| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Laboratories of Health Evaluation and Exercise Physiology, Division of Health Promotion, National Institute of Health and Nutrition, Toyama 1-23-1, Shinjuku-city, Tokyo 162, Japan
Received 16 December 1996; accepted in final form 14 April 1997.
Kawanaka, Kentaro, Izumi Tabata, and Mitsuru
Higuchi. More tetanic contractions are required
for activating glucose transport maximally in trained muscle.
J. Appl. Physiol. 83(2): 429-433, 1997.
Exercise training increases contraction-stimulated maximal
glucose transport and muscle glycogen level in skeletal muscle.
However, there is a possibility that more muscle contractions are
required to maximally activate glucose transport in trained than in
untrained muscle, because increased glycogen level after training may
inhibit glucose transport. Therefore, the purpose of this study was to
investigate the relationship between the increase in glucose transport
and the number of tetanic contractions in trained and untrained muscle.
Male rats swam 2 h/day for 15 days. In untrained epitrochlearis muscle,
resting glycogen was 26.6 µmol glucose/g muscle. Ten, 10-s-long
tetani at a rate of 1 contraction/min decreased glycogen level to 15.4 µmol glucose/g muscle and maximally increased
2-deoxy-D-glucose
(2-DG) transport. Training increased
contraction-stimulated maximal 2-DG transport (+71%;
P < 0.01), GLUT-4 protein content
(+78%; P < 0.01), and resting
glycogen level (to 39.3 µmol glucose/g muscle;
P < 0.01) on the next day after the
training ended, although this training effect might be due, at least in
part, to last bout of exercise. In trained muscle, 20 tetani were
necessary to maximally activate glucose transport. Twenty tetani
decreased muscle glycogen to a lower level than 10 tetani (18.9 vs.
24.0 µmol glucose/g muscle; P < 0.01). Contraction-stimulated 2-DG transport was negatively correlated
with postcontraction muscle glycogen level in trained (r = 
0.60;
P < 0.01) and untrained muscle
(r = 0.57;
P < 0.01).
muscle glycogen; epitrochlearis; 2-deoxy-D-glucose transport
This article has been cited by other articles:
|
|
 |
|
  R. Sancho, J. Kim, and G. D. Cartee Decreased contraction-stimulated glucose transport in isolated epitrochlearis muscles of pregnant rats J Appl Physiol, March 1, 2005; 98(3): 1021 - 1027. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Kim, R. S. Solis, E. B. Arias, and G. D. Cartee Postcontraction insulin sensitivity: relationship with contraction protocol, glycogen concentration, and 5' AMP-activated protein kinase phosphorylation J Appl Physiol, February 1, 2004; 96(2): 575 - 583. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Aslesen, E. M. L. Engebretsen, J. Franch, and J. Jensen Glucose uptake and metabolic stress in rat muscles stimulated electrically with different protocols J Appl Physiol, September 1, 2001; 91(3): 1237 - 1244. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Kristiansen, J. Gade, J. F. P. Wojtaszewski, B. Kiens, and E. A. Richter Glucose uptake is increased in trained vs. untrained muscle during heavy exercise J Appl Physiol, September 1, 2000; 89(3): 1151 - 1158. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kawanaka, I. Tabata, A. Tanaka, and M. Higuchi Effects of high-intensity intermittent swimming on glucose transport in rat epitrochlearis muscle J Appl Physiol, June 1, 1998; 84(6): 1852 - 1857. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. A. Richter, P. Jensen, B. Kiens, and S. Kristiansen Sarcolemmal glucose transport and GLUT-4 translocation during exercise are diminished by endurance training Am J Physiol Endocrinol Metab, January 1, 1998; 274(1): E89 - E95. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
