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. N Williams, M. J Higgins, and M. D Lewek Aging Skeletal Muscle: Physiologic Changes and the Effects of Training Physical Therapy, January 1, 2002; 82(1): 62 - 68. [Full Text] [PDF]
|
|
|
|
|
|
M. Miyatani, H. Kanehisa, Y. Masuo, M. Ito, and T. Fukunaga Validity of estimating limb muscle volume by bioelectrical impedance J Appl Physiol, July 1, 2001; 91(1): 386 - 394. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. W. Reid, J. M. Foley, R. C. Jayaraman, B. M. Prior, and R. A. Meyer Effect of aerobic capacity on the T2 increase in exercised skeletal muscle J Appl Physiol, March 1, 2001; 90(3): 897 - 902. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Kent-Braun and A. V. Ng Skeletal muscle oxidative capacity in young and older women and men J Appl Physiol, September 1, 2000; 89(3): 1072 - 1078. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
