Vol. 83, Issue 5, 1413-1417, 1997

Heat shock proteins and heat adaptation of the whole organism

Pope L. Moseley

Pulmonary, Allergy, and Critical Care Division, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131-5271

Moseley, Pope L. Heat shock proteins and heat adaptation of the whole organism. J. Appl. Physiol. 83(5): 1413-1417, 1997.Adaptation to heat may occur through acclimatization or thermotolerance; however, the linkage of these phenomena is poorly understood. The importance of heat shock proteins (HSPs) in thermotolerance and differences in their accumulation in organisms adapted to the heat suggest a role for HSPs in acclimatization as well. The role of HSPs in heat adaptation of the whole organism and the interrelationships among heat adaptation, endotoxin tolerance, and cytokine resistance through HSPs are reviewed.

acclimatization; thermotolerance

This article has been cited by other articles:

				A. T. Jacobs and L. J. Marnett HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins J. Biol. Chem., April 3, 2009; 284(14): 9176 - 9183. [Abstract] [Full Text] [PDF]

				A. T. Jacobs and L. J. Marnett Heat Shock Factor 1 Attenuates 4-Hydroxynonenal-mediated Apoptosis: CRITICAL ROLE FOR HEAT SHOCK PROTEIN 70 INDUCTION AND STABILIZATION OF Bcl-XL J. Biol. Chem., November 16, 2007; 282(46): 33412 - 33420. [Abstract] [Full Text] [PDF]

				P. M. Yamada, F. T. Amorim, P. Moseley, R. Robergs, and S. M. Schneider Effect of heat acclimation on heat shock protein 72 and interleukin-10 in humans J Appl Physiol, October 1, 2007; 103(4): 1196 - 1204. [Abstract] [Full Text] [PDF]

				C. I. Rodgers, K. L. Shoemaker, and R. M. Robertson Photoperiod-induced plasticity of thermosensitivity and acquired thermotolerance in Locusta migratoria J. Exp. Biol., December 1, 2006; 209(23): 4690 - 4700. [Abstract] [Full Text] [PDF]

				W. C. Lee, H. C. Wen, C. P. Chang, M. Y. Chen, and M. T. Lin Heat shock protein 72 overexpression protects against hyperthermia, circulatory shock, and cerebral ischemia during heatstroke J Appl Physiol, June 1, 2006; 100(6): 2073 - 2082. [Abstract] [Full Text] [PDF]

				S. J. Neal, S. Karunanithi, A. Best, A. K.-C. So, R. M. Tanguay, H. L. Atwood, and J. T. Westwood Thermoprotection of synaptic transmission in a Drosophila heat shock factor mutant is accompanied by increased expression of Hsp83 and DnaJ-1 Physiol Genomics, May 16, 2006; 25(3): 493 - 501. [Abstract] [Full Text] [PDF]

				L. Szalay, T. Shimizu, T. Suzuki, H.-P. Yu, M. A. Choudhry, M. G. Schwacha, L. W. Rue III, K. I. Bland, and I. H. Chaudry Estradiol improves cardiac and hepatic function after trauma-hemorrhage: role of enhanced heat shock protein expression Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2006; 290(3): R812 - R818. [Abstract] [Full Text] [PDF]

				K. Heise, S. Puntarulo, M. Nikinmaa, D. Abele, and H.-O. Portner Oxidative stress during stressful heat exposure and recovery in the North Sea eelpout Zoarces viviparus L. J. Exp. Biol., January 15, 2006; 209(2): 353 - 363. [Abstract] [Full Text] [PDF]

				A. Shabtay and Z. Arad Ectothermy and endothermy: evolutionary perspectives of thermoprotection by HSPs J. Exp. Biol., July 15, 2005; 208(14): 2773 - 2781. [Abstract] [Full Text] [PDF]

				M. Horowitz, L. Eli-Berchoer, I. Wapinski, N. Friedman, and E. Kodesh Stress-related genomic responses during the course of heat acclimation and its association with ischemic-reperfusion cross-tolerance J Appl Physiol, October 1, 2004; 97(4): 1496 - 1507. [Abstract] [Full Text] [PDF]

				D. M. Katschinski On Heat and Cells and Proteins Physiology, February 1, 2004; 19(1): 11 - 15. [Abstract] [Full Text] [PDF]

				D. M. Katschinski and S. B. Glueck Hot worms can handle heavy metal. Focus on "HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans" Physiol Genomics, June 24, 2003; 14(1): 1 - 2. [Full Text] [PDF]

				J. Campisi, T. H. Leem, B. N. Greenwood, M. K. Hansen, A. Moraska, K. Higgins, T. P. Smith, and M. Fleshner Habitual physical activity facilitates stress-induced HSP72 induction in brain, peripheral, and immune tissues Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2003; 284(2): R520 - R530. [Abstract] [Full Text] [PDF]

				A. Maloyan and M. Horowitz beta -Adrenergic signaling and thyroid hormones affect HSP72 expression during heat acclimation J Appl Physiol, July 1, 2002; 93(1): 107 - 115. [Abstract] [Full Text] [PDF]

				A. Bouchama and J. P. Knochel Heat Stroke N. Engl. J. Med., June 20, 2002; 346(25): 1978 - 1988. [Full Text] [PDF]

				K. C. Kregel Molecular Biology of Thermoregulation: Invited Review: Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance J Appl Physiol, May 1, 2002; 92(5): 2177 - 2186. [Abstract] [Full Text] [PDF]

				W. J. Becker and J. G. Cannon Influence of barometric pressure on interleukin-1{beta} secretion Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2001; 280(6): R1897 - R1901. [Abstract] [Full Text] [PDF]

				E. Fehrenbach, A. M. Niess, R. Veith, H.-H. Dickhuth, and H. Northoff Changes of HSP72-expression in leukocytes are associated with adaptation to exercise under conditions of high environmental temperature J. Leukoc. Biol., May 1, 2001; 69(5): 747 - 754. [Abstract] [Full Text]

				H. H. Patel, A. Hsu, and G. J. Gross Cardioprotection is strain dependent in rat in response to whole body hyperthermia Am J Physiol Heart Circ Physiol, March 1, 2001; 280(3): H1208 - H1214. [Abstract] [Full Text] [PDF]

				Y. Mizushima, P. Wang, D. Jarrar, W. G. Cioffi, K. I. Bland, and I. H. Chaudry Preinduction of heat shock proteins protects cardiac and hepatic functions following trauma and hemorrhage Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2000; 278(2): R352 - R359. [Abstract] [Full Text] [PDF]