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Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa 31080, Israel
Three
infrared CO2 analyzers were tested
for the effect of background gases: the Ametek CD-3A (Ametek, Thermox
Instruments Division, Pittsburgh, PA), the Dräger Multiwarn P
CO2 (Dräger, Lübeck,
Germany), and the Servomex 1440 (Servomex, Crowborough, East Sussex,
UK). Various CO2 concentrations
were prepared with Wösthoff precision pumps (H. Wösthoff,
Bochum, Germany). Calibration with a different background gas
(O2 or
N2) caused a similar but systematic error in the CO2
readings of all three analyzers. When the
CO2 analyzers were calibrated with
N2 as the background gas, the
CO2 reading in an
O2-enriched atmosphere was 8%
lower than the true value. Conversely, calibration with
O2 as the background gas resulted
in a 10% overestimation of CO2
levels when N2 was the background
gas. This error may be important in a few fields of respiratory physiology.
carbon dioxide calibration; hyperoxia; alveolar-arterial difference
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