| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892
Received 26 March 1996; accepted in final form 6 May 1997.
Ryschon, T. W., Fowler, R. E. Wysong, A.-R. Anthony, and R. S. Balaban. Efficiency of human skeletal muscle in vivo: comparison of isometric, concentric, and eccentric muscle action. J. Appl. Physiol. 83(3): 867-874, 1997.
The purpose of this study was to estimate the efficiency of ATP
utilization for concentric, eccentric, and isometric muscle action in
the human tibialis anterior and extensor digitorum longus in vivo. A
dynamometer was used to quantitate muscle work, or tension, while
simultaneous 31P-nuclear magnetic
resonance data were collected to monitor ATP, phosphocreatine,
inorganic phosphate, and pH. The relative efficiency of the actions was
estimated in two ways: steady-state effects on high-energy
phosphates and a direct comparison of ATP synthesis rates with work. In
the steady state, the cytosolic free energy dropped to the lowest value
with concentric activity, followed by eccentric and isometric action
for comparative muscle tensions. Estimates of ATP synthesis rates
revealed a mechanochemical efficiency [i.e., ATP production
rate/work (both in J/s)] of 15.0 ± 1.3% in concentric and
34.7 ± 6.1% in eccentric activity. The estimated maximum ATP
production rate was highest in concentric action, suggesting an
activation of energy metabolism under these conditions. By using direct
measures of metabolic strain and ATP turnover, these data demonstrate a
decreasing metabolic efficiency in human muscle action from isometric,
to eccentric, to concentric action.
phosphorus 31-nuclear magnetic resonance; tibialis anterior; extensor digitorum longus; phosphocreatine; magnetic resonance imaging; adenosine 5
-triphosphate
This article has been cited by other articles:
|
|
 |
|
  S. J. Choi and J. J. Widrick Combined effects of fatigue and eccentric damage on muscle power J Appl Physiol, October 1, 2009; 107(4): 1156 - 1164. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. G. Larsen, D. M. Callahan, S. A. Foulis, and J. A. Kent-Braun In vivo oxidative capacity varies with muscle and training status in young adults J Appl Physiol, September 1, 2009; 107(3): 873 - 879. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M Roig, K O'Brien, G Kirk, R Murray, P McKinnon, B Shadgan, and W D Reid The effects of eccentric versus concentric resistance training on muscle strength and mass in healthy adults: a systematic review with meta-analysis Br. J. Sports Med., August 1, 2009; 43(8): 556 - 568. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Rolian, D. E. Lieberman, J. Hamill, J. W. Scott, and W. Werbel Walking, running and the evolution of short toes in humans J. Exp. Biol., March 1, 2009; 212(5): 713 - 721. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Sawicki and D. P. Ferris Powered ankle exoskeletons reveal the metabolic cost of plantar flexor mechanical work during walking with longer steps at constant step frequency J. Exp. Biol., January 1, 2009; 212(1): 21 - 31. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Sawicki and D. P. Ferris Mechanics and energetics of incline walking with robotic ankle exoskeletons J. Exp. Biol., January 1, 2009; 212(1): 32 - 41. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. N. Scholz, M. F. Bobbert, A. J. van Soest, J. R. Clark, and J. van Heerden Running biomechanics: shorter heels, better economy J. Exp. Biol., October 15, 2008; 211(20): 3266 - 3271. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Sawicki and D. P. Ferris Mechanics and energetics of level walking with powered ankle exoskeletons J. Exp. Biol., May 1, 2008; 211(9): 1402 - 1413. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Jubrias, N. K. Vollestad, R. K. Gronka, and M. J. Kushmerick Contraction coupling efficiency of human first dorsal interosseous muscle J. Physiol., April 1, 2008; 586(7): 1993 - 2002. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Giannesini, M. Izquierdo, Y. L. Fur, P. J Cozzone, and D. Bendahan In vivo reduction in ATP cost of contraction is not related to fatigue level in stimulated rat gastrocnemius muscle J. Physiol., November 1, 2001; 536(3): 905 - 915. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Wretman, A. Lionikas, U. Widegren, J. Lannergren, H. Westerblad, and J. Henriksson Effects of concentric and eccentric contractions on phosphorylation of MAPKerk1/2 and MAPKp38 in isolated rat skeletal muscle J. Physiol., August 15, 2001; 535(1): 155 - 164. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Combs, A. H. Aletras, and R. S. Balaban Effect of muscle action and metabolic strain on oxidative metabolic responses in human skeletal muscle J Appl Physiol, November 1, 1999; 87(5): 1768 - 1775. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
