Journal of Applied Physiology
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J Appl Physiol 86: 647-650, 1999;
8750-7587/99 $5.00
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Vol. 86, Issue 2, 647-650, February 1999

Infrared CO2 analyzer error: an effect of background gas (N2 and O2)

R. Arieli, O. Ertracht, and Y. Daskalovic

Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa 31080, Israel

Three infrared CO2 analyzers were tested for the effect of background gases: the Ametek CD-3A (Ametek, Thermox Instruments Division, Pittsburgh, PA), the Dräger Multiwarn P CO2 (Dräger, Lübeck, Germany), and the Servomex 1440 (Servomex, Crowborough, East Sussex, UK). Various CO2 concentrations were prepared with Wösthoff precision pumps (H. Wösthoff, Bochum, Germany). Calibration with a different background gas (O2 or N2) caused a similar but systematic error in the CO2 readings of all three analyzers. When the CO2 analyzers were calibrated with N2 as the background gas, the CO2 reading in an O2-enriched atmosphere was 8% lower than the true value. Conversely, calibration with O2 as the background gas resulted in a 10% overestimation of CO2 levels when N2 was the background gas. This error may be important in a few fields of respiratory physiology.

carbon dioxide calibration; hyperoxia; alveolar-arterial difference





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