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O2 peak and the
capillary supply to skeletal muscle
Department of Physiology, Graduate Department of Community Health, and Department of Physical Therapy, University of Toronto, Toronto, Ontario, Canada M5S 3J7
Received 23 September 1996; accepted in final form 19 December 1996.
Hepple, R. T., S. L. M. Mackinnon, J. M. Goodman, S. G. Thomas, and M. J. Plyley. Resistance and aerobic training in older
men: effects on
O2 peak and the
capillary supply to skeletal muscle. J. Appl.
Physiol. 82(4): 1305-1310, 1997.
Both aerobic training (AT) and resistance training (RT) may increase aerobic power
(O2 peak) in the
older population; however, the role of changes in the capillary supply
in this response has not been evaluated. Twenty healthy
men (age 65-74 yr) engaged in either 9 wk of lower body RT
followed by 9 wk of AT on a cycle ergometer (RT
AT group) or 18 wk of AT on a cycle ergometer (ATAT group). RT was performed
three times per week and consisted of three sets of four exercises at
6-12 repetitions maximum. AT was performed three
times per week for 30 min at 60-70% heart rate
reserve. O2 peak was increased
after both RT and AT (P < 0.05).
Biopsies (vastus lateralis) revealed that the number of capillaries per fiber perimeter length was increased after both AT and RT
(P < 0.05), paralleling the changes
in O2 peak, whereas
capillary density was increased only after AT
(P < 0.01). These results, and the
finding of a significant correlation between the change in capillary
supply and O2 peak
(r = 0.52), suggest the possibility that similar mechanisms may be involved in the increase of
O2 peak after
high-intensity RT and AT in the older population.
capillaries; aerobic power; aging; oxygen flux
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