Journal of Applied Physiology Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 87: 683-688, 1999;
8750-7587/99 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Binzoni, T.
Right arrow Articles by Cerretelli, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Binzoni, T.
Right arrow Articles by Cerretelli, P.
Vol. 87, Issue 2, 683-688, August 1999

Muscle O2 consumption by NIRS: a theoretical model

T. Binzoni1, W. Colier2, E. Hiltbrand1, L. Hoofd2, and P. Cerretelli1

1 Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland; and 2 Department of Physiology, Faculty of Medical Sciences, University of Nijmegen, 6500 HB Nijmegen, The Netherlands

In the past, the measurement of O2 consumption (O2) by the muscle could be carried out noninvasively by near-infrared spectroscopy from oxyhemoglobin and/or deoxyhemoglobin measurements only at rest or during steady isometric contractions. In the present study, a mathematical model is developed allowing calculation, together with steady-state levels of O2, of the kinetics of O2 readjustment in the muscle from the onset of ischemic but aerobic constant-load isotonic exercises. The model, which is based on the known sequence of exoergonic metabolic pathways involved in muscle energetics, allows simultaneous fitting of batched data obtained during exercises performed at different workloads. A Monte Carlo simulation has been carried out to test the quality of the model and to define the most appropriate experimental approach to obtain the best results. The use of a series of experimental protocols obtained at different levels of mechanical power, rather than repetitions of the same load, appears to be the most suitable procedure.

human skeletal muscle; oxygen consumption kinetics; near-infrared spectroscopy


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
M. Burnley, J. H. Doust, D. Ball, and A. M. Jones
Effects of prior heavy exercise on VO2 kinetics during heavy exercise are related to changes in muscle activity
J Appl Physiol, July 1, 2002; 93(1): 167 - 174.
[Abstract] [Full Text] [PDF]

Home page
 Integr. Comp. Biol.Home page
P. Cerretelli and B. Grassi
Gas Exchange, MRS and NIRS Assessment of Metabolic Transients in Skeletal Muscle
Integr. Comp. Biol., April 1, 2001; 41(2): 229 - 246.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online