| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Department of Health and Kinesiology, 2 Department of Biochemistry/Biophysics, and 3 Health Sciences Center, College of Medicine, Texas A&M University, College Station, Texas 77843; and 4 Health Management Center, Baptist Medical Center, Little Rock, Arkansas 72119
Received 21 March 1996; accepted in final form 6 September 1996.
Crouse, Stephen F., Barbara C. O'Brien, Peter W. Grandjean,
Robert C. Lowe, J. James Rohack, John S. Green, and Homer Tolson. Training intensity, blood lipids, and apolipoproteins in men with
high cholesterol. J. Appl. Physiol.
82(1): 270-277, 1997.
Twenty-six hypercholesterolemic men (mean
cholesterol, 258 mg/dl; age, 47 yr; weight, 81.9 kg) completed 24 wk of
cycle ergometer training (3 days/wk, 350 kcal/session) at either high
(n = 12) or moderate (n = 14) intensity (80 and 50%
maximal O2 uptake, respectively, randomly assigned) to test the influence of training intensity on blood
lipid and apolipoprotein (apo) concentrations. All
physiological, lipid, and apo measurements were completed at 0, 8, 16, and 24 wk. Lipid data were analyzed via two × four
repeated-measures analysis of variance (
= 0.0031). Training
produced a significant decrease in body weight and increase in maximal
O2 uptake. No interactions between
intensity and weeks of training were noted for any lipid or apo
variable, and no between-group differences were significant before or
throughout training. Therefore, intensity did not affect the training
response. Regardless of intensity, apo AI and apo B fell 9 and 13%,
respectively, by week 16 and remained
lower through week 24 (P < 0.0003). Total cholesterol fell
transiently (
5.5%) by week 16 (P < 0.0021) but returned to initial
levels by week 24. Triglyceride,
low-density-lipoprotein cholesterol, and high-density-lipoprotein (HDL)
cholesterol did not change with training. In contrast,
HDL2 cholesterol rose 79% above
initial levels by week 8 and 82%
above initial levels by week 24 (P < 0.0018);
HDL3 cholesterol fell 8 and 13%
over the same training intervals (P < 0.0026). These data show that changes in blood lipid and apo
concentrations that accompany training in hypercholesterolemic men are
not influenced by exercise intensity when caloric expenditure is held
constant.
exercise; hypercholesterolemia; lipoproteins
This article has been cited by other articles:
|
|
 |
|
  G. S. Metsios, A. Stavropoulos-Kalinoglou, J. J. C. S. Veldhuijzen van Zanten, G. J. Treharne, V. F. Panoulas, K. M. J. Douglas, Y. Koutedakis, and G. D. Kitas Rheumatoid arthritis, cardiovascular disease and physical exercise: a systematic review Rheumatology, March 1, 2008; 47(3): 239 - 248. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. K. Pedersen State of the Art Reviews: Health Benefits Related to Exercise in Patients With Chronic Low-Grade Systemic Inflammation American Journal of Lifestyle Medicine, August 1, 2007; 1(4): 289 - 298. [Abstract] [PDF]
|
|
|
|
 |
|
 J. Larry Durstine and G. W. Lyerly No physical activity or exercise is not an option J Appl Physiol, August 1, 2007; 103(2): 417 - 418. [Full Text] [PDF]
|
|
|
|
 |
|
 S. Kodama, S. Tanaka, K. Saito, M. Shu, Y. Sone, F. Onitake, E. Suzuki, H. Shimano, S. Yamamoto, K. Kondo, et al. Effect of Aerobic Exercise Training on Serum Levels of High-Density Lipoprotein Cholesterol: A Meta-analysis Arch Intern Med, May 28, 2007; 167(10): 999 - 1008. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. O'Donovan, A. Owen, S. R. Bird, E. M. Kearney, A. M. Nevill, D. W. Jones, and K. Woolf-May Changes in cardiorespiratory fitness and coronary heart disease risk factors following 24 wk of moderate- or high-intensity exercise of equal energy cost J Appl Physiol, May 1, 2005; 98(5): 1619 - 1625. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. E. Kraus, J. A. Houmard, B. D. Duscha, K. J. Knetzger, M. B. Wharton, J. S. McCartney, C. W. Bales, S. Henes, G. P. Samsa, J. D. Otvos, et al. Effects of the Amount and Intensity of Exercise on Plasma Lipoproteins N. Engl. J. Med., November 7, 2002; 347(19): 1483 - 1492. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. S. Bernstein, M. C. Costanza, R. W. James, M. A. Morris, F. Cambien, S. Raoux, and A. Morabia Physical Activity May Modulate Effects of ApoE Genotype on Lipid Profile Arterioscler. Thromb. Vasc. Biol., January 1, 2002; 22(1): 133 - 140. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. M. Gotto Jr Low High-Density Lipoprotein Cholesterol as a Risk Factor in Coronary Heart Disease : A Working Group Report Circulation, May 1, 2001; 103(17): 2213 - 2218. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
