| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Vol. 84, Issue 2, 450-453, February 1998
Autonomic and Cardiovascular Control Laboratory, Department of Exercise Science, University of Georgia, Athens, Georgia 30602
Ray, Chester A., and Keith M. Hume. Neck afferents and
muscle sympathetic activity in humans: implications for the vestibulosympathetic reflex. J. Appl.
Physiol. 84(2): 450-453, 1998.
We have shown
previously that head-down neck flexion (HDNF) in humans elicits
increases in muscle sympathetic nerve activity (MSNA). The purpose of
this study was to determine the effect of neck muscle afferents on
MSNA. We studied this question by measuring MSNA before and after head
rotation that would activate neck muscle afferents but not the
vestibular system (i.e., no stimulation of the otolith organs or
semicircular canals). After a 3-min baseline period with the head in
the normal erect position, subjects rotated their head to the side
(~90°) and maintained this position for 3 min. Head rotation was
performed by the subjects in both the prone
(n = 5) and sitting
(n = 6) positions. Head rotation did not elicit changes in MSNA. Average MSNA, expressed as
burst frequency and total activity, was 13 ± 1 and 13 ± 1 bursts/min and 146 ± 34 and 132 ± 27 units/min during baseline
and head rotation, respectively. There were no significant changes in
calf blood flow (2.6 ± 0.3 to 2.5 ± 0.3 ml · 100 ml
1 · min1;
n = 8) and calf vascular resistance
(39 ± 4 to 41 ± 4 units; n = 8). Heart rate (64 ± 3 to 66 ± 3 beats/min;
P = 0.058) and mean arterial pressure
(90 ± 3 to 93 ± 3; P < 0.05)
increased slightly during head rotation. Additional neck flexion
studies were performed with subjects lying on their side
(n = 5). MSNA, heart rate, and mean
arterial pressure were unchanged during this maneuver, which also does
not engage the vestibular system. HDNF was tested in 9 of the 13 subjects. MSNA was significantly increased by 79 ± 12% (P < 0.001) during HDNF. These
findings indicate that neck afferents activated by horizontal neck
rotation or flexion in the absence of significant force development do
not elicit changes in MSNA. These findings support the concept that
HDNF increases MSNA by the activation of the vestibular system.
autonomic nervous system; cardiovascular control; graviceptors; orthostasis; sympathetic nerve activity; neck reflexes; vascular resistance
This article has been cited by other articles:
|
|
 |
|
  J. R. Carter and C. A. Ray Sympathetic responses to vestibular activation in humans Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2008; 294(3): R681 - R688. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. Dyckman, K. D. Monahan, and C. A. Ray Effect of baroreflex loading on the responsiveness of the vestibulosympathetic reflex in humans J Appl Physiol, September 1, 2007; 103(3): 1001 - 1006. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Zhu, J. R. Jordan, S. P. G. Hardy, B. Fulcher, C. Childress, C. Varner, B. Windham, B. Jeffcoat, R. W. Rockhold, and W. Zhou Linear acceleration-evoked cardiovascular responses in awake rats J Appl Physiol, August 1, 2007; 103(2): 646 - 654. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Alkaissi, T. Ledin, L. M. Odkvist, and S. Kalman P6 acupressure increases tolerance to nauseogenic motion stimulation in women at high risk for PONV: [L'acupression en P6 augmente la tolerance a la stimulation nauseogene du mouvement chez des femmes a haut risque de NVPO] Can J Anesth, August 1, 2005; 52(7): 703 - 709. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. L. Mori, L. A. Cotter, H. E. Arendt, C. J. Olsheski, and B. J. Yates Effects of bilateral vestibular nucleus lesions on cardiovascular regulation in conscious cats J Appl Physiol, February 1, 2005; 98(2): 526 - 533. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Ray and K. D. Monahan Aging, opioid-receptor agonists and antagonists, and the vestibulosympathetic reflex in humans J Appl Physiol, May 1, 2004; 96(5): 1761 - 1766. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. H. Cooke, J. R. Carter, and T. A. Kuusela Human cerebrovascular and autonomic rhythms during vestibular activation Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2004; 286(5): R838 - R843. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. M. Gotoh, N. Fujiki, T. Matsuda, S. Gao, and H. Morita Roles of baroreflex and vestibulosympathetic reflex in controlling arterial blood pressure during gravitational stress in conscious rats Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2004; 286(1): R25 - R30. [Abstract] [Full Text]
|
|
|
|
|
|
K. D. Monahan and C. A. Ray Vestibulosympathetic reflex during orthostatic challenge in aging humans Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2002; 283(5): R1027 - R1032. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Carter, C. A. Ray, and W. H. Cooke Vestibulosympathetic reflex during mental stress J Appl Physiol, October 1, 2002; 93(4): 1260 - 1264. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Monos, M. Lorant, and E. Feher Influence of long-term experimental orthostatic body position on innervation density in extremity vessels Am J Physiol Heart Circ Physiol, October 1, 2001; 281(4): H1606 - H1612. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Cui, S. Iwase, T. Mano, N. Katayama, and S. Mori Muscle sympathetic outflow during horizontal linear acceleration in humans Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2001; 281(2): R625 - R634. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Lee, R. H. Wood, and M. A. Welsch Influence of head-down and lateral decubitus neck flexion on heart rate variability J Appl Physiol, January 1, 2001; 90(1): 127 - 132. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Ray Interaction between vestibulosympathetic and skeletal muscle reflexes on sympathetic activity in humans J Appl Physiol, January 1, 2001; 90(1): 242 - 247. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Ray Interaction of the vestibular system and baroreflexes on sympathetic nerve activity in humans Am J Physiol Heart Circ Physiol, November 1, 2000; 279(5): H2399 - H2404. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Ray Effect of gender on vestibular sympathoexcitation Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2000; 279(4): R1330 - R1333. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. A. Kerman, B. J. Yates, and R. M. McAllen Anatomic patterning in the expression of vestibulosympathetic reflexes Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2000; 279(1): R109 - R117. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Hume and C. A. Ray Sympathetic responses to head-down rotations in humans J Appl Physiol, June 1, 1999; 86(6): 1971 - 1976. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Cui, S. Iwase, T. Mano, and H. Kitazawa Responses of sympathetic outflow to skin during caloric stimulation in humans Am J Physiol Regulatory Integrative Comp Physiol, March 1, 1999; 276(3): R738 - R744. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Ray, K. M. Hume, and S. L. Steele Sympathetic nerve activity during natural stimulation of horizontal semicircular canals in humans Am J Physiol Regulatory Integrative Comp Physiol, October 1, 1998; 275(4): R1274 - R1278. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. D. Monahan, M. K. Sharpe, D. Drury, A. C. Ertl, and C. A. Ray Influence of vestibular activation on respiration in humans Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2002; 282(3): R689 - R694. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. A. Ray and K. D. Monahan Aging Attenuates the Vestibulosympathetic Reflex in Humans Circulation, February 26, 2002; 105(8): 956 - 961. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
