Journal of Applied Physiology Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 82: 852-858, 1997;
8750-7587/97 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hakim, T. S.
Right arrow Articles by Camporesi, E. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hakim, T. S.
Right arrow Articles by Camporesi, E. M.

Journal of Applied Physiology
Vol. 82, No. 3, pp. 852-858, March 1997
PULMONARY CIRCULATION AND LUNG FLUID BALANCE

Segmental pulmonary vascular responses to ATP in rat lungs: role of nitric oxide

Tawfic S. Hakim, Lara Ferrario, Jeffrey C. Freedman, Robert E. Carlin, and Enrico M. Camporesi

Departments of Surgery, Anesthesiology, and Physiology, State University of New York Health Science Center, Syracuse, New York, 13210

Received 3 May 1996; accepted in final form 1 November 1996.

Hakim, Tawfic S., Lara Ferrario, Jeffrey C. Freedman, Robert E. Carlin, and Enrico M. Camporesi. Segmental pulmonary vascular responses to ATP in rat lungs: role of nitric oxide. J. Appl. Physiol. 82(3): 852-858, 1997.---ATP exhibits vascular pressor and depressor responses in a dose- and tone-dependent manner. The vascular site of ATP-induced contraction or dilation has not previously been characterized. Using the vascular occlusion technique, we investigated the effects of ATP in isolated rat lungs perfused with autologous blood (hematocrit = 20%) and described its action during resting and elevated tone in terms of changes in resistances of the small and large arteries and veins. During resting tone, ATP (10-5 M)

purines; adenosine 5'-triphosphate; pulmonary vascular resistance; thromboxane; segmental resistance; occlusion; hypoxia; endothelium-derived relaxing factor

0161-7567/97 $5.00 Copyright © 1997 the American Physiological Society




This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
G. G. Konduri, I. Bakhutashvili, R. Frenn, I. Chandrasekhar, E. R. Jacobs, and A. K. Khanna
P2Y purine receptor responses and expression in the pulmonary circulation of juvenile rabbits
Am J Physiol Heart Circ Physiol, July 1, 2004; 287(1): H157 - H164.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
R. S. Sprague, J. J. Olearczyk, D. M. Spence, A. H. Stephenson, R. W. Sprung, and A. J. Lonigro
Extracellular ATP signaling in the rabbit lung: erythrocytes as determinants of vascular resistance
Am J Physiol Heart Circ Physiol, July 11, 2003; 285(2): H693 - H700.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
B. R. Walker, T. C. Resta, and L. D. Nelin
Nitric oxide-dependent pulmonary vasodilation in polycythemic rats
Am J Physiol Heart Circ Physiol, November 1, 2000; 279(5): H2382 - H2389.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
V. Hampl and J. Herget
Role of Nitric Oxide in the Pathogenesis of Chronic Pulmonary Hypertension
Physiol Rev, October 1, 2000; 80(4): 1337 - 1372.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online