Journal of Applied Physiology AJP citation statistics
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 83: 2080-2085, 1997;
8750-7587/97 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wang, J.-S.
Right arrow Articles by Chen, H.-I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wang, J.-S.
Right arrow Articles by Chen, H.-I.

Vol. 83, Issue 6, 2080-2085, December 1997

Effects of chronic exercise and deconditioning on platelet function in women

Jong-Shyan Wang, Chauying J. Jen, and Hsiun-Ing Chen

Department of Physiology, National Cheng-Kung University Medical College, Tainan, Taiwan 701, Republic of China

Received 25 March 1997; accepted in final form 28 July 1997.

Wang, Jong-Shyan, Chauying J. Jen, and Hsiun-Ing Chen. Effects of chronic exercise and deconditioning on platelet function in women. J. Appl. Physiol. 83(6): 2080-2085, 1997.---To investigate the effects of chronic exercise and deconditioning on platelet function in women, 16 healthy sedentary women were divided into control and exercise groups. The exercise group cycled on an ergometer at 50% maximal oxygen consumption for 30 min/day, 5 days/wk, for two consecutive menstrual cycles and then were deconditioned for three menstrual cycles. During this period, platelet adhesiveness on a fibrinogen-coated surface, ADP-induced platelet aggregation and intracellular calcium concentration elevation, guanosine 3',5'-cyclic monophosphate (cGMP) content in platelets, and plasma nitric oxide metabolite levels were measured before and immediately after a progressive exercise test in the midfollicular phase. Our results indicated that, after exercise training, 1) resting heart rates and blood pressures were reduced, and exercise performance was improved; 2) resting platelet function was decreased, whereas plasma nitrite and nitrate levels and platelet cGMP contents were enhanced; and 3) the potentiation of platelet function by acute strenuous exercise was decreased, whereas the increases in plasma nitrite and nitrate levels and platelet cGMP contents were enhanced by acute exercise. Furthermore, deconditioning reversed these training effects. This implies that training-induced platelet functional changes in women in the midfollicular phase may be mediated by nitric oxide.

platelet adhesion; aggregation; nitric oxide; midfollicular phase; guanosine 3',5'-cyclic monophosphate

0161-7567/97 $5.00 Copyright © 1997 the American Physiological Society




This article has been cited by other articles:


Home page
 AMERICAN JOURNAL OF LIFESTYLE MEDICINEHome page
R. F. Zoeller JR
Physical Activity: Depression, Anxiety, Physical Activity, and Cardiovascular Disease: What's the Connection?
American Journal of Lifestyle Medicine, May 1, 2007; 1(3): 175 - 180.
[Abstract] [PDF]

Home page
 HeartHome page
K W Lee, A D Blann, J Ingram, K Jolly, G Y H Lip, and on behalf of the BRUM Investigators
Incremental shuttle walking is associated with activation of haemostatic and haemorheological markers in patients with coronary artery disease: the Birmingham rehabilitation uptake maximisation study (BRUM)
Heart, November 1, 2005; 91(11): 1413 - 1417.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
V. A. Cornelissen and R. H. Fagard
Effects of Endurance Training on Blood Pressure, Blood Pressure-Regulating Mechanisms, and Cardiovascular Risk Factors
Hypertension, October 1, 2005; 46(4): 667 - 675.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
J.-S. Wang, Y.-S. Li, J.-C. Chen, and Y.-W. Chen
Effects of Exercise Training and Deconditioning on Platelet Aggregation Induced by Alternating Shear Stress in Men
Arterioscler Thromb Vasc Biol, February 1, 2005; 25(2): 454 - 460.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
K. W. Lee and G. Y. H. Lip
Effects of Lifestyle on Hemostasis, Fibrinolysis, and Platelet Reactivity: A Systematic Review
Arch Intern Med, October 27, 2003; 163(19): 2368 - 2392.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
F. W. Booth, M. V. Chakravarthy, S. E. Gordon, and E. E. Spangenburg
Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy
J Appl Physiol, July 1, 2002; 93(1): 3 - 30.
[Abstract] [Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
S. P. Whelton, A. Chin, X. Xin, and J. He
Effect of Aerobic Exercise on Blood Pressure: A Meta-Analysis of Randomized, Controlled Trials
Ann Intern Med, April 2, 2002; 136(7): 493 - 503.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
H. Ikarugi, T. Taka, S. Nakajima, T. Noguchi, S. Watanabe, Y. Sasaki, S. Haga, T. Ueda, J. Seki, and J. Yamamoto
Norepinephrine, but not epinephrine, enhances platelet reactivity and coagulation after exercise in humans
J Appl Physiol, January 1, 1999; 86(1): 133 - 138.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online