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Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
We tested the hypothesis that the slower
increase in alveolar oxygen uptake
(
O2) at the onset of
supine, compared with upright, exercise would be accompanied by a
slower rate of increase in leg blood flow (LBF). Seven healthy subjects
performed transitions from rest to 40-W knee extension exercise in the
upright and supine positions. LBF was measured continuously with pulsed
and echo Doppler methods, and
O2 was measured breath by
breath at the mouth. At rest, a smaller diameter of the
femoral artery in the supine position
(P < 0.05) was compensated by a
greater mean blood flow velocity (MBV) (P < 0.05) so that LBF was not different in the two positions. At the end of
6 min of exercise, femoral artery diameter was larger in the upright
position and there were no differences in
O2, MBV, or LBF between
upright and supine positions. The rates of increase of
O2 and LBF in the
transition between rest and 40 W exercise, as evaluated by the mean
response time (time to 63% of the increase), were slower in the supine
[O2 = 39.7 ± 3.8 (SE) s, LBF = 27.6 ± 3.9 s] than in the upright
positions (O2 = 29.3 ± 3.0 s, LBF = 17.3 ± 4.0 s;
P < 0.05). These data support our
hypothesis that slower increases in alveolar
O2 at the onset of exercise
in the supine position are accompanied by a slower increase in LBF.
kicking exercise; Doppler velocimetry; echo Doppler; leg blood flow
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