Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 83: 129-133, 1997;
8750-7587/97 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Horcajada, M.-N.
Right arrow Articles by Barlet, J.-P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Horcajada, M.-N.
Right arrow Articles by Barlet, J.-P.

Journal of Applied Physiology
Vol. 83, No. 1, pp. 129-133, July 1997
METABOLISM

Influence of treadmill running on femoral bone in young orchidectomized rats

M.-N. Horcajada1, V. Coxam1, M.-J. Davicco1, N. Gaumet1, P. Pastoureau2, C. Leterrier3, J. Culioli1, and J.-P. Barlet1

1 Institut National de la Recherche Agronomique Clermont-Theix, F-63122 Ceyrat; 2 Laboratoires Servier, F-92150 Suresnes; and 3 Institut National de la Recherche Agronomique Nouzilly, F-37380 Nouzilly, France

Received 22 July 1996; accepted in final form 11 March 1997.

Horcajada, M.-N., V. Coxam, M.-J. Davicco, N. Gaumet, P. Pastoureau, C. Leterrier, J. Culioli, and J.-P. Barlet. Influence of treadmill running on femoral bone in young orchidectomized rats. J. Appl. Physiol. 83(1): 129-133, 1997.---Forty 6-wk-old male Wistar rats weighing 308 ± 24 g were divided into two groups. On day 0, the 20 animals in one group were surgically castrated and the other group was sham operated. Within each group, 10 rats were selected for treadmill running (60% maximal O2 consumption, 1 h/day, 6 days/wk for 15 wk). The 20 sedentary rats were used as controls. At the time the rats were killed (day 105), running had no significant effect on femoral mechanical properties either in castrated or in sham-operated rats. Femoral bone density was lower in orchidectomized than in sham-operated rats. Nevertheless, it was higher in exercised than in sedentary rats. Femoral Ca content paralleled changes in bone density. Treadmill running had no significant effect on plasma osteocalcin concentration but inhibited the increase in urinary deoxypyridinoline excretion observed in castrated rats. Image analysis (measured at the distal femoral diaphysis) revealed that these effects mainly resulted from decreased trabecular bone resorption in castrated exercised rats.

osteoporosis; exercise; osteocalcin; deoxypyridinoline

0161-7567/97 $5.00 Copyright © 1997 the American Physiological Society




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
J. Wu, X. X. Wang, H. Chiba, M. Higuchi, M. Takasaki, A. Ohta, and Y. Ishimi
Combined intervention of exercise and genistein prevented androgen deficiency-induced bone loss in mice
J Appl Physiol, January 1, 2003; 94(1): 335 - 342.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
T. Notomi, Y. Okazaki, N. Okimoto, Y. Tanaka, T. Nakamura, and M. Suzuki
Effects of tower climbing exercise on bone mass, strength, and turnover in orchidectomized growing rats
J Appl Physiol, September 1, 2002; 93(3): 1152 - 1158.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online