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Vol. 83, Issue 5, 1413-1417, 1997
Pulmonary, Allergy, and Critical Care Division, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131-5271
Moseley, Pope L. Heat shock proteins and
heat adaptation of the whole organism. J. Appl.
Physiol. 83(5): 1413-1417, 1997.
Adaptation to
heat may occur through acclimatization or thermotolerance; however, the
linkage of these phenomena is poorly understood. The importance of heat
shock proteins (HSPs) in thermotolerance and differences in their
accumulation in organisms adapted to the heat suggest a role for HSPs
in acclimatization as well. The role of HSPs in heat adaptation of the
whole organism and the interrelationships among heat adaptation,
endotoxin tolerance, and cytokine resistance through HSPs are reviewed.
acclimatization; thermotolerance
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