| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Departments of 1 Physical Therapy and 2 Radiology, and the 3 Moss Heart Center, University of Texas Southwestern Medical Center, Dallas, Texas 75235-8876
The purpose of
this investigation was to determine whether there were differences in
the magnitude of insular cortex activation across varying intensities
of static and dynamic exercise. Eighteen healthy
volunteers were studied: eight during two intensities of leg cycling
and ten at different time periods during sustained static handgrip at
25% maximal voluntary contraction or postexercise cuff occlusion.
Heart rate, blood pressure (BP), perceived exertion, and regional
cerebral blood flow (rCBF) distribution data were collected. There were
significantly greater increases in insular rCBF during lower (6.3 ± 1.7%; P < 0.05) and higher (13.3 ± 3.8%; P < 0.05) intensity
cycling and across time during static handgrip (change from rest for
right insula at 2-3 min, 3.8 ± 1.1%,
P < 0.05; and at 4-5 min, 8.6 ± 2.8%, P < 0.05).
Insular rCBF was decreased during postexercise cuff occlusion
(
5.5 ± 1.2%; P < 0.05)
with BP sustained at exercise levels. Right insular rCBF data, but not
left, were significantly related, with individual BP changes
(r2 = 0.80;
P < 0.001) and with
ratings of perceived exertion
(r2 = 0.79;
P < 0.01) during exercise.
These results suggest that the magnitude of insular activation varies
with the intensity of exercise, which may be further related to the
level of perceived effort or central command.
human; brain; single-photon emission-computed tomography; magnetic resonance imaging; autonomic nervous system
This article has been cited by other articles:
|
|
 |
|
  R. J. Fox, R. W. McColl, J.-C. Lee, T. Frohman, K. Sakaie, and E. Frohman A Preliminary Validation Study of Diffusion Tensor Imaging as a Measure of Functional Brain Injury Arch Neurol, September 1, 2008; 65(9): 1179 - 1184. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. L. Green and D. J. Paterson Identification of neurocircuitry controlling cardiovascular function in humans using functional neurosurgery: implications for exercise control Exp Physiol, September 1, 2008; 93(9): 1022 - 1028. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W Williamson, P. J Fadel, and J. H Mitchell New insights into central cardiovascular control during exercise in humans: a central command update Exp Physiol, January 1, 2006; 91(1): 51 - 58. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. von Leupoldt and B. Dahme Cortical Substrates for the Perception of Dyspnea Chest, July 1, 2005; 128(1): 345 - 354. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A St Clair Gibson and T D Noakes Evidence for complex system integration and dynamic neural regulation of skeletal muscle recruitment during exercise in humans Br. J. Sports Med., December 1, 2004; 38(6): 797 - 806. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. K. Dalsgaard, S. Volianitis, C. C. Yoshiga, E. A. Dawson, and N. H. Secher Cerebral metabolism during upper and lower body exercise J Appl Physiol, November 1, 2004; 97(5): 1733 - 1739. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. D. Rosen, K. Murphy, A. P. Leff, V. Cunningham, R. J.S. Wise, L. Adams, A. J.S. Coats, and P. G. Camici Is central nervous system processing altered in patients with heart failure? Eur. Heart J., June 1, 2004; 25(11): 952 - 962. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Williamson, R. McColl, and D. Mathews Changes in regional cerebral blood flow distribution during postexercise hypotension in humans J Appl Physiol, February 1, 2004; 96(2): 719 - 724. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. K. Dalsgaard, B. Quistorff, E. R. Danielsen, C. Selmer, T. Vogelsang, and N. H. Secher A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain J. Physiol., January 15, 2004; 554(2): 571 - 578. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Nybo, B. Nielsen, E. Blomstrand, K. Moller, and N. Secher Neurohumoral responses during prolonged exercise in humans J Appl Physiol, September 1, 2003; 95(3): 1125 - 1131. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Brys, C. M. Brown, H. Marthol, R. Franta, and M. J. Hilz Dynamic cerebral autoregulation remains stable during physical challenge in healthy persons Am J Physiol Heart Circ Physiol, August 7, 2003; 285(3): H1048 - H1054. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Williamson, R. McColl, and D. Mathews Evidence for central command activation of the human insular cortex during exercise J Appl Physiol, May 1, 2003; 94(5): 1726 - 1734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Williamson, R. McColl, D. Mathews, J. H. Mitchell, P. B. Raven, and W. P. Morgan Brain activation by central command during actual and imagined handgrip under hypnosis J Appl Physiol, March 1, 2002; 92(3): 1317 - 1324. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Williamson, R. McColl, D. Mathews, J. H. Mitchell, P. B. Raven, and W. P. Morgan Hypnotic manipulation of effort sense during dynamic exercise: cardiovascular responses and brain activation J Appl Physiol, April 1, 2001; 90(4): 1392 - 1399. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. PEIFFER, J.-B. POLINE, L. THIVARD, M. AUBIER, and Y. SAMSON Neural Substrates for the Perception of Acutely Induced Dyspnea Am. J. Respir. Crit. Care Med., March 15, 2001; 163(4): 951 - 957. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
